''Atopobium'' is a genus of
Actinomycetota
The Actinomycetota (or Actinobacteria) are a diverse phylum of Gram-positive bacteria with high GC content. They can be terrestrial or aquatic. They are of great importance to land flora because of their contributions to soil systems. In soil t ...
, in the family
Coriobacteriaceae
The Coriobacteriaceae is a family of Actinomycetota. The family ''Coriobacteriaceae'' has been shown to increase significantly in the ceca of mice in response to stress.
Phylogeny
The currently accepted taxonomy is based on the List of Prokaryo ...
. ''Atopobium'' species are anaerobic, Gram-positive rod-shaped or elliptical bacteria found as single elements or in pairs or short chains.
''
Atopobium vaginae
''Fannyhessea vaginae'' is a species of bacteria in the family ''Atopobiaceae''. It is a facultative anaerobic organism, anaerobic, Gram-positive rod-shaped or elliptical coccobacillus found as single elements or in pairs or short chains. It is ...
'' was discovered in 1999.
This is a facultative anaerobic bacteria, which form small colonies on blood agar at 37 °C is also positive for acid phosphatase. This species has now been reclassified into the genus ''Fannyhessea'' following phylogenetic studies.
Clinical significance
The genus ''Atopobium'' may be associated with
bacterial vaginosis
Bacterial vaginosis (BV) is an infection of the vagina caused by excessive growth of bacteria. Common symptoms include increased vaginal discharge that often smells like fish. The discharge is usually white or gray in color. Burning with urina ...
.
The genus may play a role in the development of
Colorectal cancer
Colorectal cancer (CRC), also known as bowel cancer, colon cancer, or rectal cancer, is the development of cancer from the Colon (anatomy), colon or rectum (parts of the large intestine). Signs and symptoms may include Lower gastrointestinal ...
. While the genus has been reported as overrepresented in feces of patients,
''
A. minutum'' has conversely shown a mild apoptotic effect on cancer cells ''in vitro'' and has been suggested to be comparable to probiotic bacteria in regards to colorectal cancer.
Phylogeny
The currently accepted taxonomy is based on the
List of Prokaryotic names with Standing in Nomenclature
List of Prokaryotic names with Standing in Nomenclature (LPSN) is an online database that maintains information on the naming and taxonomy of prokaryotes, following the taxonomy requirements and rulings of the International Code of Nomenclatu ...
(LPSN)
and
National Center for Biotechnology Information
The National Center for Biotechnology Information (NCBI) is part of the National Library of Medicine (NLM), a branch of the National Institutes of Health (NIH). It is approved and funded by the government of the United States. The NCBI is lo ...
(NCBI).
See also
*
List of bacterial vaginosis microbiota
Bacterial vaginosis is caused by an imbalance of the naturally occurring bacteria in the vagina. The normally predominant species of ''Lactobacilli'' are markedly reduced. This is the list of organisms that are found in the vagina that are asso ...
*
List of bacteria genera
This article lists the genera of the bacteria
Bacteria (; : bacterium) are ubiquitous, mostly free-living organisms often consisting of one Cell (biology), biological cell. They constitute a large domain (biology), domain of Prokaryote, ...
*
List of bacterial orders
This article lists the orders of the Bacteria. The currently accepted taxonomy is based on the List of Prokaryotic names with Standing in Nomenclature (LPSN) and National Center for Biotechnology Information (NCBI)
and the phylogeny is based on 16 ...
References
External links
*https://web.archive.org/web/20070929134318/http://sn2000.taxonomy.nl/Main/Classification/112091.htm
Coriobacteriaceae
Bacteria genera
{{actinobacteria-stub