Arthur C. Cope (June 27, 1909 – June 4, 1966) was an American
organic chemist
Organic chemistry is a subdiscipline within chemistry involving the science, scientific study of the structure, properties, and reactions of organic compounds and organic matter, organic materials, i.e., matter in its various forms that contain ...
and member of the
United States National Academy of Sciences
The National Academy of Sciences (NAS) is a United States nonprofit, non-governmental organization. NAS is part of the National Academies of Sciences, Engineering, and Medicine, along with the National Academy of Engineering (NAE) and the Nati ...
. He is credited with the development of several important chemical reactions which bear his name including the
Cope elimination and the
Cope rearrangement.
Cope was born on June 27, 1909, in
Dunreith, Indiana. He received a bachelor's degree in chemistry from
Butler University
Butler University is a private university in Indianapolis, Indiana, United States. Founded in 1855 and named after founder Ovid Butler, the university has over 60 major academic fields of study within six colleges in the arts, business, communic ...
in
Indianapolis
Indianapolis ( ), colloquially known as Indy, is the List of capitals in the United States, capital and List of municipalities in Indiana, most populous city of the U.S. state of Indiana and the county seat of Marion County, Indiana, Marion ...
in 1929 and a PhD in 1932 from the
University of Wisconsin–Madison
The University of Wisconsin–Madison (University of Wisconsin, Wisconsin, UW, UW–Madison, or simply Madison) is a public land-grant research university in Madison, Wisconsin, United States. It was founded in 1848 when Wisconsin achieved st ...
. His research continued at Harvard University in 1933 as a National Research Council Fellow. In 1934, he joined the faculty of
Bryn Mawr College
Bryn Mawr College ( ; Welsh language, Welsh: ) is a Private college, private Women's colleges in the United States, women's Liberal arts colleges in the United States, liberal arts college in Bryn Mawr, Pennsylvania, United States. Founded as a ...
. There, his research included the first syntheses of a number of
barbiturate
Barbiturates are a class of depressant, depressant drugs that are chemically derived from barbituric acid. They are effective when used medication, medically as anxiolytics, hypnotics, and anticonvulsants, but have physical and psychological a ...
s including
delvinyl sodium. At Bryn Mawr, Cope also developed a reaction involving the thermal rearrangement of an
allyl
In organic chemistry, an allyl group is a substituent with the structural formula . It consists of a methylene bridge () attached to a vinyl group (). The name is derived from the scientific name for garlic, . In 1844, Theodor Wertheim isolated a ...
group which eventually became known as the Cope rearrangement.
In 1941, Cope moved to
Columbia University
Columbia University in the City of New York, commonly referred to as Columbia University, is a Private university, private Ivy League research university in New York City. Established in 1754 as King's College on the grounds of Trinity Churc ...
where he worked on projects associated with the war effort including chemical warfare agents, antimalarial drugs, and treatments for
mustard gas
Mustard gas or sulfur mustard are names commonly used for the organosulfur compound, organosulfur chemical compound bis(2-chloroethyl) sulfide, which has the chemical structure S(CH2CH2Cl)2, as well as other Chemical species, species. In the wi ...
poisoning. In 1945, he moved to the
Massachusetts Institute of Technology
The Massachusetts Institute of Technology (MIT) is a Private university, private research university in Cambridge, Massachusetts, United States. Established in 1861, MIT has played a significant role in the development of many areas of moder ...
to become the head of the Department of Chemistry.
Awards and honors
*1944
American Chemical Society Award in Pure Chemistry
*1945 Elected to the
American Academy of Arts and Sciences
The American Academy of Arts and Sciences (The Academy) is one of the oldest learned societies in the United States. It was founded in 1780 during the American Revolution by John Adams, John Hancock, James Bowdoin, Andrew Oliver, and other ...
*1947 Elected to the
National Academy of Sciences
The National Academy of Sciences (NAS) is a United States nonprofit, NGO, non-governmental organization. NAS is part of the National Academies of Sciences, Engineering, and Medicine, along with the National Academy of Engineering (NAE) and the ...
.
*1961 Elected to the
American Philosophical Society
The American Philosophical Society (APS) is an American scholarly organization and learned society founded in 1743 in Philadelphia that promotes knowledge in the humanities and natural sciences through research, professional meetings, publicat ...
Today, the
Arthur C. Cope Award, in honor of his memory, is given out annually by the
American Chemical Society
The American Chemical Society (ACS) is a scientific society based in the United States that supports scientific inquiry in the field of chemistry. Founded in 1876 at New York University, the ACS currently has more than 155,000 members at all ...
to the most outstanding organic chemist.
References
Literature
*
External links
National Academy of Sciences Biographical Memoir
{{DEFAULTSORT:Cope, Arthur C.
1909 births
1966 deaths
Members of the United States National Academy of Sciences
Columbia University faculty
American organic chemists
20th-century American chemists
Butler University alumni
University of Wisconsin–Madison alumni
Harvard University staff
Bryn Mawr College faculty
Members of the American Philosophical Society