In
enzymology
Enzymes () are proteins that act as biological catalysts by accelerating chemical reactions. The molecules upon which enzymes may act are called substrates, and the enzyme converts the substrates into different molecules known as products. A ...
, an arsenite-transporting ATPase () is an
enzyme
Enzymes () are proteins that act as biological catalysts by accelerating chemical reactions. The molecules upon which enzymes may act are called substrates, and the enzyme converts the substrates into different molecules known as products. A ...
that
catalyzes
Catalysis () is the process of increasing the rate of a chemical reaction by adding a substance known as a catalyst (). Catalysts are not consumed in the reaction and remain unchanged after it. If the reaction is rapid and the catalyst recyc ...
the
chemical reaction
A chemical reaction is a process that leads to the IUPAC nomenclature for organic transformations, chemical transformation of one set of chemical substances to another. Classically, chemical reactions encompass changes that only involve the pos ...
:ATP + H
2O + arsenitein
ADP + phosphate + arseniteout
The 3
substrates of this enzyme are
ATP
ATP may refer to:
Companies and organizations
* Association of Tennis Professionals, men's professional tennis governing body
* American Technical Publishers, employee-owned publishing company
* ', a Danish pension
* Armenia Tree Project, non ...
,
H2O, and
arsenite, whereas its 3
products are
ADP
Adp or ADP may refer to:
Aviation
* Aéroports de Paris, airport authority for the Parisian region in France
* Aeropuertos del Perú, airport operator for airports in northern Peru
* SLAF Anuradhapura, an airport in Sri Lanka
* Ampara Air ...
,
phosphate
In chemistry, a phosphate is an anion, salt, functional group or ester derived from a phosphoric acid. It most commonly means orthophosphate, a derivative of orthophosphoric acid .
The phosphate or orthophosphate ion is derived from phospho ...
, and
arsenite.
This enzyme belongs to the family of
hydrolases, specifically those acting on acid
anhydrides acting on acid anhydrides to catalyse transmembrane movement of substances. The
systematic name of this enzyme class is ATP phosphohydrolase (arsenite-exporting).
Structural studies
As of late 2007, 3
structures have been solved for this class of enzymes, with
PDB accession codes , , and .
See also
*
Arsenite-Antimonite efflux
References
*
*
*
*
EC 3.6.3
Enzymes of known structure
{{3.6-enzyme-stub