Armand Trousseau (14 October 1801 – 23 June 1867) was a French
internist. His contributions to medicine include
Trousseau sign of malignancy,
Trousseau sign of latent tetany
Trousseau sign of latent tetany is a medical sign observed in patients with low calcium. From 1 to 4 percent of normal patients will test positive for Trousseau's sign of latent tetany. This sign may be positive before other manifestations of hypo ...
, Trousseau–Lallemand bodies (an archaic synonym for
Bence Jones protein
Bence Jones protein is a monoclonal globulin protein or immunoglobulin light chain found in the urine, with a molecular weight of 22–24 kDa. Detection of Bence Jones protein may be suggestive of multiple myeloma or Waldenström's macroglobu ...
s). He is sometimes credited with the quip "use new drugs quickly, while they still work", though
Michel-Philippe Bouvart had said the same over 40 years earlier.
[Gaston de Lévis, ''Souvenirs et portraits, 1780-1789'', 1813]
p. 240
/ref>
Biography
A native of Tours
Tours ( , ) is one of the largest cities in the region of Centre-Val de Loire, France. It is the prefecture of the department of Indre-et-Loire. The commune of Tours had 136,463 inhabitants as of 2018 while the population of the whole metr ...
, Indre-et-Loire, Armand Trousseau began his medical studies in his native town as a pupil of Pierre Fidele Bretonneau at the local general hospital. He later continued his studies in Paris, where he received his doctorate in 1825 and became adjunct faculty in 1827. In 1828, the French government assigned him to investigate epidemics ravaging some parts of southern France. After completing his mission the same year, Trousseau travelled to Gibraltar as a member of a commission to investigate yellow fever
Yellow fever is a viral disease of typically short duration. In most cases, symptoms include fever, chills, loss of appetite, nausea, muscle pains – particularly in the back – and headaches. Symptoms typically improve within five days. In ...
. This work, and a monograph on laryngeal phthisis, led to his early recognition in Paris.
In 1830 Trousseau became ''Médecin des hôpitaux'' through concours, and in 1832 received a position in public health with the central bureau while working as a physician in the Hôtel-Dieu under Joseph Claude Anthelme Récamier. In 1837 he received the great prize of the academy. In 1839 he was appointed physician at the Hôpital St. Antoine and eventually became Chair of therapy and pharmacology at the Paris medical faculty. In 1850 he assumed the Chair of clinical medicine and again commenced working in the Hôtel-Dieu. He was also active in politics, particularly after the French Revolution of 1848
The French Revolution of 1848 (french: Révolution française de 1848), also known as the February Revolution (), was a brief period of civil unrest in France, in February 1848, that led to the collapse of the July Monarchy and the foundati ...
, holding several positions including being a member of the legislative body. During his later years Trousseau developed gastric cancer
Stomach cancer, also known as gastric cancer, is a cancer that develops from the lining of the stomach. Most cases of stomach cancers are gastric carcinomas, which can be divided into a number of subtypes, including gastric adenocarcinomas. Ly ...
. Coincidentally, he previously described Trousseau sign of malignancy and developed a similar finding in himself. This cancer limited his activities and eventually proved fatal.
Legacy
Trousseau was instrumental in creating new modes of treatment of croup
Croup, also known as laryngotracheobronchitis, is a type of respiratory infection that is usually caused by a virus. The infection leads to swelling inside the trachea, which interferes with normal breathing and produces the classic symptoms o ...
, emphysema
Emphysema, or pulmonary emphysema, is a lower respiratory tract disease, characterised by air-filled spaces ( pneumatoses) in the lungs, that can vary in size and may be very large. The spaces are caused by the breakdown of the walls of the a ...
, pleurisy
Pleurisy, also known as pleuritis, is inflammation of the membranes that surround the lungs and line the chest cavity ( pleurae). This can result in a sharp chest pain while breathing. Occasionally the pain may be a constant dull ache. Other s ...
, goiter
A goitre, American and British English spelling differences#re er, or goiter, is a swelling in the neck resulting from an enlarged thyroid, thyroid gland. A goitre can be associated with a thyroid that is not functioning properly.
Worldwide, over ...
, and malaria
Malaria is a mosquito-borne infectious disease that affects humans and other animals. Malaria causes symptoms that typically include fever, tiredness, vomiting, and headaches. In severe cases, it can cause jaundice, seizures, coma, or deat ...
. He received the prize of the French Academy of Medicine for his classic essay on laryngology
Laryngology is a branch of medicine that deals with disorders, diseases and injuries of the larynx, colloquially known as the voice box. Laryngologists treat disorders of the larynx, including diseases that affects the voice, swallowing, or upper ...
which originally appeared in 1837. He was the first in France to perform a tracheotomy
Tracheotomy (, ), or tracheostomy, is a surgical airway management procedure which consists of making an incision (cut) on the anterior aspect (front) of the neck and opening a direct airway through an incision in the Vertebrate trachea, trache ...
, and he wrote a monograph on this as well as intubation
Intubation (sometimes entubation) is a medical procedure involving the insertion of a tube into the body. Patients are generally anesthetized beforehand. Examples include tracheal intubation, and the balloon tamponade with a Sengstaken-Blake ...
in 1851. His textbooks on clinical medicine and therapeutics were both extremely popular and translated into English. Trousseau coined the terms aphasia
Aphasia is an inability to comprehend or formulate language because of damage to specific brain regions. The major causes are stroke and head trauma; prevalence is hard to determine but aphasia due to stroke is estimated to be 0.1–0.4% in t ...
and '' forme fruste'' and popularized eponym
An eponym is a person, a place, or a thing after whom or which someone or something is, or is believed to be, named. The adjectives which are derived from the word eponym include ''eponymous'' and ''eponymic''.
Usage of the word
The term ''epon ...
s in disease description such as Addison's disease
Addison's disease, also known as primary adrenal insufficiency, is a rare long-term endocrine disorder characterized by inadequate production of the steroid hormones cortisol and aldosterone by the two outer layers of the cells of the adrena ...
and Hodgkin's lymphoma
Hodgkin lymphoma (HL) is a type of lymphoma, in which cancer originates from a specific type of white blood cell called lymphocytes, where multinucleated Reed–Sternberg cells (RS cells) are present in the patient's lymph nodes. The condition w ...
.
In 1833, Trousseau invented the Trousseau Tracheal Dilator, a blunt-nosed forceps designed to allow easier access to a tracheostomy
Tracheotomy (, ), or tracheostomy, is a surgical airway management procedure which consists of making an incision (cut) on the anterior aspect (front) of the neck and opening a direct airway through an incision in the trachea (windpipe). The re ...
stoma
In botany, a stoma (from Greek ''στόμα'', "mouth", plural "stomata"), also called a stomate (plural "stomates"), is a pore found in the epidermis of leaves, stems, and other organs, that controls the rate of gas exchange. The pore is bo ...
.
Trousseau was considered an outstanding teacher. Numerous students of his achieved fame in their own right, including Puerto Rican pro-independence leader, surgeon and Légion d'honneur
The National Order of the Legion of Honour (french: Ordre national de la Légion d'honneur), formerly the Royal Order of the Legion of Honour ('), is the highest French order of merit, both military and civil. Established in 1802 by Napoleon B ...
laureate, Ramón Emeterio Betances.[Ojeda Reyes, Félix, ''El Desterrado de París'', pp. 20, 29–30] Trousseau’s son Georges Phillipe Trousseau
Georges Phillipe Trousseau (1 May 1833 – 4 May 1894) was a French physician who became the royal doctor of the Kingdom of Hawaii, and engaged in a variety of agricultural ventures.
Biography
Georges Phillipe Trousseau was born in Paris on 1 Ma ...
(1833–1894) became the royal doctor of the Kingdom of Hawaii, and Armand's grandson was the distinguished ophthalmologist
Ophthalmology ( ) is a surgery, surgical subspecialty within medicine that deals with the diagnosis and treatment of eye disorders.
An ophthalmologist is a physician who undergoes subspecialty training in medical and surgical eye care. Followin ...
Armand Henri Trousseau (1856–1910).
References
External links
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{{DEFAULTSORT:Trousseau, Armand
1801 births
1867 deaths
People from Tours, France
19th-century French physicians
Deputies of Eure-et-Loir
Deaths from stomach cancer
Burials at Père Lachaise Cemetery