Aquamid is a non-absorbable soft volume filler for aesthetic and reconstructive purposes. Aquamid is the trade name for a specific formulation of 97.5% water for injection and 2.5% cross-linked

polyacrylamide Polyacrylamide (abbreviated as PAM or pAAM) is a polymer with the formula (-CH2CHCONH2-). It has a linear-chain structure. PAM is highly water-absorbent, forming a soft gel when hydrated. In 2008, an estimated 750,000,000 kg were produced, ...

. It is injected

subcutaneously The subcutaneous tissue (), also called the hypodermis, hypoderm (), subcutis, or superficial fascia, is the lowermost layer of the integumentary system in vertebrates. The types of cells found in the layer are fibroblasts, adipose cells, and m ...

to correct

wrinkle A wrinkle, also known as a rhytid, is a fold, ridge or crease in an otherwise smooth surface, such as on skin or fabric. Skin wrinkles typically appear as a result of ageing processes such as glycation, habitual sleeping positions, loss of b ...

s and folds or to add volume. Common aesthetic indications are nasolabial folds,

lip augmentation Lip augmentation is a cosmetic procedure that modifies the shape of the lips using fillers, such as collagen or implants. The procedure may be performed to increase lip size, correct asymmetry, create protrusion, or adjust the ratio of the top a ...

, cheek contouring, nose enhancement. Aquamid is also used to correct signs of facial lipoatrophy or fat wasting in HIV+ patients. Aquamid has been evaluated in several

clinical trial Clinical trials are prospective biomedical or behavioral research studies on human subject research, human participants designed to answer specific questions about biomedical or behavioral interventions, including new treatments (such as novel v ...

s involving more than 5,000 patients including a comparative trial in the United States. Data from this trial has been used to support a PMA application to the

FDA The United States Food and Drug Administration (FDA or US FDA) is a federal agency of the Department of Health and Human Services. The FDA is responsible for protecting and promoting public health through the control and supervision of food ...

. Aquamid is not yet approved for sale in the United States. Aquamid is developed, produced and commercialized by Contura International.Contura International, It was approved in Europe in 2001 for facial augmentation and minor body contouring and is available in several countries in Europe, Asia, the Middle East and Latin America.

References

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External links

Aquamid Website
Plastic surgery filler Acrylate polymers Polyelectrolytes Gels