Antoine Bernard-Jean Marfan (; June 23, 1858 – February 11, 1942) was a French

paediatrician Pediatrics (American English) also spelled paediatrics (British English), is the branch of medicine that involves the medical care of infants, children, adolescents, and young adults. In the United Kingdom, pediatrics covers many of their yout ...

. He was born in

Castelnaudary Castelnaudary (; ) is a commune in the Aude department in the Occitanie region of southern France. It is located in the former province of the Lauragais and famous for cassoulet of which it claims to be the world capital, and of which it ...

(département

Aude Aude ( ; ) is a Departments of France, department in Southern France, located in the Occitania (administrative region), Occitanie Regions of France, region and named after the river Aude (river), Aude. The departmental council also calls it " ...

Languedoc-Roussillon Languedoc-Roussillon (; ; ) is a former regions of France, administrative region of France. On 1 January 2016, it joined with the region of Midi-Pyrénées to become Occitania (administrative region), Occitania. It comprised five departments o ...

) to Antoine Prosper Marfan and Adélaïde Thuries. He began his medical studies in

Toulouse Toulouse (, ; ; ) is a city in southern France, the Prefectures in France, prefecture of the Haute-Garonne department and of the Occitania (administrative region), Occitania region. The city is on the banks of the Garonne, River Garonne, from ...

, where he stayed for two years before moving to

Paris Paris () is the Capital city, capital and List of communes in France with over 20,000 inhabitants, largest city of France. With an estimated population of 2,048,472 residents in January 2025 in an area of more than , Paris is the List of ci ...

. He graduated in 1886, his education having been interrupted by a period of military service. In 1903 he became a professor of infantile hygiene in the

paediatric Pediatrics (American English) also spelled paediatrics (British English), is the branch of medicine Medicine is the science and Praxis (process), practice of caring for patients, managing the Medical diagnosis, diagnosis, prognosis, Prev ...

clinic of the

University of Paris The University of Paris (), known Metonymy, metonymically as the Sorbonne (), was the leading university in Paris, France, from 1150 to 1970, except for 1793–1806 during the French Revolution. Emerging around 1150 as a corporation associated wit ...

. During the same year, he became a member of the

Académie de Médecine An academy (Attic Greek: Ἀκαδήμεια; Koine Greek Ἀκαδημία) is an institution of tertiary education. The name traces back to Plato's school of philosophy, founded approximately 386 BC at Akademia, a sanctuary of Athena, the go ...

. In 1896, Marfan described a

hereditary disorder A genetic disorder is a health problem caused by one or more abnormalities in the genome. It can be caused by a mutation in a single gene (monogenic) or multiple genes (polygenic) or by a chromosome abnormality. Although polygenic disorders are ...

connective tissue Connective tissue is one of the four primary types of animal tissue, a group of cells that are similar in structure, along with epithelial tissue, muscle tissue, and nervous tissue. It develops mostly from the mesenchyme, derived from the mesod ...

that was to become known as

Marfan syndrome Marfan syndrome (MFS) is a multi-systemic genetic disorder that affects the connective tissue. Those with the condition tend to be tall and thin, with dolichostenomelia, long arms, legs, Arachnodactyly, fingers, and toes. They also typically ha ...

, the term first being used by Henricus Jacobus Marie Weve (1888–1962) of

Utrecht Utrecht ( ; ; ) is the List of cities in the Netherlands by province, fourth-largest city of the Netherlands, as well as the capital and the most populous city of the Provinces of the Netherlands, province of Utrecht (province), Utrecht. The ...

in 1931. Today, it is thought that Marfan's patient (a five-year-old girl named Gabrielle) was affected by a condition known as congenital contractural arachnodactyly, and not Marfan's syndrome.Antoine Marfan - biography
@

Who Named It ''Whonamedit?'' is an online English-language dictionary of medical eponyms and the people associated with their identification. Though it is a dictionary, many eponyms and persons are presented in extensive articles with comprehensive bibliograp ...

Further

eponym An eponym is a noun after which or for which someone or something is, or is believed to be, named. Adjectives derived from the word ''eponym'' include ''eponymous'' and ''eponymic''. Eponyms are commonly used for time periods, places, innovati ...

ous medical conditions named after Antoine Marfan include: *

Dennie–Marfan syndrome Dennie–Marfan syndrome is a syndrome in which there is association of spastic paraplegia of the lower limbs and mental retardation in children with congenital syphilis. Both sexes are affected, and the onset of the disease can be acute or insidio ...

* Marfan's hypermobility syndrome * Marfan's law * Marfan's sign * Marfan's symptom * Marfan–Madelung syndrome Marfan also had interests in the paediatric aspects of

tuberculosis Tuberculosis (TB), also known colloquially as the "white death", or historically as consumption, is a contagious disease usually caused by ''Mycobacterium tuberculosis'' (MTB) bacteria. Tuberculosis generally affects the lungs, but it can al ...

nutrition Nutrition is the biochemistry, biochemical and physiology, physiological process by which an organism uses food and water to support its life. The intake of these substances provides organisms with nutrients (divided into Macronutrient, macro- ...

and

diphtheria Diphtheria is an infection caused by the bacteria, bacterium ''Corynebacterium diphtheriae''. Most infections are asymptomatic or have a mild Course (medicine), clinical course, but in some outbreaks, the mortality rate approaches 10%. Signs a ...

. With Jacques-Joseph Grancher (1843–1907) and Jules Comby (1853–1947), he was co-author of ''Traité des maladies de l’enfance''. From 1913 to 1922, he was publisher of the journal ''Le Nourrisson''.

References

External links

Antoine Marfan
@

1858 births 1942 deaths People from Castelnaudary 19th-century French physicians 20th-century French physicians French pediatricians {{France-med-bio-stub