HOME

TheInfoList



OR:

The Anti-apoptotic Ras signaling cascade is an intracellular
signal transduction Signal transduction is the process by which a chemical or physical signal is transmitted through a cell as a series of molecular events, most commonly protein phosphorylation catalyzed by protein kinases, which ultimately results in a cellular ...
cascade that involves the Ras protein and inhibits apoptosis. It is the target of the cancer drug gefitinib. It may refer to the PI3K/ AKT pathway. It may refer to the
MAPK/ERK pathway The MAPK/ERK pathway (also known as the Ras-Raf-MEK-ERK pathway) is a chain of proteins in the cell that communicates a signal from a receptor on the surface of the cell to the DNA in the nucleus of the cell. The signal starts when a signalin ...
which involves ras and can affect apoptosis.http://www.aacrmeetingabstracts.org/cgi/content/abstract/2005/1/972-b "Pathways potentiated by oncogenic Ras to modulate apoptosis induced by anticancer agent FR901228 " 2005 The anti-apoptotic STAT pathway does not involve Ras.


See also

* Ras subfamily


References


External links



Diagram of ras onwards. Signal transduction Cell cycle Apoptosis {{cell-cycle-stub