Annette Catherine Dolphin (born 1951) is a

Professor Professor (commonly abbreviated as Prof.) is an academic rank at universities and other post-secondary education and research institutions in most countries. Literally, ''professor'' derives from Latin as a "person who professes". Professor ...

of Pharmacology in the Department of

Neuroscience Neuroscience is the science, scientific study of the nervous system (the brain, spinal cord, and peripheral nervous system), its functions and disorders. It is a Multidisciplinary approach, multidisciplinary science that combines physiology, an ...

Physiology Physiology (; ) is the scientific study of functions and mechanisms in a living system. As a sub-discipline of biology, physiology focuses on how organisms, organ systems, individual organs, cells, and biomolecules carry out the chemic ...

and

Pharmacology Pharmacology is a branch of medicine, biology and pharmaceutical sciences concerned with drug or medication action, where a drug may be defined as any artificial, natural, or endogenous (from within the body) molecule which exerts a biochemi ...

University College London , mottoeng = Let all come who by merit deserve the most reward , established = , type = Public research university , endowment = £143 million (2020) , budget = � ...

(UCL).

Education

Dolphin was educated at the

University of Oxford The University of Oxford is a collegiate research university in Oxford, England. There is evidence of teaching as early as 1096, making it the oldest university in the English-speaking world and the world's second-oldest university in contin ...

where she was awarded a Bachelor of Arts degree in

Biochemistry Biochemistry or biological chemistry is the study of chemical processes within and relating to living organisms. A sub-discipline of both chemistry and biology, biochemistry may be divided into three fields: structural biology, enzymology ...

in 1973, and the

Institute of Psychiatry The Institute of Psychiatry, Psychology and Neuroscience (IoPPN) is a research institution dedicated to discovering what causes mental illness and diseases of the brain. In addition, its aim is to help identify new treatments for them and ways ...

at King's College London where she was awarded a PhD in 1977 for research on noradrenaline receptors.

Career and research

Dolphin is a leader in the field of neuronal

voltage-gated calcium channels Voltage-gated calcium channels (VGCCs), also known as voltage-dependent calcium channels (VDCCs), are a group of voltage-gated ion channels found in the membrane of excitable cells (''e.g.'', muscle, glial cells, neurons, etc.) with a permeabil ...

. She is distinguished for her work on the regulation of calcium channel trafficking and function, and the modulation of that function by activation of

G-protein coupled receptors G protein-coupled receptors (GPCRs), also known as seven-(pass)-transmembrane domain receptors, 7TM receptors, heptahelical receptors, serpentine receptors, and G protein-linked receptors (GPLR), form a large group of evolutionarily-related p ...

. Her work on the control of calcium channel trafficking by auxiliary calcium channel subunits has been particularly influential. She has elucidated the topology and processing of this family of proteins. Before working at UCL, Dolphin held appointments at the

Collège de France The Collège de France (), formerly known as the ''Collège Royal'' or as the ''Collège impérial'' founded in 1530 by François I, is a higher education and research establishment ('' grand établissement'') in France. It is located in Paris ...

Yale University Yale University is a Private university, private research university in New Haven, Connecticut. Established in 1701 as the Collegiate School, it is the List of Colonial Colleges, third-oldest institution of higher education in the United Sta ...

, the

National Institute for Medical Research The National Institute for Medical Research (commonly abbreviated to NIMR), was a medical research institute based in Mill Hill, on the outskirts of north London, England. It was funded by the Medical Research Council (MRC); In 2016, the NIMR ...

St George's, University of London St George's, University of London (legally St George's Hospital Medical School, informally St George's or SGUL), is a University located in Tooting in South London and is a constituent college of the University of London. St George's has its o ...

and the

Royal Free Hospital The Royal Free Hospital (also known simply as the Royal Free) is a major teaching hospital in the Hampstead area of the London Borough of Camden. The hospital is part of the Royal Free London NHS Foundation Trust, which also runs services at B ...

Awards and honours

Dolphin has received a number awards for her research, including the British Pharmacological Society (BPS)

Sandoz Novartis AG is a Swiss-American multinational pharmaceutical corporation based in Basel, Switzerland and Cambridge, Massachusetts, United States (global research).name="novartis.com">https://www.novartis.com/research-development/research-loc ...

Prize and the

Pfizer Pfizer Inc. ( ) is an American multinational pharmaceutical and biotechnology corporation headquartered on 42nd Street in Manhattan, New York City. The company was established in 1849 in New York by two German entrepreneurs, Charles Pfize ...

Prize in Biology. She has also been awarded prize lectures such as the G. L. Brown Prize Lecture of

The Physiological Society The Physiological Society, founded in 1876, is a learned society for physiologists in the United Kingdom. History The Physiological Society was founded in 1876 as a dining society "for mutual benefit and protection" by a group of 19 physiologist ...

, the

Julius Axelrod Julius Axelrod (May 30, 1912 – December 29, 2004) was an American biochemist. He won a share of the Nobel Prize in Physiology or Medicine in 1970 along with Bernard Katz and Ulf von Euler. The Nobel Committee honored him for his work on the r ...

Distinguished Lecture in Neuroscience of the

University of Toronto The University of Toronto (UToronto or U of T) is a public research university in Toronto, Ontario, Canada, located on the grounds that surround Queen's Park. It was founded by royal charter in 1827 as King's College, the first institu ...

, the BPS Gary Price Memorial Lecture and, most recently, the

Mary Pickford Gladys Marie Smith (April 8, 1892 – May 29, 1979), known professionally as Mary Pickford, was a Canadian-American stage and screen actress and producer with a career that spanned five decades. A pioneer in the US film industry, she co-founde ...

Lecture of the

University of Edinburgh The University of Edinburgh ( sco, University o Edinburgh, gd, Oilthigh Dhùn Èideann; abbreviated as ''Edin.'' in post-nominals) is a public research university based in Edinburgh, Scotland. Granted a royal charter by King James VI in 15 ...

and the Physiological Society Annual Review Prize Lecture in 2015. One or more of the preceding sentences incorporates text from the royalsociety.org website where: She was elected a

Fellow of the Academy of Medical Sciences Fellowship of the Academy of Medical Sciences (FMedSci) is an award for medical scientists who are judged by the UK Academy of Medical Sciences The Academy of Medical Sciences is an organisation established in the UK in 1998. It is one of ...

(FMedSci) in 1999 and a Fellow of the Royal Society (FRS) in 2015.

References

{{DEFAULTSORT:Dolphin, Annette Living people Fellows of the Royal Society Fellows of the Academy of Medical Sciences (United Kingdom) Academics of University College London Alumni of King's College London British pharmacologists British women scientists Female Fellows of the Royal Society Alumni of the University of Oxford 1951 births