The angle of His, also known as the esophagogastric angle, is the acute angle created between the cardia at the entrance to the

stomach The stomach is a muscular, hollow organ in the upper gastrointestinal tract of Human, humans and many other animals, including several invertebrates. The Ancient Greek name for the stomach is ''gaster'' which is used as ''gastric'' in medical t ...

, and the

esophagus The esophagus (American English), oesophagus (British English), or œsophagus (Œ, archaic spelling) (American and British English spelling differences#ae and oe, see spelling difference) all ; : ((o)e)(œ)sophagi or ((o)e)(œ)sophaguses), c ...

. It helps to prevent reflux of stomach acid into the esophagus. It is commonly undeveloped in

infant In common terminology, a baby is the very young offspring of adult human beings, while infant (from the Latin word ''infans'', meaning 'baby' or 'child') is a formal or specialised synonym. The terms may also be used to refer to juveniles of ...

s, making acid reflux fairly common in adults.

Structure

The angle of His is the

acute angle In Euclidean geometry, an angle can refer to a number of concepts relating to the intersection of two straight lines at a point. Formally, an angle is a figure lying in a plane formed by two rays, called the '' sides'' of the angle, sharing ...

between the

and the

. It is created by the collar sling fibres and the circular muscles around this gastroesophageal junction.

Variation

The angle of His is normally undeveloped in infants, with the esophagus making a vertical junction with the stomach. As a result, reflux of stomach contents is common.

Function

The angle of His forms an anatomical

sphincter A sphincter is a circular muscle that normally maintains constriction of a natural body passage or orifice and relaxes as required by normal physiological functioning. Sphincters are found in many animals. There are over 60 types in the human bo ...

. This prevents the reflux of

stomach acid Gastric acid or stomach acid is the acidic component – hydrochloric acid – of gastric juice, produced by parietal cells in the gastric glands of the stomach lining. In humans, the pH is between one and three, much lower than most other an ...

digestive enzymes Digestive enzymes take part in the chemical process of digestion, which follows the mechanical process of digestion. Food consists of macromolecules of proteins, carbohydrates, and fats that need to be broken down chemically by digestive enzymes ...

, and duodenal

bile Bile (from Latin ''bilis''), also known as gall, is a yellow-green/misty green fluid produced by the liver of most vertebrates that aids the digestion of lipids in the small intestine. In humans, bile is primarily composed of water, is pro ...

from entering the esophagus. This is important in preventing

gastroesophageal reflux disease Gastroesophageal reflux disease (GERD) or gastro-oesophageal reflux disease (GORD) is a chronic upper gastrointestinal disease in which stomach content persistently and regularly flows up into the esophagus, resulting in symptoms and/or ...

and

inflammation Inflammation (from ) is part of the biological response of body tissues to harmful stimuli, such as pathogens, damaged cells, or irritants. The five cardinal signs are heat, pain, redness, swelling, and loss of function (Latin ''calor'', '' ...

of the esophagus.Hiatal Hernia
eMedicine Retrieved 30 January 2010

History

The angle of His is also known as the esophagogastric angle.

References

Digestive system {{Digestive tract