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Angelo Celli (25 March 1857 – 2 November 1914) was an Italian
physician A physician, medical practitioner (British English), medical doctor, or simply doctor is a health professional who practices medicine, which is concerned with promoting, maintaining or restoring health through the Medical education, study, Med ...
, hygienist, parasitologist and
philanthropist Philanthropy is a form of altruism that consists of "private initiatives for the public good, focusing on quality of life". Philanthropy contrasts with business initiatives, which are private initiatives for private good, focusing on material ...
known for his pioneering work on the malarial parasite and control of
malaria Malaria is a Mosquito-borne disease, mosquito-borne infectious disease that affects vertebrates and ''Anopheles'' mosquitoes. Human malaria causes Signs and symptoms, symptoms that typically include fever, Fatigue (medical), fatigue, vomitin ...
. He was Professor of Hygiene at the
University of Palermo The University of Palermo () is a public university, public research university in Palermo, Italy. It was founded in 1806, and is currently organized in 12 Faculties. History The University of Palermo was officially founded in 1806, although it ...
, and then at the
Sapienza University of Rome The Sapienza University of Rome (), formally the Università degli Studi di Roma "La Sapienza", abbreviated simply as Sapienza ('Wisdom'), is a Public university, public research university located in Rome, Italy. It was founded in 1303 and is ...
. He founded the
Pasteur Institute The Pasteur Institute (, ) is a French non-profit private foundation dedicated to the study of biology, micro-organisms, diseases, and vaccines. It is named after Louis Pasteur, who invented pasteurization and vaccines for anthrax and rabies. Th ...
of Italy. With his wife Anna Fraentzel he established a number of medical schools in the Roman Campagna and dispensaries in Rome. He and Ettore Marchiafava correctly described the protozoan parasite that caused malaria and gave it the scientific name ''
Plasmodium ''Plasmodium'' is a genus of unicellular eukaryotes that are obligate parasites of vertebrates and insects. The life cycles of ''Plasmodium'' species involve development in a Hematophagy, blood-feeding insect host (biology), host which then inj ...
'' in 1885. Understanding the nature of malaria, he was among the first scientists to advocate and work for eradication of insects to prevent
infectious diseases infection is the invasion of tissues by pathogens, their multiplication, and the reaction of host tissues to the infectious agent and the toxins they produce. An infectious disease, also known as a transmissible disease or communicable dise ...
. He was elected to the
Senate of the Kingdom of Italy The Senate of the Kingdom of Italy () was the upper house of the bicameral parliament of the Kingdom of Italy, officially created on 4 March 1848, acting as an evolution of the original Subalpine Senate. It was replaced on 1 January 1948 by the ...
in 1892.


Biography

Angelo Celli graduated in medicine in 1878 at the
Sapienza University of Rome The Sapienza University of Rome (), formally the Università degli Studi di Roma "La Sapienza", abbreviated simply as Sapienza ('Wisdom'), is a Public university, public research university located in Rome, Italy. It was founded in 1303 and is ...
. He joined the pathology department as assistant to Tommasi-Crudeli. In 1886, he was appointed Professor of Hygiene at the University of Palermo. He founded the Pasteur Institute at Palermo in 1887. He returned to the University of Rome in 1888 where he worked to his last day. Celli married a German nurse Anna Fraentzel (born 1878), who was known for her voluntary health service during the
First World War World War I or the First World War (28 July 1914 – 11 November 1918), also known as the Great War, was a World war, global conflict between two coalitions: the Allies of World War I, Allies (or Entente) and the Central Powers. Fighting to ...
. They met in
Hamburg Hamburg (, ; ), officially the Free and Hanseatic City of Hamburg,. is the List of cities in Germany by population, second-largest city in Germany after Berlin and List of cities in the European Union by population within city limits, 7th-lar ...
where Celli was on a professional visit. They got married in 1899 and worked together in Rome. Celli died in 1914, and his wife in 1958. They are both interred in the cemetery of Frascati.


Achievements

In 1880 with Ettore Marchiafava Celli studied a new
protozoa Protozoa (: protozoan or protozoon; alternative plural: protozoans) are a polyphyletic group of single-celled eukaryotes, either free-living or parasitic, that feed on organic matter such as other microorganisms or organic debris. Historically ...
n discovered by Alphonse Laveran in the blood of malarial patients. Subsequently, it was shown to be the causative agent of malaria. He studied the biology and pathogenesis of the malarial plasmodium for years after this, working with Ettore Marchiafava, Amico Bignami,
Giovanni Battista Grassi Giovanni Battista Grassi (27 March 1854 – 4 May 1925) was an Italian people, Italian physician and zoologist, best known for his pioneering works on parasitology, especially on malariology. He was Professor of Comparative Zoology at the Unive ...
and Giuseppe Bastianelli. They were the first to use proper staining (with
methylene blue Methylthioninium chloride, commonly called methylene blue, is a salt used as a dye and as a medication. As a medication, it is mainly used to treat methemoglobinemia. It has previously been used for treating cyanide poisoning and urinary trac ...
) to identify malarial parasites as distinct blue-coloured particles in blood cells. They showed that the parasites lived inside the blood cell, and that they divide by simple splitting ( fission). They were the first to recognize several of the stages of development of the malarial parasite in human blood. They called the new microorganism ''
Plasmodium ''Plasmodium'' is a genus of unicellular eukaryotes that are obligate parasites of vertebrates and insects. The life cycles of ''Plasmodium'' species involve development in a Hematophagy, blood-feeding insect host (biology), host which then inj ...
'' in 1885. Their works helped to differentiate different types of malaria as a result of infection with different species of ''Plasmodium''. Angelo Celli is famous in Rome (a
marble sculpture Marble has been the preferred material for stone monumental sculpture since ancient times, with several advantages over its more common geological "parent" limestone, in particular the ability to absorb light a small distance into the surface b ...
of him is in the "Biblioteca dell'Istituto d'Igiene “G. Santarelli” in the Città Universitaria near
Pincio The Pincian Hill ( ; ) is a hill in the northeast quadrant of the historical centre of Rome. The hill lies to the north of the Quirinal, overlooking the Campus Martius. It was outside the original boundaries of the ancient city of Rome, and wa ...
) for his achievements as a hygienist, sociologist, and parliamentary deputy. After the formation of the Chinino di stato (a state organisation controlling prices of drugs, preventing sales of illegal or counterfeit drugs, and prosecuting speculators), he ensured that it applied to malaria medicines. The drugs were soon supplied free to the poor. At the time the
Pontine Marshes 250px, Lake Fogliano, a coastal lagoon in the Pontine Plain The Pontine Marshes ( , ; , formerly also ; [] by Titus Livius, [] and [] by Pliny the Elder''Natural History'' 3.59.) is an approximately quadrangular area of former marshland ...
, the wetlands in Tuscany for instance Maremma and
Basilicata Basilicata (, ; ), also known by its ancient name Lucania (, , ), is an administrative region in Southern Italy, bordering on Campania to the west, Apulia to the north and east, and Calabria to the south. It has two coastlines: a 30-kilometr ...
were malarial areas. Francisco Saverio Nitti asserted that Atella, as an example, remained deserted until the adoption of the laws passed by the Chinino di Stato. Since the populations were illiterate and had a
fatalistic Fatalism is a belief and philosophical doctrine which considers the entire universe as a deterministic system and stresses the subjugation of all events, actions, and behaviors to fate or destiny, which is commonly associated with the cons ...
attitude to malaria, he organized “Le Scuole per i Contadini dell'Agro Romano e le Paludi Pontine,” in English, "Schools for the Peasants of Agro Romano (vast areas of land around Rome)and Paludi Pontine (Pontine Marshes)" to educate and inform them. This scheme was subsequently adopted by Argentina and Greece. Celli's scientific and social achievements led to his receiving the Laurea Honoris Causa from the
University of Athens The National and Kapodistrian University of Athens (NKUA; , ''Ethnikó kai Kapodistriakó Panepistímio Athinón''), usually referred to simply as the University of Athens (UoA), is a public university in Athens, Greece, with various campuses alo ...
and the Royal Society for the Promotion of Health in London. He was awarded the Mary Kingsley medal by the Liverpool School of Tropical Medicine. Although the Celli archives are preserved at the Faculty of experimental medicine and pathology of the Sapienza University of Rome, some letters and documents attesting Celli's constant engagement in favour of public healthcare and his passion as scholar and teacher of hygiene are kept in the library of the
Museo Galileo Museo Galileo (formerly ''Istituto e Museo di Storia della Scienza''; Institute and Museum of the History of Science) is located in Florence, Italy, in Piazza dei Giudici, along the River Arno and close to the Uffizi Gallery. The museum, dedicat ...
in
Florence Florence ( ; ) is the capital city of the Italy, Italian region of Tuscany. It is also the most populated city in Tuscany, with 362,353 inhabitants, and 989,460 in Metropolitan City of Florence, its metropolitan province as of 2025. Florence ...
.


Works

*''Le nostre sostanze alimentari considerate come terreno di coltura di germi patogeni'', Roma, 1888 *''Il primo anno di vita della stazione antirabbica di Palermo'', Roma, 1888 *'' Our food substances considered as a breeding ground for germs,'' Rome, 1888 *'' The first year of the life of the station rabies'' Palermo, Rome, 1888 *''La malaria dei bovini nella campagna romana'', Roma, 1897 nglish version: '' The malaria of cattle in the Roman countryside,'' Rome, 1897*''Stato palustre ed anofelico (paludismo) senza malaria'', Roma, 1902 *''L' opera del medico nella lotta contro la malaria'', Napoli, 1904 *''La malaria nella storia medievale di Roma'', Roma, 1923 nglish version: ''The history of malaria on the Roman Campagna from ancient times''. London, John Bale, Sons Danielsson (1933)


References


Additional sources

*Conci, C. (1975). Repertorio delle biografie e bibliografie degli scrittori e cultori italiani di entomologia. ''Mem. Soc. Ent. Ital.'' 48 1969(4) 817-1069. *Conci, C. & Poggi, R. (1996). Iconography of Italian Entomologists, with essential biographical data. ''Mem. Soc. Ent. Ital''. 75 159-382. *Howard, L. O. (1915). elli, A.''Pop. Sci. Monthly'' 87 72, Portrait. *Howard, L. O. (1930). ''History of applied Entomology (Somewhat Anecdotal)''.Smiths. Miscell. Coll. 84 X+1-564.


External links


Portrait
{{DEFAULTSORT:Celli, Angelo Italian zoologists Italian entomologists 1857 births 1914 deaths Italian pathologists Malariologists Sapienza University of Rome alumni Academic staff of the Sapienza University of Rome Academic staff of the University of Palermo Italian tropical physicians