Amur virus (AMRV) is a
zoonotic
A zoonosis (; plural zoonoses) or zoonotic disease is an infectious disease of humans caused by a pathogen (an infectious agent, such as a virus, bacterium, parasite, fungi, or prion) that can jump from a non-human vertebrate to a human. When h ...
negative-sense single-stranded RNA virus. It may be a member of the genus ''
Orthohantavirus'', but it has not be definitively classified as a
species
A species () is often defined as the largest group of organisms in which any two individuals of the appropriate sexes or mating types can produce fertile offspring, typically by sexual reproduction. It is the basic unit of Taxonomy (biology), ...
and may only be a
strain.
It has been identified as a causative agent of
hemorrhagic fever with renal syndrome
Hantavirus hemorrhagic fever with renal syndrome (HFRS) is a hemorrhagic fever caused by hantaviruses. Symptoms usually occur 12–16 days after exposure to the virus and come in five distinct phases: febrile, hypotensive, low urine production (ol ...
.
Genome
The complete genome sequence Amur virus has been isolated from a sample obtained from ''
Apodemus peninsulae'' in Northeastern China.
AMRV strains from China and Far East and
Soochong virus (SOOV) (especially SOO-1/2 strains from Northeastern Korea) were found to share high identities of nucleotide sequences and were
monophyletic
In biological cladistics for the classification of organisms, monophyly is the condition of a taxonomic grouping being a clade – that is, a grouping of organisms which meets these criteria:
# the grouping contains its own most recent co ...
distinct from ''
Apodemus agrarius''
HTNV. Two genetic sublineages of SOOV exist, but findings suggest that AMRV and SOOV are different strains of the same hantavirus.
Reservoir
The virus is reported to be carried by
Korean field mice (''Apodemus peninsulae'') in the Far East of Russia, China, and Korea.
See also
*
Hantaviruses
''Orthohantavirus'' is a genus of viruses that includes all hantaviruses (family ''Hantaviridae'') that cause disease in humans. Orthohantaviruses, hereafter referred to as hantaviruses, are naturally found primarily in rodents. In general, each ...
*
Viral hemorrhagic fever
Viral hemorrhagic fevers (VHFs) are a diverse group of diseases. "Viral" means a health problem caused by infection from a virus, " hemorrhagic" means to bleed, and "fever" means an unusually high body temperature. Bleeding and fever are comm ...
*
Pulmonary-renal syndrome
*
RNA virus
An RNA virus is a virus characterized by a ribonucleic acid (RNA) based genome. The genome can be single-stranded RNA (ssRNA) or double-stranded (Double-stranded RNA, dsRNA). Notable human diseases caused by RNA viruses include influenza, SARS, ...
*
Murinae
The Old World rats and mice, part of the subfamily Murinae in the family Muridae, comprise at least 519 species. Members of this subfamily are called murines. In terms of species richness, this subfamily is larger than all mammal families excep ...
References
External links
IUCN*
*
{{Taxonbar, from=Q16242878
Viral diseases
Hantaviridae
Hemorrhagic fevers
Rodent-carried diseases
Old World rats and mice