Amit Nilkanth Patel MD, BS, MS is an
Indian-American
Indian Americans or Indo-Americans are citizens of the United States with ancestry from India. The United States Census Bureau uses the term Asian Indian to avoid confusion with Native Americans, who have also historically been referred to ...
cardiac surgeon and was director of clinical regenerative medicine and tissue engineering at the
University of Utah
The University of Utah (U of U, UofU, or simply The U) is a public research university in Salt Lake City, Utah. It is the flagship institution of the Utah System of Higher Education. The university was established in 1850 as the University of De ...
in
Salt Lake City
Salt Lake City (often shortened to Salt Lake and abbreviated as SLC) is the Capital (political), capital and List of cities and towns in Utah, most populous city of Utah, United States. It is the county seat, seat of Salt Lake County, Utah, Sal ...
. He was a tenured professor of surgery - cardiothoracic at the University of Utah until December 2016.
Patel studied medicine at
Case Western Reserve University
Case Western Reserve University (CWRU) is a private research university in Cleveland, Ohio. Case Western Reserve was established in 1967, when Western Reserve University, founded in 1826 and named for its location in the Connecticut Western Reser ...
. In 2002, he led a "breakthrough" study demonstrating that
stem cell
In multicellular organisms, stem cells are undifferentiated or partially differentiated cells that can differentiate into various types of cells and proliferate indefinitely to produce more of the same stem cell. They are the earliest type o ...
transplantation could treat
congestive heart failure
Heart failure (HF), also known as congestive heart failure (CHF), is a syndrome, a group of signs and symptoms caused by an impairment of the heart's blood pumping function. Symptoms typically include shortness of breath, excessive fatigue, a ...
. He is currently the national lead investigator for Aastrom Biosciences now
Vericel Corp to treat
cardiomyopathy
Cardiomyopathy is a group of diseases that affect the heart muscle. Early on there may be few or no symptoms. As the disease worsens, shortness of breath, feeling tired, and swelling of the legs may occur, due to the onset of heart failure. A ...
both ischemic and non-ischemic using adult stem cells in the U.S. He just completed and published the largest heart failure trial for cell therapy in patients with ischemic heart failure. The trial was published in the journal ''Lancet'' and demonstrated a 37% reduction in death and hospitalizations for patients with severe heart failure. He is also the lead investigator for a number of trials to use adult stem cells to treat limb ischemia (inadequate blood flow to the leg). He has taught many surgeons around the world in countries such as
Thailand
Thailand ( ), historically known as Siam () and officially the Kingdom of Thailand, is a country in Southeast Asia, located at the centre of the Indochinese Peninsula, spanning , with a population of almost 70 million. The country is bo ...
and
India
India, officially the Republic of India (Hindi: ), is a country in South Asia. It is the seventh-largest country by area, the second-most populous country, and the most populous democracy in the world. Bounded by the Indian Ocean on the so ...
. Notable patients of his include
Hawaii
Hawaii ( ; haw, Hawaii or ) is a state in the Western United States, located in the Pacific Ocean about from the U.S. mainland. It is the only U.S. state outside North America, the only state that is an archipelago, and the only stat ...
an singer
Don Ho; Ho credited Patel's 2005 procedure on him with saving his life and allowing him to return to performing after being forced into retirement for health reasons. He is currently working on programs for
type 2 diabetes
Type 2 diabetes, formerly known as adult-onset diabetes, is a form of diabetes mellitus that is characterized by high blood sugar, insulin resistance, and relative lack of insulin. Common symptoms include increased thirst, frequent urination, ...
, burn wound therapies with the U.S. military & arteriocyte, traumatic brain injury, and plastic reconstruction. He has started collaborative programs in
Peru
, image_flag = Flag of Peru.svg
, image_coat = Escudo nacional del Perú.svg
, other_symbol = Great Seal of the State
, other_symbol_type = Seal (emblem), National seal
, national_motto = "Fi ...
,
Argentina
Argentina (), officially the Argentine Republic ( es, link=no, República Argentina), is a country in the southern half of South America. Argentina covers an area of , making it the second-largest country in South America after Brazil, th ...
,
Ecuador
Ecuador ( ; ; Quechua: ''Ikwayur''; Shuar: ''Ecuador'' or ''Ekuatur''), officially the Republic of Ecuador ( es, República del Ecuador, which literally translates as "Republic of the Equator"; Quechua: ''Ikwadur Ripuwlika''; Shuar: ''Eku ...
,
Germany
Germany,, officially the Federal Republic of Germany, is a country in Central Europe. It is the second most populous country in Europe after Russia, and the most populous member state of the European Union. Germany is situated betwe ...
, and India. His newest program is to treat heart failure patients with one-day outpatient cell therapies – harvest. Patel has recently developed a stem cell spray for rapid healing of heart surgery and burns. He is also the founder of Xogenex LLC, a gene therapy company for heart failure. The project is code-names the "Bourne-Project" because it has multiple genes to improve heart function which can be regulated and non-virally integrated into patients. He is also the co-founder of Jadi Cell LLC which involves a novel xenofree umbilical cord stem cell which is currently being used in a number of clinical trials.
Patel was involved in a retracted study, authored with
Mandeep R. Mehra
Mandeep R. Mehra (born December 1967 in Delhi) is The William Harvey Distinguished Chair in Advanced Cardiovascular Medicine and a professor of medicine at Harvard Medical School. He is the medical director of the Brigham Heart and Vascular Center ...
and
Sapan Desai
Sapan Sharankishor Desai (born April 6, 1979) is an American physician, and the owner of Surgisphere, originally a textbook marketing company that claimed to provide large sets of medical data. This data and the research using it has been discredi ...
, relating to using
hydroxychloroquine to treat
COVID-19
Coronavirus disease 2019 (COVID-19) is a contagious disease caused by a virus, the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The first known case was COVID-19 pandemic in Hubei, identified in Wuhan, China, in December ...
during the
COVID-19 pandemic
The COVID-19 pandemic, also known as the coronavirus pandemic, is an ongoing global pandemic of coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The novel virus was first identif ...
, which used suspect data from
Surgisphere
Surgisphere is an American healthcare analytics company established in 2008 by Sapan Desai. Originally a textbook marketing company, it came under scrutiny in May 2020 after it provided large datasets of COVID-19 patients that were subsequently ...
. It was published in ''
The Lancet
''The Lancet'' is a weekly peer-reviewed general medical journal and one of the oldest of its kind. It is also the world's highest-impact academic journal. It was founded in England in 1823.
The journal publishes original research articles, ...
'' which retracted it. He co-authored another COVID-19 study that also used suspect data from
Surgisphere
Surgisphere is an American healthcare analytics company established in 2008 by Sapan Desai. Originally a textbook marketing company, it came under scrutiny in May 2020 after it provided large datasets of COVID-19 patients that were subsequently ...
and which was retracted by ''
New England Journal of Medicine''. Patel and Desai are related by marriage. In June 2020 both journals retracted the study and the University of Utah terminated Patel's position over the papers. Upon further independent investigation, it was determined that it was Patel that called for the retraction of both papers as he could not verify the veracity of the Surgisphere program. He had also already verbally resigned from his volunteer position at the University of Utah long before the story in stat news.
Dr.
Richard Horton,
editor in chief
An editor-in-chief (EIC), also known as lead editor or chief editor, is a publication's editorial leader who has final responsibility for its operations and policies.
The highest-ranking editor of a publication may also be titled editor, managing ...
of ''The Lancet'', called the paper a fabrication and "a monumental fraud". Dr.
Eric Rubin
Eric J. Rubin is an American microbiologist, infectious disease specialist, and is currently the editor-in-chief of the ''New England Journal of Medicine''. He is also an adjunct professor of immunology and infectious diseases and was formerly th ...
, editor-in-chief of NEJM, said "we shouldn't have published this."
Additionally, Patel's University of Utah profile claimed 100 publications, nearly two-thirds of which he did not write but were co-authored by other individuals with the same surname.
References
{{DEFAULTSORT:Patel, Amit
University of Utah faculty
American people of Indian descent in health professions
Case Western Reserve University alumni
Living people
Year of birth missing (living people)
American cardiac surgeons
American people of Gujarati descent
Scientific misconduct incidents