Amikhelline is an
antimitotic
A mitotic inhibitor is a drug that inhibits mitosis, or cell division. These drugs disrupt microtubules, which are structures that pull the chromosomes apart when a cell divides. Mitotic inhibitors are used in cancer treatment, because cancer cell ...
drug. It acts as a
DNA intercalator
In biochemistry, intercalation is the insertion of molecules between the planar bases of deoxyribonucleic acid (DNA). This process is used as a method for analyzing DNA and it is also the basis of certain kinds of poisoning.
There are several ...
and inhibits
DNA polymerase
A DNA polymerase is a member of a family of enzymes that catalyze the synthesis of DNA molecules from nucleoside triphosphates, the molecular precursors of DNA. These enzymes are essential for DNA replication and usually work in groups to create ...
.
References
Antineoplastic and immunomodulating drugs
Benzofuran ethers at the benzene ring
Furanochromones
DNA intercalaters
DNA polymerase inhibitors
Diethylamino compounds
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