Alternative Vaccination Schedule
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In the United States, an alternative vaccination schedule is a
vaccination schedule A vaccination schedule is a series of vaccinations, including the timing of all doses, which may be either recommended or compulsory, depending on the country of residence. A vaccine is an antigenic preparation used to produce active immunity t ...
differing from the schedule endorsed by the
Advisory Committee on Immunization Practices The Advisory Committee on Immunization Practices (ACIP) is a National Immunization Technical Advisory Group, committee within the United States Centers for Disease Control and Prevention (CDC) that provides advice and guidance on effective control ...
(ACIP). These schedules may be either written or ''
ad hoc ''Ad hoc'' is a List of Latin phrases, Latin phrase meaning literally for this. In English language, English, it typically signifies a solution designed for a specific purpose, problem, or task rather than a Generalization, generalized solution ...
'', and have not been tested for their safety or efficacy. Proponents of such schedules aim to reduce the risk of adverse effects they believe to be caused by vaccine components, such as " immune system overload" that is argued to be caused by exposure to multiple
antigen In immunology, an antigen (Ag) is a molecule, moiety, foreign particulate matter, or an allergen, such as pollen, that can bind to a specific antibody or T-cell receptor. The presence of antigens in the body may trigger an immune response. ...
s. Parents who adopt these schedules tend to do so because they are concerned about the potential risks of vaccination, rather than because they are unaware of the significance of vaccination's benefits. Delayed vaccination schedules have been shown to lead to an increase in breakthrough infections without any benefit in lower side effect profiles.Kroger A, Bahta L, Hunter P
Best Practices Guidance of the Advisory Committee on Immunization Practices (ACIP)


Effects

Contrary to the claims made by some advocates of alternative vaccine schedules, there is no scientific evidence for the existence of "immune system overload", and according to the UK
National Health Service The National Health Service (NHS) is the term for the publicly funded health care, publicly funded healthcare systems of the United Kingdom: the National Health Service (England), NHS Scotland, NHS Wales, and Health and Social Care (Northern ...
the idea is a "myth". In addition, the amount of chemicals in vaccines such as
aluminium Aluminium (or aluminum in North American English) is a chemical element; it has chemical symbol, symbol Al and atomic number 13. It has a density lower than that of other common metals, about one-third that of steel. Aluminium has ...
and
formaldehyde Formaldehyde ( , ) (systematic name methanal) is an organic compound with the chemical formula and structure , more precisely . The compound is a pungent, colourless gas that polymerises spontaneously into paraformaldehyde. It is stored as ...
is much lower than natural exposure levels. Intentional deviation from the ACIP's schedule leaves children vulnerable to infection and increases the likelihood of outbreaks of vaccine-preventable diseases. These schedules also increase the chances of infection among individuals who could not be vaccinated for medical reasons, because they were too young, or who did not develop a sufficient immunologic response to the vaccine. After one of the most notorious outbreaks of
measles Measles (probably from Middle Dutch or Middle High German ''masel(e)'', meaning "blemish, blood blister") is a highly contagious, Vaccine-preventable diseases, vaccine-preventable infectious disease caused by Measles morbillivirus, measles v ...
in the
United States The United States of America (USA), also known as the United States (U.S.) or America, is a country primarily located in North America. It is a federal republic of 50 U.S. state, states and a federal capital district, Washington, D.C. The 48 ...
, in
California California () is a U.S. state, state in the Western United States that lies on the West Coast of the United States, Pacific Coast. It borders Oregon to the north, Nevada and Arizona to the east, and shares Mexico–United States border, an ...
, legislation was passed to make vaccination mandatory, as alternative vaccine scheduling and/or avoidance had been prevalent before the outbreak.


Popularity

An increasing number of children are undervaccinated, of whom an estimated 13% or more are believed to be so because of parental choice. One survey, published in ''Vaccine'', found that 9.4% of parents in
King County, Washington King County is a County (United States), county located in the U.S. state of Washington (state), Washington. The population was 2,269,675 in the 2020 United States census, 2020 census, making it the List of counties in Washington, most populo ...
used an alternative vaccine schedule, while another survey found that more than 1 out of 10 parents of children aged between 6 months and 6 years used an alternative vaccine schedule. In a 2011 survey of Washington State pediatricians, 77% of them reported that their patients "sometimes or frequently" asked for alternative vaccination schedules. The same survey found that 61% of pediatricians were comfortable with using such a schedule if a parent asked for it. A 2012 survey found that the percentage of shot-limiting children—defined as children who received no more than two vaccines per visit between their birth and the age of nine months—had increased from 2.5% to 9.5% in
Portland, Oregon Portland ( ) is the List of cities in Oregon, most populous city in the U.S. state of Oregon, located in the Pacific Northwest region. Situated close to northwest Oregon at the confluence of the Willamette River, Willamette and Columbia River, ...
. Research on well-off American families suggests that even parents who are ostensibly pro-vaccine can be misled by disinformation, and this can lead them to delay having their children vaccinated, and to tolerate such delay in others.


Proponents

Among the most prominent proponents of alternative vaccination schedules is notable pediatrician and vaccine critic Robert Sears. Sears has been criticized by vaccine expert Paul Offit for what Offit states is Sears' "misrepresentation of vaccine science." Offit argues that Sears' alternative vaccination schedules present a public health risk, in that Sear's alternative vaccination schedules require a larger number of visits to the doctors office for parents - and unvaccinated children can acquire transmissible diseases while waiting in doctors offices'. Furthermore, increasing the time before a child receives a vaccine will increase the time in which that child is vulnerable to contracting preventable diseases. Additionally, spreading out vaccination shots does not decrease a child's pain or anxiety related to the shot: in fact, increasing a child's total amount of doctor visits for vaccination shots (by insisting upon a single shot per visit) may increase that child's needle phobia, according to Dr. Offit. Overall, Sears' alternative vaccination schedules are likely to decrease immunization rates by reducing vaccine timeliness. Notably, Sears has responded to Offit's critique by conceding many of his original positions - in other words, Sears has since stated that he is in favour of the conventional vaccine schedule, and that many of his original positions (e.g., that thimerosal causes autism) are not supported by evidence. Likewise, the American Academy of Pediatricians has stated that no alternative vaccine schedules have been found to provide better safety or efficacy than the recommended vaccination schedule. In June 2018, the
Medical Board of California The Medical Board of California (MBC) is a state government agency which licenses and disciplines physicians, surgeons and certain allied healthcare professionals in California. The Board provides two principal types of services to consumers: (1 ...
placed Sears on probation for improperly granting a medical exemption from all future vaccines to a two-year-old child without obtaining any of the child's medical records, including which vaccines the child had received to date.


Types of schedules

A 2016 study identified five different types of alternative vaccine schedules: Sears' schedule, a shot-limiting schedule, selective delaying or refusal, making vaccine decisions visit-by-visit, or refusing all vaccines. Regardless of the type of alternative schedule used, skipping or delaying recommended vaccines has been shown to result in an increased risk of contracting and spreading
vaccine-preventable diseases A vaccine-preventable disease is an infectious disease for which an effective preventive vaccine exists. If a person acquires a vaccine-preventable disease and dies from it, the death is considered a vaccine-preventable death. The most common and ...
.


See also

* MMR vaccine and autism *
Vaccine hesitancy Vaccine hesitancy is a delay in acceptance, or refusal of vaccines despite availability and supporting evidence. The term covers refusals to vaccinate, delaying vaccines, accepting vaccines but remaining uncertain about their use, or using ce ...


References


Further reading

* {{Vaccine safety Vaccine hesitancy