α
Vβ
5 is a type of
integrin
Integrins are transmembrane receptors that facilitate cell-cell and cell-extracellular matrix (ECM) adhesion. Upon ligand binding, integrins activate signal transduction pathways that mediate cellular signals such as regulation of the cell cycle, ...
that binds to
matrix macromolecules
In biology, the extracellular matrix (ECM), also called intercellular matrix, is a Three-dimensional space, three-dimensional network consisting of extracellular macromolecules and minerals, such as collagen, enzymes, glycoproteins and hydroxyapa ...
and
proteinase
A protease (also called a peptidase, proteinase, or proteolytic enzyme) is an enzyme that catalyzes (increases reaction rate or "speeds up") proteolysis, breaking down proteins into smaller polypeptides or single amino acids, and spurring the ...
s and thereby stimulates
angiogenesis. However, it inhibits angiogenesis.
It consists of two components,
integrin alpha V and
integrin beta 5.
References
External links
*
{{Integrins
Integrins