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Almirall, S.A. is a Spanish
pharmaceutical company The pharmaceutical industry discovers, develops, produces, and markets drugs or pharmaceutical drugs for use as medications to be administered to patients (or self-administered), with the aim to cure them, vaccinate them, or alleviate sympt ...
, with headquarters in
Barcelona Barcelona ( , , ) is a city on the coast of northeastern Spain. It is the capital and largest city of the autonomous community of Catalonia, as well as the second most populous municipality of Spain. With a population of 1.6 million within ...
, founded in 1943. In 2016, it generated total revenue of €859.3 millionAlmirall: financial data 2016
/ref> and became the leading pharmaceutical company in R&D investment in Spain. With over 1,975 employees (2016), it has a presence, through its 13 affiliates in
Europe Europe is a large peninsula conventionally considered a continent in its own right because of its great physical size and the weight of its history and traditions. Europe is also considered a subcontinent of Eurasia and it is located enti ...
and United States.


History


Early history

Almirall SA was founded in 1943 in Spain. In 1979 the company launched gastroprokinetic clebopride in Spain, the first product from the company’s internal R&D team. In 1984 the business launched antacid product,
almagate Almagate (trade name Almax) is an aluminium- and magnesium-containing antacid. It was first described in 1984. Adverse effects Almagate is well tolerated. In a clinical trial, the most common adverse effects were diarrhea and nausea. Refe ...
, in Spain, as well as
anti-inflammatory Anti-inflammatory is the property of a substance or treatment that reduces inflammation or swelling. Anti-inflammatory drugs, also called anti-inflammatories, make up about half of analgesics. These drugs remedy pain by reducing inflammation as ...
piketoprofen in 1985 and antihistamine ebastine and cinitapride in 1985. In the same year, Almirall opened its first subsidiary, based in Belgium. In 1992 the company launched aceclofenac and a year later opened its second foreign subsidiary, in Portugal. The company's new headquarters were opened in Barcelona, in 1994. In 1997 Almirall and Prodesfarma merged their interests.


Further expansion

In 2000 the FDA approved anti-migraine agent almotriptan. A year later the company opened its Mexican subsidiary as well as acquiring its French affiliate. Beginning in 2002, Almirall opened a series of European based subsidiaries; Italy (2002), Germany (2003), Austria, Poland, the United Kingdom, Ireland and Switzerland (2008) and Nordic Countries (2010).https://www.almirall.com/documents/10876/119719/AF_Brochure_Corporativo_2019_EN.pdf/5f8965ba-03ef-90c8-ceb7-9432896c7113?t=1562607154615 In 2005 the business acquired the commercial rights for Sativex in
Europe Europe is a large peninsula conventionally considered a continent in its own right because of its great physical size and the weight of its history and traditions. Europe is also considered a subcontinent of Eurasia and it is located enti ...
for the treatment of spasticity associated to multiple sclerosis. In 2006, the company opened its new R&D Centre based in Sant Feliu de Llobregat as well as the acquisition of the Centre of Excellence for Inhalation Technology. In 2007 the company floated on the Spanish stock market, as well as acquiring European dermatology specialist, Hermal. The company also acquired a portfolio of eight products from Shire plc. In 2011 Almirall launched Actikerall prescribed for the local treatment of actinic keratosis. In 2012 Almirall opened its first North America subsidiary, based in Canada and launched aclidinium, prescribed for
chronic obstructive pulmonary disease Chronic obstructive pulmonary disease (COPD) is a type of progressive lung disease characterized by long-term respiratory symptoms and airflow limitation. The main symptoms include shortness of breath and a cough, which may or may not produce ...
(
COPD Chronic obstructive pulmonary disease (COPD) is a type of progressive lung disease characterized by long-term respiratory symptoms and airflow limitation. The main symptoms include shortness of breath and a cough, which may or may not produce ...
), in Europe under the brand Eklira Genuair and Bretaris Genuair and in the United States under the brand Tudorza Pressair. The business also launched Monovo, for the treatment of inflammatory skin diseases such as psoriasis. In 2013 Almirall acquired another specialist dermatology company, Aqua Pharmaceuticals. The company launched linaclotide in Europe (Constella) for
irritable bowel syndrome Irritable bowel syndrome (IBS) is a "disorder of gut-brain interaction" characterized by a group of symptoms that commonly include abdominal pain and or abdominal bloating and changes in the consistency of bowel movements. These symptoms ma ...
with
constipation Constipation is a bowel dysfunction that makes bowel movements infrequent or hard to pass. The stool is often hard and dry. Other symptoms may include abdominal pain, bloating, and feeling as if one has not completely passed the bowel moveme ...
(IBS-C) and opened its Netherlands subsidiary. In 2014 Almirall divested its rights to its respiratory franchise to Astrazeneca focussing on the dermatology, later in 2015 declaring its strategic intention to become a leading pharmaceutical company in the field of dermatology and continuing with its expansion by acquiring Poli Group Holding. In 2016 Almirall acquired ThermiGen LLC. In January 2020, the company announced it would acquire Bioniz Therapeutic. In 2020, Almirall earned 74.3 million euros, 30% less than the previous year. The following year it closed with a loss of 40.9 million. According to the annual accounts, the losses were justified by the accounting impairment of various products, although sales grew by 2.5%, driven by the dermatology business. In February 2022 it was announced that Carlos Gallardo would replace his father, Jorge Gallardo, as president of the company.


Activities

Almirall collaborates with various public and private entities, such as the Centro Superior de Investigaciones Científicas ( CSIC), the Instituto de Investigación Biomédica and the Parc Científic de Barcelona in Spain. Highlighted among the international alliances are those with the
Imperial College London Imperial College London (legally Imperial College of Science, Technology and Medicine) is a public research university in London, United Kingdom. Its history began with Prince Albert, consort of Queen Victoria, who developed his vision for a ...
(United Kingdom) and the
National Institute of Health The National Institutes of Health, commonly referred to as NIH (with each letter pronounced individually), is the primary agency of the United States government responsible for biomedical and public health research. It was founded in the late ...
( NIH) in the United States. Almirall participated in the creation of the Barcelona Respiratory Network Foundation.Barcelona Respiratory Network Foundation
/ref> In
Europe Europe is a large peninsula conventionally considered a continent in its own right because of its great physical size and the weight of its history and traditions. Europe is also considered a subcontinent of Eurasia and it is located enti ...
, the company has contributed in several projects with the
Innovative Medicines Initiative The Innovative Medicines Initiative (IMI) is a European initiative to improve the competitive situation of the European Union in the field of pharmaceutical research. The IMI is a joint initiative ( public-private partnership) of the DG Resear ...
(IMI).


Centres

The company has three R&D centres distributed in Spain and Germany (Reinbek) and Switzerland (Lugano). The R&D centre in Sant Feliu de Llobregat (
Barcelona Barcelona ( , , ) is a city on the coast of northeastern Spain. It is the capital and largest city of the autonomous community of Catalonia, as well as the second most populous municipality of Spain. With a population of 1.6 million within ...
), houses the departments involved in all stages of R&D, as well as the development of new chemical entities. The Reinbek Centre of Excellence for
Dermatology Dermatology is the branch of medicine dealing with the skin.''Random House Webster's Unabridged Dictionary.'' Random House, Inc. 2001. Page 537. . It is a speciality with both medical and surgical aspects. A List of dermatologists, dermatologist ...
specializes in the development of new formulas for the treatment of skin diseases. The company also has three production centres: two in Spain, the pharmaceutical plant in Sant Andreu de la Barca (
Barcelona Barcelona ( , , ) is a city on the coast of northeastern Spain. It is the capital and largest city of the autonomous community of Catalonia, as well as the second most populous municipality of Spain. With a population of 1.6 million within ...
) and the pharmaceutical and chemical plant in Sant Celoni (
Barcelona Barcelona ( , , ) is a city on the coast of northeastern Spain. It is the capital and largest city of the autonomous community of Catalonia, as well as the second most populous municipality of Spain. With a population of 1.6 million within ...
); and a pharmaceutical plant in Germany ( Reinbek); as well as 13 affiliates in Germany, Austria, Belgium-
Luxembourg Luxembourg ( ; lb, Lëtzebuerg ; french: link=no, Luxembourg; german: link=no, Luxemburg), officially the Grand Duchy of Luxembourg, ; french: link=no, Grand-Duché de Luxembourg ; german: link=no, Großherzogtum Luxemburg is a small land ...
, the United States, France, the
Netherlands ) , anthem = ( en, "William of Nassau") , image_map = , map_caption = , subdivision_type = Sovereign state , subdivision_name = Kingdom of the Netherlands , established_title = Before independence , established_date = Spanish Netherl ...
, Italy, the Nordic countries,
Poland Poland, officially the Republic of Poland, , is a country in Central Europe. Poland is divided into Voivodeships of Poland, sixteen voivodeships and is the fifth most populous member state of the European Union (EU), with over 38 mill ...
,
Portugal Portugal, officially the Portuguese Republic, In recognized minority languages of Portugal: :* mwl, República Pertuesa is a country located on the Iberian Peninsula, in Southwestern Europe, and whose territory also includes the Macaronesian ...
, the United Kingdom-Ireland, Spain and Switzerland.Almirall
What is the size of Almirall's overall workforce?
� Retrieved 30 July 2014


Numbers


Main products


References


External links

* {{IBEX 35 companies Biotechnology companies of Spain Pharmaceutical companies of Spain Manufacturing companies based in Barcelona Companies listed on the Madrid Stock Exchange Pharmaceutical companies established in 1943 1943 establishments in Spain Spanish brands Multinational companies headquartered in Spain