Allophanate Hydrolase
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In
enzymology An enzyme () is a protein that acts as a biological catalyst by accelerating chemical reactions. The molecules upon which enzymes may act are called substrate (chemistry), substrates, and the enzyme converts the substrates into different mol ...
, an allophanate hydrolase () is an
enzyme An enzyme () is a protein that acts as a biological catalyst by accelerating chemical reactions. The molecules upon which enzymes may act are called substrate (chemistry), substrates, and the enzyme converts the substrates into different mol ...
that
catalyzes Catalysis () is the increase in rate of a chemical reaction due to an added substance known as a catalyst (). Catalysts are not consumed by the reaction and remain unchanged after it. If the reaction is rapid and the catalyst recycles quick ...
the
chemical reaction A chemical reaction is a process that leads to the chemistry, chemical transformation of one set of chemical substances to another. When chemical reactions occur, the atoms are rearranged and the reaction is accompanied by an Gibbs free energy, ...
:allophanate + 3 H2O + H+ \rightleftharpoons 2 HCO3 + 2 NH4+ Thus, the two substrates of this enzyme are allophanate (urea-1-carboxylate or ''N''-carbamoylcarbamate) and H2O, whereas its two
products Product may refer to: Business * Product (business), an item that can be offered to a market to satisfy the desire or need of a customer. * Product (project management), a deliverable or set of deliverables that contribute to a business solution ...
are HCO3 and NH4+. This enzyme belongs to the family of
hydrolase In biochemistry, hydrolases constitute a class of enzymes that commonly function as biochemical catalysts that use water to break a chemical bond: :\ce \quad \xrightarrowtext\quad \ce This typically results in dividing a larger molecule into s ...
s, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in linear amides. The
systematic name A systematic name is a name given in a systematic way to one unique group, organism, object or chemical substance, out of a specific population or collection. Systematic names are usually part of a nomenclature. A semisystematic name or semitrivi ...
of this enzyme class is urea-1-carboxylate amidohydrolase. This enzyme is also called allophanate lyase. This enzyme participates in urea cycle and metabolism of amino groups and atrazine degradation.


See also

*
Urea carboxylase In enzymology, a urea carboxylase () is an enzyme that catalyzes the chemical reaction :ATP + urea + HCO3- \rightleftharpoons ADP + phosphate + urea-1-carboxylate The 3 substrates of this enzyme are ATP, urea, and HCO3-, whereas its 3 products ...


References

* * * * EC 3.5.1 Enzymes of unknown structure {{3.5-enzyme-stub