Align-m is a

multiple sequence alignment Multiple sequence alignment (MSA) is the process or the result of sequence alignment of three or more biological sequences, generally protein, DNA, or RNA. These alignments are used to infer evolutionary relationships via phylogenetic analysis an ...

program written by Ivo Van Walle. Align-m has the ability to accomplish the following tasks: * multiple sequence alignment, * include extra information to guide the sequence alignment, * multiple

structural alignment Structural alignment attempts to establish homology between two or more polymer structures based on their shape and three-dimensional conformation. This process is usually applied to protein tertiary structures but can also be used for large R ...

, *

homology modeling Homology modeling, also known as comparative modeling of protein, refers to constructing an atomic-resolution model of the "''target''" protein from its amino acid sequence and an experimental three-dimensional structure of a related homologous pr ...

by (iteratively) combining sequence and structure alignment data, * 'filtering' of BLAST or other pairwise alignments, * combining many alignments into one

consensus sequence In molecular biology and bioinformatics, the consensus sequence (or canonical sequence) is the calculated sequence of most frequent residues, either nucleotide or amino acid, found at each position in a sequence alignment. It represents the result ...

, * multiple genome alignment (can cope with rearrangements).

External links

Official website
Bioinformatics Computational_phylogenetics {{bioinformatics-stub

See also

External links