Alexander Rudensky (born August 21, 1956) is an immunologist at

Memorial Sloan Kettering Cancer Center Memorial Sloan Kettering Cancer Center (MSK or MSKCC) is a cancer treatment and research institution in Manhattan in New York City. MSKCC is one of 72 National Cancer Institute– designated Comprehensive Cancer Centers. Its main campus is ...

known for his research on

regulatory T cells The regulatory T cells (Tregs or Treg cells), formerly known as suppressor T cells, are a subpopulation of T cells that modulate the immune system, maintain immune tolerance, tolerance to self-antigens, and prevent autoimmune disease. Treg ...

and the

transcription factor In molecular biology, a transcription factor (TF) (or sequence-specific DNA-binding factor) is a protein that controls the rate of transcription (genetics), transcription of genetics, genetic information from DNA to messenger RNA, by binding t ...

Foxp3 FOXP3 (forkhead box P3), also known as scurfin, is a protein involved in immune system responses. A member of the FOX protein family, FOXP3 appears to function as a master regulator of the regulatory pathway in the development and function of r ...

Career

Rudensky received his

Candidate of Sciences A Candidate of Sciences is a Doctor of Philosophy, PhD-equivalent academic research degree in all the post-Soviet countries with the exception of Ukraine, and until the 1990s it was also awarded in Central and Eastern European countries. It is ...

degree in 1986 from the Gabrichevsky Research Institute of Epidemiology and Microbiology, Moscow, and completed his postdoctoral work at the

Yale School of Medicine The Yale School of Medicine is the medical school of Yale University, a private research university in New Haven, Connecticut. It was founded in 1810 as the Medical Institution of Yale College and formally opened in 1813. It is the sixth-oldest m ...

. He is now the Chair of the Immunology Program and Director of the Ludwig Center at Memorial Sloan Kettering, as well as a professor at the

Rockefeller University The Rockefeller University is a Private university, private Medical research, biomedical Research university, research and graduate-only university in New York City, New York. It focuses primarily on the biological and medical sciences and pro ...

Cornell University Cornell University is a Private university, private Ivy League research university based in Ithaca, New York, United States. The university was co-founded by American philanthropist Ezra Cornell and historian and educator Andrew Dickson W ...

, Gerstner School of Graduate Studies, and Weill-Cornell Medical School. In a 2003 paper, Rudensky and colleagues showed that Foxp3 programs regulatory T cell development. His lab continues to investigate the molecular mechanisms underlying regulatory T cell activity, and the role these cells play in autoimmunity, tumor immunity, and immunity to infections.

Awards

* 2012 Member of the

National Academy of Sciences The National Academy of Sciences (NAS) is a United States nonprofit, NGO, non-governmental organization. NAS is part of the National Academies of Sciences, Engineering, and Medicine, along with the National Academy of Engineering (NAE) and the ...

* 2015 Member of the

American Academy of Arts and Sciences The American Academy of Arts and Sciences (The Academy) is one of the oldest learned societies in the United States. It was founded in 1780 during the American Revolution by John Adams, John Hancock, James Bowdoin, Andrew Oliver, and other ...

* 2015

William B. Coley Award The William B. Coley Award for Distinguished Research in Basic and Tumor Immunology is presented annually by the Cancer Research Institute, to scientists who have made outstanding achievements in the fields of basic and tumor immunology and whose ...

* 2017

Crafoord Prize The Crafoord Prize () is an annual science prize established in 1980 by Holger Crafoord, a Swedish industrialist, and his wife Anna-Greta Crafoord following a donation to the Royal Swedish Academy of Sciences. It is awarded jointly by the Acade ...

in Polyarthritis * 2018

Vilcek Prize The Vilcek Foundation is an American nonprofit organization. The foundation's programs include the Vilcek Foundation Prizes. The Foundation was established in 2000 by Jan and Marica Vilcek, immigrants from the former Czechoslovakia. The missio ...

in Biomedical Science

References

External links

mskcc.org
* {{US-biologist-stub American microbiologists 1956 births Living people Yale School of Medicine alumni Members of the National Academy of Medicine