Alexander Davidovich Dilman () is a Russian organic chemist and is a professor of the Russian Academy of Sciences. Dilman currently is a Head of the Laboratory of Functional Organic Compounds at N. D. Zelinsky Institute of Organic Chemistry of the Russian Academy of Sciences (ZIOC RAS). Since 2022 he is a Corresponding Member of the Russian Academy of Sciences.

Biography

Dilman was born in Moscow in 1976. At the age of 15 he attended the Moscow Chemical Lyceum in order to deep dive in chemistry. In 1993 Dilman attended the Higher Chemical College of the Russian Academy of Sciences. During his undergraduate research he studied the chemistry of nitro- and

organosilicon compounds Organosilicon chemistry is the study of organometallic compounds containing carbon–silicon bonds, to which they are called organosilicon compounds. Most organosilicon compounds are similar to the ordinary organic compounds, being colourless, fl ...

at the ZIOC RAS under Vladimir Tartakovsky supervision. Dilman completed an internship in the group of at the Ludwig Maximilian University of Munich in 2000. The results he obtained in Germany became a part of his dissertation. In 2001 he defended his Ph.D. thesis on the topic "Chemistry of N,N-bis(silyloxy)enamines" under Prof. Sema Ioffe supervision. During a post-doctoral internship in Prof. Henri Kagan`s laboratory Dilman studied the chemistry of

rhodium Rhodium is a chemical element; it has symbol Rh and atomic number 45. It is a very rare, silvery-white, hard, corrosion-resistant transition metal. It is a noble metal and a member of the platinum group. It has only one naturally occurring isot ...

and

iridium Iridium is a chemical element; it has the symbol Ir and atomic number 77. This very hard, brittle, silvery-white transition metal of the platinum group, is considered the second-densest naturally occurring metal (after osmium) with a density ...

carbene complexes in 2002. Dilman began to work in the field of

organofluorine chemistry Organofluorine chemistry describes the chemistry of organofluorine compounds, organic compounds that contain a carbon–fluorine bond. Organofluorine compounds find diverse applications ranging from Lipophobicity, oil and hydrophobe, water repell ...

at ZIOC RAS in 2003. In 2008, he defended his Dr. Sci. dissertation connected with the development of new methods for the synthesis of fluorinated amines. In 2011 Dilman became the head of the Laboratory of Functional Organic Compounds at ZIOC RAS.

Research

Dilman's early works are related to the chemistry of silanes containing a perfluorinated group. There are studies on reactivity to

enamine An enamine is an unsaturated compound derived by the condensation of an aldehyde or ketone with a secondary amine. Enamines are versatile intermediates. The word "enamine" is derived from the affix ''en''-, used as the suffix of alkene, and the r ...

imine In organic chemistry, an imine ( or ) is a functional group or organic compound containing a carbon–nitrogen double bond (). The nitrogen atom can be attached to a hydrogen or an organic group (R). The carbon atom has two additional single bon ...

s, iminium salts N-benzoyl

hydrazone Hydrazones are a class of organic compounds with the structure . They are related to ketones and aldehydes by the replacement of the oxygen =O with the = functional group. They are formed usually by the action of hydrazine on ketones or aldehydes. ...

s. Significant part of the research is devoted to the introduction of a

trifluoromethyl The trifluoromethyl group is a functional group that has the formula . The naming of is group is derived from the methyl group (which has the formula ), by replacing each hydrogen atom by a fluorine atom. Some common examples are trifluoromethane ...

group by means of Ruppert-Prakash reagent, a difluoromethyl moiety from

difluorocarbene Difluorocarbene is the chemical compound with formula CF2. It has a short half-life, 0.5 and 20 ms, in solution and in the gas phase, respectively.Douglas A Jean Osteraas "Difluorocarbene Modification of Polymer and Fiber Surfaces," ''Journal ...

and transformations of α,α-difluorinated phosphonium salts. The development of methods for the introduction of CF₃– and CF₂H– groups is important for

medicinal chemistry Medicinal or pharmaceutical chemistry is a scientific discipline at the intersection of chemistry and pharmacy involved with drug design, designing and developing pharmaceutical medication, drugs. Medicinal chemistry involves the identification, ...

. Recently

photoredox catalysis Photoredox catalysis is a branch of photochemistry that uses electron transfer, single-electron transfer. Photoredox catalysts are generally drawn from three classes of materials: transition-metal complexes, organic dyes, and semiconductors. While ...

became the main research area of the Dilman group. Engaging visible light energy in chemical transformations allows many procedures to be more environmentally-friendly and widely available to organic chemists. Research of his group mainly connected with development of approaches for radical functionalization of alkenes,

s and radical C–H bonds activation. Other research directions are connected with the activation of carboxylic acids under

acridine Acridine is an organic compound and a nitrogen heterocycle with the formula C13H9N. Acridines are substituted derivatives of the parent ring. It is a planar molecule that is structurally related to anthracene with one of the central CH groups ...

photocatalytic conditions as well as photochemical transformations of polyfluorinated aryl sulfides.

Teaching

Since 2003 Dilman, together with William Smith, taught the course "Organic Synthesis" at ZIOC RAS. In 2009 he continued to lecture on this discipline together with his student V. V. Levin. Based on mentioned course the book co-authored with W. A. Smith was published in 2008.

Awards

* Diploma of the 1st degree of the 6th Mendeleev Competition of scientific research works of chemistry students (1995) * Medal of the Russian Academy of Sciences for Young Scientists (1999) (together with A. A. Tishkov). * Laureate of grants from the President of the Russian Federation to support young scientists * Laureate of the Foundation for the Promotion of National Science (2008) * Liebig Lecturer Award of the German Chemical Society (2019)

References

{{DEFAULTSORT:Dilman, Alexander 1976 births Living people Corresponding Members of the Russian Academy of Sciences Russian chemists