Aldo Castellani
   HOME

TheInfoList



OR:

Aldo Luigi Mario Castellani, Marchese di Chisimajo, KCMG (8 September 1874 – 3 October 1971) was an Italian
pathologist Pathology is the study of disease. The word ''pathology'' also refers to the study of disease in general, incorporating a wide range of biology research fields and medical practices. However, when used in the context of modern medical treatme ...
and
bacteriologist A bacteriologist is a microbiologist, or similarly trained professional, in bacteriology— a subdivision of microbiology that studies bacteria, typically Pathogenic bacteria, pathogenic ones. Bacteriologists are interested in studying and learnin ...
. He is best remembered as discoverer of the
etiology Etiology (; alternatively spelled aetiology or ætiology) is the study of causation or origination. The word is derived from the Greek word ''()'', meaning "giving a reason for" (). More completely, etiology is the study of the causes, origins ...
of
sleeping sickness African trypanosomiasis is an insect-borne parasitic infection of humans and other animals. Human African trypanosomiasis (HAT), also known as African sleeping sickness or simply sleeping sickness, is caused by the species '' Trypanosoma b ...
(with David Bruce, 1903) and
Yaws Yaws is a tropical infection of the skin, bones, and joints caused by the spirochete bacterium ''Treponema pallidum pertenue''. The disease begins with a round, hard swelling of the skin, in diameter. The center may break open and form an ulc ...
(1905), as a pioneer in the development and use of combined vaccines.


Life and achievements

Castellani was born in
Florence Florence ( ; ) is the capital city of the Italy, Italian region of Tuscany. It is also the most populated city in Tuscany, with 362,353 inhabitants, and 989,460 in Metropolitan City of Florence, its metropolitan province as of 2025. Florence ...
and educated there, qualifying in medicine in 1899. He worked for a time in
Bonn Bonn () is a federal city in the German state of North Rhine-Westphalia, located on the banks of the Rhine. With a population exceeding 300,000, it lies about south-southeast of Cologne, in the southernmost part of the Rhine-Ruhr region. This ...
and joined the School of Hygiene and Tropical Medicine in London in 1901. As bacteriologist with the Royal Society Commission on Sleeping Sickness in 1902, he went to
Entebbe Entebbe is a city in Central Region, Uganda, Central Uganda which is located on Lake Victoria peninsula, approximately southwest of the Ugandan capital city, Kampala. Entebbe was once the seat of government for the Protectorate of Uganda pri ...
, Uganda with George Carmichael Low and Cuthbert Christy. He demonstrated the cause and means of transmission of sleeping sickness, discovered the
spirochete A spirochaete () or spirochete is a member of the phylum Spirochaetota (also called Spirochaetes ), which contains distinctive diderm (double-membrane) Gram-negative bacteria, most of which have long, helically coiled (corkscrew-shaped or ...
of
yaws Yaws is a tropical infection of the skin, bones, and joints caused by the spirochete bacterium ''Treponema pallidum pertenue''. The disease begins with a round, hard swelling of the skin, in diameter. The center may break open and form an ulc ...
, and did other original work in bacteriology and in
parasitic Parasitism is a close relationship between species, where one organism, the parasite, lives (at least some of the time) on or inside another organism, the host, causing it some harm, and is adapted structurally to this way of life. The ent ...
diseases of the skin. In 1903 he was appointed Bacteriologist to the Government of
Ceylon Sri Lanka, officially the Democratic Socialist Republic of Sri Lanka, also known historically as Ceylon, is an island country in South Asia. It lies in the Indian Ocean, southwest of the Bay of Bengal, separated from the Indian subcontinent, ...
at the Central laboratory in
Colombo Colombo, ( ; , ; , ), is the executive and judicial capital and largest city of Sri Lanka by population. The Colombo metropolitan area is estimated to have a population of 5.6 million, and 752,993 within the municipal limits. It is the ...
and continued research in mycology and bacteriology, describing several new species of intestinal
bacilli Bacilli is a Taxonomy (biology), taxonomic Class (biology), class of bacteria that includes two orders, Bacillales and Lactobacillales, which contain several well-known pathogens such as ''Bacillus anthracis'' (the cause of anthrax). ''Bacilli'' ...
.Medical Research Institute, Sri Lanka
He invented the absorption test for the
serological Serology is the scientific study of serum and other body fluids. In practice, the term usually refers to the diagnostic identification of antibodies in the serum. Such antibodies are typically formed in response to an infection (against a given mi ...
identification of closely allied organisms. He left Ceylon in 1915 for
Naples Naples ( ; ; ) is the Regions of Italy, regional capital of Campania and the third-largest city of Italy, after Rome and Milan, with a population of 908,082 within the city's administrative limits as of 2025, while its Metropolitan City of N ...
where he took the Chair of Medicine. He was involved during
World War I World War I or the First World War (28 July 1914 – 11 November 1918), also known as the Great War, was a World war, global conflict between two coalitions: the Allies of World War I, Allies (or Entente) and the Central Powers. Fighting to ...
in Serbia and Macedonia as a member of the Inter-Allied Sanitary Commission. In 1919 Castellani went to London as Consultant to the
Ministry of Pensions The Ministry of Pensions was a British government ministry responsible for the administration and delivery of pensions. It was headed by the Minister of Pensions (Britain), Minister of Pensions. History In September 1916, a United Kingdom cabin ...
.CASTELLANI, Sir Aldo (1877–1971)
. London School of Hygiene and Tropical Medicine
He became lecturer on
mycology Mycology is the branch of biology concerned with the study of fungus, fungi, including their Taxonomy (biology), taxonomy, genetics, biochemistry, biochemical properties, and ethnomycology, use by humans. Fungi can be a source of tinder, Edible ...
and mycotic diseases at the
London School of Hygiene and Tropical Medicine The London School of Hygiene & Tropical Medicine (LSHTM) is a public university, public research university in Bloomsbury, central London, and a constituent college, member institution of the University of London that specialises in public hea ...
, and established a consulting practice in Harley Street. He was knighted in 1928 as an Honorary and in 1934 his daughter Jacqueline Castellani married Sir Miles Lampson. Castellani's enthusiasm for Royal and eminent patients such as
Benito Mussolini Benito Amilcare Andrea Mussolini (29 July 188328 April 1945) was an Italian politician and journalist who, upon assuming office as Prime Minister of Italy, Prime Minister, became the dictator of Fascist Italy from the March on Rome in 1922 un ...
clouded his reputation and during
World War II World War II or the Second World War (1 September 1939 – 2 September 1945) was a World war, global conflict between two coalitions: the Allies of World War II, Allies and the Axis powers. World War II by country, Nearly all of the wo ...
he supported Italy against the Allies, becoming chief of the Italian Army's medical service.
War correspondent A war correspondent is a journalist who covers stories first-hand from a war, war zone. War correspondence stands as one of journalism's most important and impactful forms. War correspondents operate in the most conflict-ridden parts of the wor ...
Alaric Jacob Harold Alaric Jacob (8 June 1909 – 26 January 1995) was an English writer and journalist. He was a Reuters correspondent in Washington in the 1930s and a war correspondent during World War II in North Africa, Burma and Moscow. Early life Ala ...
discovered his looted quarters in Cirene in December 1941 and was tempted to pass his correspondence to his son in law Sir Miles Lampson, then British Ambassador in Egypt. Castellani was President of the International Society of Dermatology from 1960 to 1964, which he had founded in 1959. He was also professor of tropical medicine at the State University of Louisiana and also at the Royal University of Rome. He followed the Queen of Italy Marie José into exile in Portugal and ended his life as Professor at
Lisbon Lisbon ( ; ) is the capital and largest city of Portugal, with an estimated population of 567,131, as of 2023, within its administrative limits and 3,028,000 within the Lisbon Metropolitan Area, metropolis, as of 2025. Lisbon is mainlan ...
's Institute of Tropical Medicine. Castellani died in 1971. Castellani's paint (
Carbol fuchsin Carbol fuchsin, carbol-fuchsin, carbolfuchsin, or Castellani's paint is a mixture of phenol and basic fuchsin that is used in bacterial staining procedures. It is commonly used in the staining of mycobacteria because it has an affinity for the my ...
solution) is still occasionally used to treat fungal skin infections. The human pathogen
Acanthamoeba ''Acanthamoeba'' is a genus of amoeboid, amoebae that are commonly recovered from soil, fresh water, and other habitat (ecology), habitats. The genus ''Acanthamoeba'' has two stages in its life cycle, the metabolically active trophozoite stage a ...
castellanii is named after him.


Literary works

* ''Manual of tropical medicine'', 1910 (with Albert John Chalmers); 2nd edition, 1913; * ''Fungi and fungous diseases'', 1928 * ''Climate and acclimatisation'', 1938 * ''Manuale di clinica tropicale'', (with Jacono) * ''Microbes, Men and Monarchs: A Doctor's Life in Many Lands: The Autobiography of Aldo Castellani'' Victor Gollancz LTD (1963)


References


Bibliography

* Anonymous, "Aldo Castellani (Obituary)", The British Medical Journal, 16 October 1971, p. 175 * Binazzi, Maurizio, "Italian Memoirs of Aldo Castellani", International Journal of Dermatology, vol. 30, n. 10 (October 1991), pp. 741–5 * Borghi, Luca. ''The Globetrotter of Medicine: The life and times of Aldo Castellani (1874-1971)'', Amazon KDP, 2025, pp. 650, ISBN 979-8325992148 * Borghi, Luca, Riva, Elisabetta, "Was Aldo Castellani the inventor of combined and polyvalent vaccines?", Vaccine, 39 (2021), pp. 5442–5446 * Borghi, Luca, "Man Who Won the War": Myth and Reality of Aldo Castellani's Role in Preserving the Health of Troops During the Italo-Ethiopian War 1935–1936, Adv Exp Med Biol, 2022 Jul 26. Online ahead of print. https://doi.org/10.1007/5584_2022_737 * Bosco, G., "Ricordo di Aldo Castellani", Rivista Italiana d'Igiene, vol. 62 (2003), nn. 1–2, pp. 1–17 * Cambournac, Francisco J.C., "Professor Sir Aldo Castellani", Anais da Escola Nacional de Saude Publica e de Medicina Tropical, vol. 5, nn. 3-4 (Julho-Dezembro 1971), pp. 377–383 * Cipollaro, Vincent A., "Euphoria et cacophoria - anecdotes, reminiscences and controversies of Aldo Castellani; and 'who let Castellani go'?", International Journal of Dermatology, 2007, 46, 439–442 * Cook, Gordon C., "Aldo Castellani FRCP (1877-1971) and the founding of the Ross Institute & Hospital for Tropical Diseases at Putney", J Med Biog 2000: 8, 198–205 * Garnham, Percy Cyril C., "Aldo Castellani 1877-1971", Commentarii Pontificia Academia Scientiarum, vol. 2 (1972), n. 45, pp. 1–35 * Ito, Kasuke, "A Synopsis of the Life of Aldo Castellani", International Journal of Dermatology, vol. 11, n. 4 (oct-dec 1972), pp. 192–6 * Parish, Lawrence Charles, "Reflections on Aldo Castellani and Tropical Dermatology", Trans R Soc Trop Med Hyg, 2018 Apr 1;112(4):155-157 * Raffaele, Giulio, Aldo Castellani. Discorso commemorativo pronunciato dal Linceo Giulio Raffaele nella Seduta ordinaria del 14 aprile 1973, Accademia Nazionale dei Lincei, Roma 1973, pp. 17 * Rho, Filippo, "Glorie e figure della Medicina Italiana: Aldo Castellani", Estratto da La Medicina Italiana (n. 7, luglio 1922), pp. 8 * Sebastiani, Antonio, Serarcangeli, Carla, "Aldo Castellani (1874-1971). Un viaggio scientifico lungo un secolo", Medicina nei Secoli, 2003;15(3):469-500 * Seeliger, H.P.R., Seefried, L., "Aldo Castellani - an Appraisal of his Life and Oeuvre", Mycoses, 15 May 1989, 32(8), pp. 391–397 * Vanbreuseghem, Raymond, "Notice sur la vie et l'oeuvre du Professeur Aldo Castellani, Membre honoraire étranger (8 septembre 1874 – 3 octobre 1971)", Bull. Acad. Mèd. Belg., 128 (1973), pp. 69–78 * W.F.D.-C., "Aldo Castellani (Obituary)",
The Lancet ''The Lancet'' is a weekly peer-reviewed general medical journal, founded in England in 1823. It is one of the world's highest-impact academic journals and also one of the oldest medical journals still in publication. The journal publishes ...
, 16 October 1971, p. 883


External links


Biography
on Whonamedit
National Portrait Gallery collection

Some places and memories related to Aldo Castellani on Himetop – The History of Medicine Topographical Database
{{DEFAULTSORT:Castellani, Aldo 1874 births 1971 deaths Italian exiles Italian monarchists Italian pathologists Italian bacteriologists Italian expatriates in Portugal Honorary Knights Commander of the Order of St Michael and St George Physicians from Florence Italian expatriates in the United Kingdom Expatriates in British Ceylon 20th-century Italian nobility Members of the Senate of the Kingdom of Italy