Alain Frédéric Carpentier (born 11 August 1933) is a French
cardiac surgeon whom the President of the
American Association for Thoracic Surgery
The American Association for Thoracic Surgery (AATS) is an international association of cardiothoracic surgeons. It was founded in 1917 by the earliest pioneers in the field of thoracic surgery. Headquartered in Beverly, Massachusetts, it has ove ...
calls the "father of modern
mitral valve repair
Mitral valve repair is a cardiac surgery procedure performed by cardiac surgeons to treat stenosis (narrowing) or regurgitation (leakage) of the mitral valve. The mitral valve is the "inflow valve" for the left side of the heart. Blood flows f ...
". He is most well-known for the development and popularization of a number of mitral valve repair techniques. In 1996, he performed the first minimally invasive
mitral valve repair
Mitral valve repair is a cardiac surgery procedure performed by cardiac surgeons to treat stenosis (narrowing) or regurgitation (leakage) of the mitral valve. The mitral valve is the "inflow valve" for the left side of the heart. Blood flows f ...
in the world and in 1998 he performed the first robotic
mitral valve repair
Mitral valve repair is a cardiac surgery procedure performed by cardiac surgeons to treat stenosis (narrowing) or regurgitation (leakage) of the mitral valve. The mitral valve is the "inflow valve" for the left side of the heart. Blood flows f ...
with the
da Vinci Surgical System
The da Vinci Surgical System is a robotic surgical system that uses a minimally invasive surgical approach. The system is manufactured by the company Intuitive Surgical. The system is used for prostatectomies, increasingly for cardiac valve ...
prototype. He is the recipient of the 2007
Lasker Prize.
Biography
He received his MD from the
University of Paris
The University of Paris (), known Metonymy, metonymically as the Sorbonne (), was the leading university in Paris, France, from 1150 to 1970, except for 1793–1806 during the French Revolution. Emerging around 1150 as a corporation associated wit ...
in 1966 and his PhD from the same university in 1975. A
professor emeritus
''Emeritus/Emerita'' () is an honorary title granted to someone who retirement, retires from a position of distinction, most commonly an academic faculty position, but is allowed to continue using the previous title, as in "professor emeritus".
...
at
Pierre and Marie Curie University
Pierre and Marie Curie University ( , UPMC), also known as Paris VI, was a public research university in Paris, France, from 1971 to 2017. The university was located on the Jussieu Campus in the Latin Quarter of the 5th arrondissement of Paris, ...
, in the 1980s Carpentier published a landmark paper on mitral valve repair entitled ''The French Correction''. A visiting professor at
Mount Sinai School of Medicine
The Icahn School of Medicine at Mount Sinai (ISMMS or Mount Sinai), formerly the Mount Sinai School of Medicine, is a private medical school in New York City, New York, United States. The school is the academic teaching arm of the Mount Sina ...
in New York City, he currently heads the Department of
Cardiovascular Surgery at the
Hôpital Européen Georges-Pompidou
The Hôpital Européen Georges-Pompidou (, ''Georges Pompidou European Hospital'', abbr. HEGP) is a French hospital located in Paris.
The HEGP is under the aegis of the Assistance publique - Hôpitaux de Paris (AP-HP).
Opened in 2001, the HEGP i ...
in Paris. In 1986, he and
Gilles Dreyfus
Gilles Dreyfus (born 24 May 1951) is a French cardiac surgeon.
Education
Gilles Dreyfus graduated from the Medical Faculty of Paris (Paris V, CHU Broussais – Hotel Dieu). From 1978 to 1983 he was Resident in cardiac surgery at the Hôpitau ...
performed the first
artificial heart
An artificial heart is a artificial organ, device that replaces the human heart, heart. Artificial hearts are typically used as a bridge to heart transplantation, but ongoing research aims to develop a device that could permanently replace the ...
implant in Europe.
Carpentier is a member of the
French Academy of Sciences
The French Academy of Sciences (, ) is a learned society, founded in 1666 by Louis XIV at the suggestion of Jean-Baptiste Colbert, to encourage and protect the spirit of French Scientific method, scientific research. It was at the forefron ...
and sits on the
Board of Directors
A board of directors is a governing body that supervises the activities of a business, a nonprofit organization, or a government agency.
The powers, duties, and responsibilities of a board of directors are determined by government regulatio ...
of the
World Heart Foundation. The recipient of numerous awards, including the 1996
Prix mondial Cino Del Duca
The Prix mondial Cino Del Duca (Cino Del Duca World Prize) is an international literary award from France. With an award amount of , it is among the richest literary prizes.
Origins and operations
It was established in 1969 in France by French b ...
, in 2005 the
American Association for Thoracic Surgery
The American Association for Thoracic Surgery (AATS) is an international association of cardiothoracic surgeons. It was founded in 1917 by the earliest pioneers in the field of thoracic surgery. Headquartered in Beverly, Massachusetts, it has ove ...
(AATS) bestowed its ''Medallion for Scientific Achievement'' for only the fifth time in its history. In announcing Carpentier as the recipient, the AATS also noted that he is "one of the foremost medical
philanthropist
Philanthropy is a form of altruism that consists of "private initiatives for the public good, focusing on quality of life". Philanthropy contrasts with business initiatives, which are private initiatives for private good, focusing on material ...
s in the world, having established a premier cardiac center in Vietnam a decade ago where over 1,000 open-heart cases are now performed annually. In addition, he has founded cardiac surgery programs in 17 French-speaking countries in Africa."
In October 2001, he received an Honorary Doctor of Medicine and Surgery degree from
University of Pavia
The University of Pavia (, UNIPV or ''Università di Pavia''; ) is a university located in Pavia, Lombardy, Italy. There was evidence of teaching as early as 1361, making it one of the List of oldest universities in continuous operation, oldest un ...
.
In 2006, Carpentier received considerable media attention in the United States as the surgeon who performed an emergency mitral valve repair procedure on
Charlie Rose
Charles Peete Rose Jr. (born January 5, 1942) is an American journalist and talk show host. From 1991 to 2017, he was the host and executive producer of the talk show ''Charlie Rose (talk show), Charlie Rose'' on PBS and Bloomberg L.P., Bloombe ...
when the
PBS
The Public Broadcasting Service (PBS) is an American public broadcaster and non-commercial, free-to-air television network based in Arlington, Virginia. PBS is a publicly funded nonprofit organization and the most prominent provider of educat ...
television interviewer fell ill while en route to
Damascus
Damascus ( , ; ) is the capital and List of largest cities in the Levant region by population, largest city of Syria. It is the oldest capital in the world and, according to some, the fourth Holiest sites in Islam, holiest city in Islam. Kno ...
to interview Syrian president
Bashar al-Assad
Bashar al-Assad (born 11September 1965) is a Syrian politician, military officer and former dictator
Sources characterising Assad as a dictator:
who served as the president of Syria from 2000 until fall of the Assad regime, his government ...
.
In 1989, Carpentier pioneered work to use the patient's own
skeletal muscle
Skeletal muscle (commonly referred to as muscle) is one of the three types of vertebrate muscle tissue, the others being cardiac muscle and smooth muscle. They are part of the somatic nervous system, voluntary muscular system and typically are a ...
(the latimissus dorsi muscle) to repair the failing myocardium, a procedure known as
cardiomyoplasty
Cardiomyoplasty is a surgical procedure in which healthy muscle from another part of the body is wrapped around the heart to provide support for the failing heart. Most often the latissimus dorsi muscle is used for this purpose. A special pacemak ...
, which has since advanced into the exciting realms of tissue engineering science. In 2008, Carpentier announced a fully implantable
artificial heart
An artificial heart is a artificial organ, device that replaces the human heart, heart. Artificial hearts are typically used as a bridge to heart transplantation, but ongoing research aims to develop a device that could permanently replace the ...
will be ready for clinical trial by 2011, and for alternative to transplant in 2013. It was developed and will be manufactured by him, Biomedical firm Carmat, and venture capital firm
Truffle
A truffle is the Sporocarp (fungi), fruiting body of a subterranean ascomycete fungus, one of the species of the genus ''Tuber (fungus), Tuber''. More than one hundred other genera of fungi are classified as truffles including ''Geopora'', ''P ...
. The prototype uses electronic sensors and is made from chemically treated animal tissues, called "biomaterials," or a "pseudo-skin" of biosynthetic, microporous materials, amid another US team's prototype called 2005 MagScrew Total Artificial Heart, and Japan and South Korea researchers are racing to produce similar projects.
The first clinical trial are under process since 2013.
From 2009 to 2012, Carpentier was vice-president and then president of the
French Academy of Sciences
The French Academy of Sciences (, ) is a learned society, founded in 1666 by Louis XIV at the suggestion of Jean-Baptiste Colbert, to encourage and protect the spirit of French Scientific method, scientific research. It was at the forefron ...
.
Publications
*Alain Carpentier, David Adams and Farzan Filsoufi (2010). ''Carpentier's reconstructive valve surgery''. Missouri: Saunders Elsevier. 368 pp. . Illustrated by Alain Carpentier and Marcia Williams.
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Honors
*Honorary degree,
University of Pavia
The University of Pavia (, UNIPV or ''Università di Pavia''; ) is a university located in Pavia, Lombardy, Italy. There was evidence of teaching as early as 1361, making it one of the List of oldest universities in continuous operation, oldest un ...
, 2001
Notes
References
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{{DEFAULTSORT:Carpentier, Alain
1933 births
Living people
French surgeons
20th-century French philanthropists
Academic staff of the University of Paris
Members of the French Academy of Sciences
Commanders of the Legion of Honour
Commanders of the National Order of the Cedar
Recipients of the Lasker–DeBakey Clinical Medical Research Award
21st-century French philanthropists