Alacrima refers to an abnormality in tear production that could mean reduced tear production or absent tear production. Because a lack of tears presents in only in a few rare disorders, it aids in diagnosis of these disorders, including

Triple-A syndrome Triple-A syndrome or AAA syndrome is a rare autosomal recessive congenital disorder. In most cases, there is no family history of AAA syndrome. The syndrome was first identified by Jeremy Allgrove and colleagues in 1978; since then just over 100 ...

and

NGLY1 deficiency NGLY1 deficiency is a very rare genetic disorder caused by autosomal recessive, biallelic pathogenic mutation, variants in ''NGLY1''. It is an autosomal recessive disorder. Errors in glycosylation, deglycosylation are responsible for the symptoms ...

. Alacrima can be formally diagnosed through a

Schirmer's test Schirmer's test determines whether the human eye, eye produces enough tears to keep it moist. This test is used when a person experiences very dry eyes or excessive watering of the eyes. It can cause damage to the cornea. A negative (more than 10& ...

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Disorders of conjunctiva {{symptom-stub