Aildenafil (methisosildenafil) is a synthetic
drug
A drug is any chemical substance other than a nutrient or an essential dietary ingredient, which, when administered to a living organism, produces a biological effect. Consumption of drugs can be via insufflation (medicine), inhalation, drug i ...
that is a
structural analog
A structural analog, also known as a chemical analog or simply an analog, is a chemical compound, compound having a chemical structure, structure similar to that of another compound, but differing from it in respect to a certain component.
It can ...
of
sildenafil
Sildenafil, sold under the brand name Viagra among others, is a medication used to treat erectile dysfunction and pulmonary hypertension, pulmonary arterial hypertension. It is also sometimes used off-label for the treatment of certain sym ...
(Viagra). It was first reported in 2003. Like sildenafil, aildenafil is a
phosphodiesterase type 5 inhibitor.
Aildenafil has been found as an
adulterant
An adulterant is a substance secretly added to another that may compromise the safety or effectiveness. Typical substances that are adulterated include food, cosmetics, pharmaceuticals or fuels.
Definition
Adulteration is the practice of secre ...
in a variety of supplements which are sold as "natural" or "herbal" sexual enhancement products. The
United States Food and Drug Administration
The United States Food and Drug Administration (FDA or US FDA) is a List of United States federal agencies, federal agency of the United States Department of Health and Human Services, Department of Health and Human Services. The FDA is respo ...
has warned consumers that any sexual enhancement product that claims to work as well as prescription products is likely to contain such a contaminant.
Aildenafil is approved for use in China.
See also
*
Acetildenafil
Acetildenafil (hongdenafil) is a synthetic drug which acts as a phosphodiesterase inhibitor. It is an structural analog, analog of sildenafil (Viagra) which has been detected in numerous different brands of "herbal aphrodisiac" products sold in c ...
*
Nitrosoprodenafil
Nitrosoprodenafil is a synthetic designer drug found in "herbal" aphrodisiac products, which is a novel nitrosated analogue of sildenafil (Viagra). It has an innovative structure which acts as a prodrug, breaking down in the body to release both ...
*
Sulfoaildenafil
Sulfoaildenafil (thioaildenafil) is a synthetic drug that is a structural analog of sildenafil (Viagra). It was first reported in 2005, and it is not approved by any health regulation agency. Like sildenafil, sulfoaildenafil is a phosphodiester ...
References
{{Phosphodiesterase inhibitors
Designer drugs
PDE5 inhibitors
Sulfonamides