Adenophostin A is a potent

inositol trisphosphate Inositol trisphosphate or inositol 1,4,5-trisphosphate abbreviated InsP3 or Ins3P or IP3 is an inositol phosphate signaling molecule. It is made by hydrolysis of phosphatidylinositol 4,5-bisphosphate (PIP2), a phospholipid that is located in the ...

(IP₃)

receptor agonist An agonist is a chemical that activates a receptor to produce a biological response. Receptors are cellular proteins whose activation causes the cell to modify what it is currently doing. In contrast, an antagonist blocks the action of the agon ...

, but is much more potent than IP₃. IP₃R is a ligand-gated intracellular Ca²⁺ release channel that plays a central role in modulating

cytoplasm The cytoplasm describes all the material within a eukaryotic or prokaryotic cell, enclosed by the cell membrane, including the organelles and excluding the nucleus in eukaryotic cells. The material inside the nucleus of a eukaryotic cell a ...

ic free Ca²⁺ concentration (Ca²⁺i). Adenophostin A is structurally different from IP₃ but could elicit distinct calcium signals in cells.

References

Purines Organophosphates Signal transduction {{organic-compound-stub