Adele Kay Fielding is a British physician-scientist who is a Professor of Haematology at

University College London University College London (Trade name, branded as UCL) is a Public university, public research university in London, England. It is a Member institutions of the University of London, member institution of the Federal university, federal Uni ...

. Fielding was President of the

British Society for Haematology The British Society for Haematology is a Charitable organization, registered charity founded in 1960 for professionals specialising in hematology, haematology, the medical specialism covering blood disorders including cancers. Apart from represent ...

from 2020 until 2022.

Early life and education

Fielding was a medical student at

. She was a trainee in

haematology Hematology ( spelled haematology in British English) is the branch of medicine concerned with the study of the cause, prognosis, treatment, and prevention of diseases related to blood. It involves treating diseases that affect the production ...

(the medical specialty covering blood disorders including cancer) and general medicine in London. She moved to the Medical Research Council laboratory in

Cambridge Cambridge ( ) is a List of cities in the United Kingdom, city and non-metropolitan district in the county of Cambridgeshire, England. It is the county town of Cambridgeshire and is located on the River Cam, north of London. As of the 2021 Unit ...

for her doctoral research, and completed her doctorate in 1999.

Research and career

In 1999, Fielding was appointed assistant professor at the

Mayo Clinic Mayo Clinic () is a Nonprofit organization, private American Academic health science centre, academic Medical centers in the United States, medical center focused on integrated health care, healthcare, Mayo Clinic College of Medicine and Science ...

. She returned to the

United Kingdom The United Kingdom of Great Britain and Northern Ireland, commonly known as the United Kingdom (UK) or Britain, is a country in Northwestern Europe, off the coast of European mainland, the continental mainland. It comprises England, Scotlan ...

in 2003, where she joined

, becoming Professor of Haematology, and the

Royal Free Hospital The Royal Free Hospital (also known as the Royal Free) is a major teaching hospital in the Hampstead area of the London Borough of Camden. The hospital is part of the Royal Free London NHS Foundation Trust, which also runs services at Barnet Ho ...

for clinical practice. She moved clinical practice to

University College London Hospitals NHS Foundation Trust University College London Hospitals NHS Foundation Trust (UCLH) is an NHS foundation trust based in London, United Kingdom. It comprises University College Hospital, University College Hospital at Westmoreland Street, the UCH Macmillan Cancer C ...

in 2015, where she worked in the

leukemia Leukemia ( also spelled leukaemia; pronounced ) is a group of blood cancers that usually begin in the bone marrow and produce high numbers of abnormal blood cells. These blood cells are not fully developed and are called ''blasts'' or '' ...

service. In 2023, she moved to the

University of York The University of York (abbreviated as or ''York'' for Post-nominal letters, post-nominals) is a public Collegiate university, collegiate research university in York, England. Established in 1963, the university has expanded to more than thir ...

, where she is a Professor of Haematology and Head of Experimental Biomedicine at the

Hull York Medical School Hull York Medical School (HYMS) is a medical school in England which took its first intake of students in 2003. It was opened as a part of the British government's attempts to train more doctors, along with Brighton and Sussex Medical School, P ...

. She is also the Clinical Director of the University of York Centre for Blood Research. She currently sees patients at the Queens Centre, Castle Hill Hospital, Hull. Her research efforts look to improve the lives of people with

acute lymphoblastic leukemia Acute lymphoblastic leukemia (ALL) is a cancer of the Lymphocyte, lymphoid line of blood cells characterized by the development of large numbers of lymphoblast, immature lymphocytes. Symptoms may include feeling tired, pale skin color, fever, ...

(ALL). She is part of several clinical trials into ALL, which include studying the underlying mechanisms and searching for new treatments. Fielding has developed an attenuated oncolytic measles virus that can be used as a treatment of ALL. Fielding was elected President of the

in 2020 and was succeeded in 2022 by Josh Wright.

Selected publications

* * * *Burt R, Dey A, Aref S, Aguiar M, Akarca A, Bailey K, Day W, Hooper S, Kirkwood A, Kirschner K, Lee SW, Lo Celso C, Manji J, Mansour MR, Marafioti T, Mitchell RJ, Muirhead RC, Cheuk Yan Ng K, Pospori C, Puccio I, Zuborne-Alapi K, Sahai E, Fielding AK. Activated stromal cells transfer mitochondria to rescue acute lymphoblastic leukemia cells from oxidative stress. Blood. 2019 Oct 24;134(17):1415-1429. doi: 10.1182/blood.2019001398. PMID 31501154; PMCID: PMC6856969. * Marks DI, Kirkwood AA, Rowntree CJ, Aguiar M, Bailey KE, Beaton B, Cahalin P, Castleton AZ, Clifton-Hadley L, Copland M, Goldstone AH, Kelly R, Lawrie E, Lee S, McMillan AK, McMullin MF, Menne TF, Mitchell RJ, Moorman AV, Patel B, Patrick P, Smith P, Taussig D, Yallop D, Alapi KZ, Fielding AK. Addition of four doses of rituximab to standard induction chemotherapy in adult patients with precursor B-cell acute lymphoblastic leukaemia (UKALL14): a phase 3, multicentre, randomised controlled trial. Lancet Haematol. 2022 Apr;9(4):e262-e275. doi: 10.1016/S2352-3026(22)00038-2. PMID 35358441; PMCID: PMC8969057.

References

External links

* {{DEFAULTSORT:Fielding, Adele Living people 20th-century British medical doctors 21st-century British medical doctors 21st-century British women medical doctors British haematologists Alumni of University College London Alumni of the University of Cambridge Year of birth missing (living people) Presidents of the British Society for Haematology