
Acroosteolysis is resorption of the
distal
Standard anatomical terms of location are used to unambiguously describe the anatomy of animals, including humans. The terms, typically derived from Latin or Greek roots, describe something in its standard anatomical position. This position pro ...
bony
phalanges
The phalanges (singular: ''phalanx'' ) are digital bones in the hands and feet of most vertebrates. In primates, the thumbs and big toes have two phalanges while the other digits have three phalanges. The phalanges are classed as long bones.
...
. Acroosteolysis has two patterns of
resorption in adults: diffuse and bandlike.
The diffuse pattern of resorption has a widely diverse
differential diagnosis
In healthcare, a differential diagnosis (abbreviated DDx) is a method of analysis of a patient's history and physical examination to arrive at the correct diagnosis. It involves distinguishing a particular disease or condition from others that p ...
which includes:
pyknodysostosis,
collagen vascular disease and
vasculitis,
Raynaud's neuropathy, trauma,
epidermolysis bullosa,
psoriasis,
frostbite,
sarcoidosis,
hypertrophic osteoarthropathy,
acromegaly
Acromegaly is a disorder that results from excess growth hormone (GH) after the growth plates have closed. The initial symptom is typically enlargement of the hands and feet. There may also be an enlargement of the forehead, jaw, and nose. Other ...
, and advanced
leprosy.
[Yu, Joseph. Musculoskeletal Imaging, Case Review Series. 2008.]
The bandlike pattern of resorption may be seen with
polyvinyl chloride exposure and
Hadju-Cheney syndrome.
A mnemonic commonly used for acro-osteolysis is PINCHFO.
[http://radiopaedia.org/articles/pinch-fo ]
Pyknodysostosis, Psoriasis,
Injury (thermal burn, frostbite),
Neuropathy (
diabetes),
Collagen vascular disease (
scleroderma, Raynaud's),
Hyperparathyroidism,
Familial (Hadju-Cheney,
progeria),
Occupational (polyvinyl exposure),
Acroosteolysis may be associated with minimal skin changes or with
ischemic skin lesions that may result in digital
necrosis
Necrosis () is a form of cell injury which results in the premature death of cells in living tissue by autolysis. Necrosis is caused by factors external to the cell or tissue, such as infection, or trauma which result in the unregulated dige ...
.
[Freedberg, et al. (2003). ''Fitzpatrick's Dermatology in General Medicine''. (6th ed.). McGraw-Hill. .]
See also
*
Nail anatomy
References
Conditions of the skin appendages
Medical mnemonics
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