AZD9164 is an experimental drug that acts as a potent and selective antagonist of the

Muscarinic acetylcholine receptor M3 The muscarinic acetylcholine receptor, also known as cholinergic/acetylcholine receptor M3, or the muscarinic 3, is a muscarinic acetylcholine receptor encoded by the human gene CHRM3. The M3 muscarinic receptors are located at many places in ...

. It contains a quaternary nitrogen atom with a permanent positive charge and so is always encountered as a salt, usually paired with a bromide. It has been investigated for the treatment of

Chronic obstructive pulmonary disease Chronic obstructive pulmonary disease (COPD) is a type of progressive lung disease characterized by chronic respiratory symptoms and airflow limitation. GOLD defines COPD as a heterogeneous lung condition characterized by chronic respiratory s ...

(COPD) and reached phase II human clinical trials but did not progress to further development, however it is still used for research into the M3 receptor and its function.

References

Experimental drugs 4-Fluorophenyl compounds Piperidines Quaternary ammonium compounds Esters {{respiratory-system-drug-stub