A16A Other alimentary tract and metabolism products

A16AA
Amino acid Amino acids are organic compounds that contain both amino and carboxylic acid functional groups. Although hundreds of amino acids exist in nature, by far the most important are the alpha-amino acids, which comprise proteins. Only 22 alpha ...
s and derivatives

:A16AA01

Levocarnitine Carnitine is a quaternary ammonium compound involved in metabolism in most mammals, plants, and some bacteria. In support of energy metabolism, carnitine transports long-chain fatty acids into mitochondria to be oxidized for energy production ...

:A16AA02

Ademetionine ''S''-Adenosyl methionine (SAM), also known under the commercial names of SAMe, SAM-e, or AdoMet, is a common cosubstrate involved in methyl group transfers, transsulfuration, and aminopropylation. Although these anabolic reactions occur throu ...

:A16AA03

Levoglutamide Glutamine (symbol Gln or Q) is an α-amino acid that is used in the biosynthesis of proteins. Its side chain is similar to that of glutamic acid, except the carboxylic acid group is replaced by an amide. It is classified as a charge-neutra ...

:A16AA04

Mercaptamine Cysteamine is a chemical compound that can be biosynthesized in mammals, including humans, by the degradation of coenzyme A. The intermediate pantetheine is broken down into cysteamine and pantothenic acid. It is the biosynthetic precursor to ...

:A16AA05

Carglumic acid Carglumic acid, sold under the brand name Carbaglu among others, is used for the treatment of hyperammonaemia. Carglumic acid is a carbamoyl phosphate synthetase 1 (CPS 1) activator. The most common adverse effects include vomiting, abdominal pa ...

:A16AA06

Betaine A betaine () in chemistry is any neutral chemical compound with a positively charged cationic functional group, such as a quaternary ammonium or phosphonium cation (generally: onium ions) that bears no hydrogen atom and with a negatively char ...

:A16AA07 Metreleptin :QA16AA51 Levocarnitine, combinations

A16AB
Enzyme Enzymes () are proteins that act as biological catalysts by accelerating chemical reactions. The molecules upon which enzymes may act are called substrate (chemistry), substrates, and the enzyme converts the substrates into different molecule ...
s

:A16AB01

Alglucerase Alglucerase was a biopharmaceutical drug for the treatment of Gaucher's disease. It was a modified form of human β-glucocerebrosidase enzyme, where the non-reducing ends of the oligosaccharide chains have been terminated with mannose residues. ...

:A16AB02

Imiglucerase Imiglucerase is a medication used in the treatment of Gaucher's disease. It is a recombinant DNA-produced analogue of the human enzyme β-glucocerebrosidase. Cerezyme is a freeze-dried medicine containing imiglucerase, manufactured by Genzyme Co ...

:A16AB03 Agalsidase alfa :A16AB04 Agalsidase beta :A16AB05

Laronidase Iduronidase (, ''L-iduronidase'', ''alpha-L-iduronidase'', ''laronidase''), sold as Aldurazyme, is an enzyme with the systematic name ''glycosaminoglycan alpha-L-iduronohydrolase''. This enzyme catalyses the hydrolysis of unsulfated alpha-L-idu ...

:A16AB06 Sacrosidase :A16AB07

Alglucosidase alfa Alglucosidase alfa, sold under the brand name Myozyme among others, is an enzyme replacement therapy (ERT) orphan drug for treatment of Pompe disease (Glycogen storage disease type II), a rare lysosomal storage disorder (LSD). Chemically speaki ...

:A16AB08

Galsulfase Arylsulfatase B (N-acetylgalactosamine-4-sulfatase, chondroitinsulfatase, chondroitinase, acetylgalactosamine 4-sulfatase, N-acetylgalactosamine 4-sulfate sulfohydrolase, ) is an enzyme associated with mucopolysaccharidosis VI (Maroteaux– ...

:A16AB09 Idursulfase :A16AB10

Velaglucerase alfa Velaglucerase alfa, sold under the brand name Vpriv and manufactured by Shire plc, is a hydrolytic lysosomal glucocerebroside-specific enzyme, which is a recombinant form of glucocerebrosidase indicated as a long-term enzyme replacement therapy ...

:A16AB11

Taliglucerase alfa Taliglucerase alfa, sold under the brand name Elelyso among others, is a biopharmaceutical medication developed by Protalix and Pfizer. The drug, a recombinant glucocerebrosidase used to treat Gaucher's disease, is the first plant-made pharmaceut ...

:A16AB12 Elosulfase alfa :A16AB13 Asfotase alfa :A16AB14

Sebelipase alfa Sebelipase alfa, sold under the brand name Kanuma, is a recombinant form of the enzyme lysosomal acid lipase (LAL) that is used as a medication for the treatment of lysosomal acid lipase deficiency (LAL-D). Text was copied from this source ...

:A16AB15 Velmanase alfa :A16AB16 Idursulfase beta :A16AB17 Cerliponase alfa :A16AB18 Vestronidase alfa :A16AB19

Pegvaliase Pegvaliase, sold under the brand name Palynziq, is a medication for the treatment of the genetic disease phenylketonuria. Chemically, it is a pegylated derivative of the enzyme phenylalanine ammonia-lyase that metabolizes phenylalanine Pheny ...

:A16AB20 Pegunigalsidase alfa :A16AB21

Atidarsagene autotemcel Atidarsagene autotemcel, sold under the brand name Libmeldy, is a gene therapy treatment for metachromatic leukodystrophy (MLD) developed by Orchard Therapeutics. It contains an autologous CD34⁺ cell enriched population that contains haemato ...

:A16AB22 Avalglucosidase alfa :A16AB23

Cipaglucosidase alfa Cipaglucosidase alfa, sold under the brand name Pombiliti, and used in combination with miglustat, is a medication used for the treatment of glycogen storage disease type II (Pompe disease). Cipaglucosidase alfa is a recombinant human acid � ...

:A16AB24

Pegzilarginase Pegzilarginase, sold under the brand name Loargys, is a medication used for the treatment of hyperargininemia. The most common side effects include allergic reactions. Pegzilarginase was approved for medical use in the European Union in De ...

:A16AB25

Olipudase alfa Olipudase alfa, sold under the brand name Xenpozyme, is a medication used for the treatment of non-central nervous system (CNS) manifestations of acid sphingomyelinase deficiency (ASMD) type A/B or type B. Text was copied from this source which ...

A16AX Various alimentary tract and metabolism products

:A16AX01 Thioctic acid :A16AX02

Anethole trithione Anethole trithione, anetholtrithione, or anetholtrithion ( JAN) is a drug used in the treatment of dry mouth. It is listed in the U.S. National Cancer Institute's ''Dictionary of Cancer Terms'' as being studied in the treatment of cancer.

:A16AX03

Sodium phenylbutyrate Sodium phenylbutyrate, sold under the brand name Buphenyl among others, is a salt of an aromatic fatty acid, 4-phenylbutyrate (4-PBA) or 4-phenylbutyric acid. The compound is used to treat urea cycle disorders, because its metabolites offer an ...

:A16AX04 Nitisinone :A16AX05

Zinc acetate Zinc acetate is a salt with the formula Zn(CH3CO2)2, which commonly occurs as the dihydrate Zn(CH3CO2)2·2H2O. Both the hydrate and the anhydrous forms are colorless solids that are used as dietary supplements. When used as a food additive, it h ...

:A16AX06

Miglustat Miglustat, sold under the brand name Zavesca, is a medication used to treat type I Gaucher disease (GD1). It is also known as N-butyldeoxynojirimycin, and is a derivative of the anti-diabetic 1-deoxynojirimycin. It was developed by Oxford GlycoS ...

:A16AX07 Sapropterin :A16AX08

Teduglutide Teduglutide (brand names Gattex in the US and Revestive in Europe) is a 33-membered polypeptide and glucagon-like peptide-2 (GLP-2) analog that is used for the treatment of short bowel syndrome. It works by promoting mucosal growth and possibly r ...

:A16AX09 Glycerol phenylbutyrate :A16AX10

Eliglustat Eliglustat, sold under the brand name Cerdelga, is a medication used for the treatment of Gaucher's disease. It was discovered at the University of Michigan, developed by Genzyme Corp, and was approved by the FDA in August 2014. Commonly used as ...

:A16AX11

Sodium benzoate Sodium benzoate is the sodium salt of benzoic acid, widely used as a food preservative (with an E number of E211) and a pickling agent. It appears as a white crystalline chemical with the formula C6H5COONa. Production Sodium benzoate is commo ...

:A16AX12

Trientine Triethylenetetramine (TETA and trien), also known as trientine (INN) when used medically, is an organic compound with the formula H2NHCH2CH2NH2sub>2. The pure freebase is a colorless oily liquid, but, like many amines, older samples assume a yel ...

:A16AX13 Uridine triacetate :A16AX14

Migalastat Migalastat, sold under the brand name Galafold, is a medication for the treatment of Fabry disease, a rare genetic disorder. It was developed by Amicus Therapeutics. The US Food and Drug Administration (FDA) granted it orphan drug status in 2004, ...

:A16AX15

Telotristat Telotristat ethyl ( USAN, brand name Xermelo) is a prodrug of telotristat, which is an inhibitor of tryptophan hydroxylase. It is formulated as telotristat etiprate — a hippurate salt of telotristat ethyl. On February 28, 2017, the U.S. Foo ...

:A16AX16

Givosiran Givosiran, sold under the brand name Givlaari, is a medication used for the treatment of adults with acute hepatic porphyria. Givosiran is a small interfering RNA (siRNA) directed towards delta-aminolevulinate synthase 1 (ALAS1), an important ...

:A16AX17

Triheptanoin Triheptanoin, sold under the brand name Dojolvi, is a medication for the treatment of children and adults with molecularly confirmed long-chain fatty acid oxidation disorders (LC-FAOD). The most common adverse reactions include abdominal pain, d ...

:A16AX18 Lumasiran :A16AX19

Fosdenopterin Fosdenopterin (or cyclic pyranopterin monophosphate, cPMP), sold under the brand name Nulibry, is a medication used to reduce the risk of death due to a rare genetic disease known as molybdenum cofactor deficiency type A. The most common sid ...

:A16AX20 Lonafarnib :A16AX21 Elivaldogene autotemcel :A16AX22

Tiomolibdic acid Tiomolibdic acid (trade name Decuprate) is a chelating agent under investigation for the treatment of cancer and of Wilson's disease, a rare and potentially fatal disease in which the body cannot regulate copper. It is developed by Wilson T ...

:A16AX30 Sodium benzoate and sodium phenylacetate

QA16Q Other alimentary tract and metabolism products for veterinary use

QA16QA Drugs for prevention and/or treatment of acetonemia

:QA16QA01

Propylene glycol Propylene glycol ( IUPAC name: propane-1,2-diol) is a viscous, colorless liquid, which is nearly odorless but possesses a faintly sweet taste. Its chemical formula is CH3CH(OH)CH2OH. Containing two alcohol groups, it is classed as a diol. It ...

:QA16QA02

Sodium propionate Sodium propanoate or sodium propionate is the sodium salt of propionic acid which has the chemical formula Na( C2 H5 C O O). This white crystalline solid is deliquescent in moist air. Reactions It is produced by the reaction of propionic acid a ...

:QA16QA03

Glycerol Glycerol (), also called glycerine in British English and glycerin in American English, is a simple triol compound. It is a colorless, odorless, viscous liquid that is sweet-tasting and non-toxic. The glycerol backbone is found in lipids know ...

:QA16QA04

Ammonium lactate Ammonium lactate is a Compound (chemistry), compound with formula NH4(C2H4(OH)COO). It is the ammonium salt of lactic acid. It has mild anti-bacterial properties. It has E number "E328" and is the active ingredient of the skin lotions Amlactin a ...

:QA16QA05 Clanobutin :QA16QA06 Monensin :QA16QA52 Sodium propionate, combinations

References

{{Other alimentary tract and metabolism products A16