Putative Polycomb group protein ASXL3 is a
protein
Proteins are large biomolecules and macromolecules that comprise one or more long chains of amino acid residue (biochemistry), residues. Proteins perform a vast array of functions within organisms, including Enzyme catalysis, catalysing metab ...
that in
human
Humans (''Homo sapiens'') or modern humans are the most common and widespread species of primate, and the last surviving species of the genus ''Homo''. They are Hominidae, great apes characterized by their Prehistory of nakedness and clothing ...
s is encoded by the ''ASXL3''
gene
In biology, the word gene has two meanings. The Mendelian gene is a basic unit of heredity. The molecular gene is a sequence of nucleotides in DNA that is transcribed to produce a functional RNA. There are two types of molecular genes: protei ...
.
See also
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Bainbridge–Ropers syndrome
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Polycomb-group proteins
Polycomb-group proteins (PcG proteins) are a family of protein complexes first discovered in fruit flies that can remodel chromatin such that epigenetic silencing of genes takes place. Polycomb-group proteins are well known for silencing Hox genes ...
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ASXL1
Putative Polycomb group protein ASXL1 is a protein that in humans is encoded by the ''ASXL1'' gene.
In ''Drosophila'', the Additional sex combs (Asx) gene encodes a chromatin-binding protein required for normal determination of segment identity i ...
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ASXL2
Additional sex combs like 2, transcriptional regulator is a protein that in humans is encoded by the ''ASXL2'' gene.
Function
This gene encodes a member of a family of epigenetic regulators that bind various histone-modifying enzymes and are ...
References
Further reading
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Genes on human chromosome 18
{{gene-18-stub