Anaphase-promoting complex subunit 5 is an
enzyme
An enzyme () is a protein that acts as a biological catalyst by accelerating chemical reactions. The molecules upon which enzymes may act are called substrate (chemistry), substrates, and the enzyme converts the substrates into different mol ...
that in humans is encoded by the ''ANAPC5''
gene
In biology, the word gene has two meanings. The Mendelian gene is a basic unit of heredity. The molecular gene is a sequence of nucleotides in DNA that is transcribed to produce a functional RNA. There are two types of molecular genes: protei ...
.
The anaphase-promoting complex (APC) consists of at least 8 protein subunits, including APC5, CDC27 (APC3; MIM 116946), CDC16 (APC6; MIM 603461), and CDC23 (APC8; MIM 603462).
upplied by OMIMref name="entrez" />
Interactions
ANAPC5 has been shown to
interact
Advocates for Informed Choice, dba interACT or interACT Advocates for Intersex Youth, is a 501(c)(3) nonprofit organization advocating for the legal and human rights of children with intersex traits. The organization was founded in 2006 and fo ...
with
ANAPC1
Anaphase-promoting complex subunit 1 is an enzyme that in humans is encoded by the ''ANAPC1'' gene.
ANAPC1 is one of at least ten subunits of the anaphase-promoting complex (APC), which functions at the metaphase-to- anaphase transition of the ...
,
ANAPC4
Anaphase-promoting complex subunit 4 is an enzyme that in humans is encoded by the ''ANAPC4'' gene.
A large protein complex, termed the anaphase-promoting complex (APC), or the cyclosome, promotes metaphase-anaphase transition by ubiquitinating ...
,
[ ]CDC27
Cell division cycle protein 27 homolog is a protein that in humans is encoded by the ''CDC27'' gene.
Function
The protein encoded by this gene shares strong similarity with ''Saccharomyces cerevisiae'' protein Cdc27, and the gene product of '' ...
PABPC1
Polyadenylate-binding protein 1 is a protein that in humans is encoded by the ''PABPC1'' gene. The protein PABP1 binds mRNA and facilitates a variety of functions such as transport into and out of the nucleus, degradation, translation, and stabil ...
.[
]
References
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