Acetyl-CoA acetyltransferase, cytosolic, also known as cytosolic acetoacetyl-CoA thiolase, is an
enzyme
An enzyme () is a protein that acts as a biological catalyst by accelerating chemical reactions. The molecules upon which enzymes may act are called substrate (chemistry), substrates, and the enzyme converts the substrates into different mol ...
that in
human
Humans (''Homo sapiens'') or modern humans are the most common and widespread species of primate, and the last surviving species of the genus ''Homo''. They are Hominidae, great apes characterized by their Prehistory of nakedness and clothing ...
s is encoded by the ''ACAT2'' (acetyl-Coenzyme A acetyltransferase 2)
gene
In biology, the word gene has two meanings. The Mendelian gene is a basic unit of heredity. The molecular gene is a sequence of nucleotides in DNA that is transcribed to produce a functional RNA. There are two types of molecular genes: protei ...
Acetyl-Coenzyme A acetyltransferase 2 is an
acetyl-CoA C-acetyltransferase enzyme.
Gene
This gene shows complementary
overlapping with the
3-prime region of the
TCP1
In humans, the gene T-complex 1, a.k.a. TCP1, encodes the protein TCP-1, a.k.a. T-complex protein 1 subunit alpha.
Function
This gene encodes a molecular chaperone that is a member of the TRiC complex. This complex consists of two identical sta ...
gene in both
mouse
A mouse (: mice) is a small rodent. Characteristically, mice are known to have a pointed snout, small rounded ears, a body-length scaly tail, and a high breeding rate. The best known mouse species is the common house mouse (''Mus musculus'' ...
and human. These genes are encoded on opposite strands of
DNA
Deoxyribonucleic acid (; DNA) is a polymer composed of two polynucleotide chains that coil around each other to form a double helix. The polymer carries genetic instructions for the development, functioning, growth and reproduction of al ...
, as well as in opposite
transcriptional orientation
Directionality, in molecular biology and biochemistry, is the end-to-end chemical orientation of a single strand of nucleic acid. In a single strand of DNA or RNA, the chemical convention of naming carbon atoms in the nucleotide pentose-sugar-ri ...
.
References
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Human proteins
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