A. Carl Leopold
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Aldo Carl Leopold (December 18, 1919 – November 18, 2009) was an American academic and plant physiologist, son of Aldo Leopold, a noted ecologist. He is known for his research on soybeans which led to techniques allowing insulin to be dried and later processed into an inhalable insulin.


Early life and education

Aldo Carl Leopold was born to Aldo Leopold, a noted ecologist and employee of the
United States Forest Service The United States Forest Service (USFS) is an agency within the United States Department of Agriculture, U.S. Department of Agriculture. It administers the nation's 154 United States National Forest, national forests and 20 United States Natio ...
, and Estella Leopold in Albuquerque,
New Mexico New Mexico is a state in the Southwestern United States, Southwestern region of the United States. It is one of the Mountain States of the southern Rocky Mountains, sharing the Four Corners region with Utah, Colorado, and Arizona. It also ...
as the 4th of 5 children.


Career

Leopold received a bachelor's degree in botany from the
University of Wisconsin A university () is an institution of tertiary education and research which awards academic degrees in several academic disciplines. ''University'' is derived from the Latin phrase , which roughly means "community of teachers and scholars". Uni ...
in 1941. He enlisted in the Marines during World War II and served in the Pacific as defense counsel in courts-martial for soldiers who were charged with being AWOL. After his discharge, Leopold received MS and PhD degrees in plant physiology from
Harvard University Harvard University is a Private university, private Ivy League research university in Cambridge, Massachusetts, United States. Founded in 1636 and named for its first benefactor, the History of the Puritans in North America, Puritan clergyma ...
, studying under Kenneth Thimann. He worked briefly for the Hawaiian Pineapple Company, and then joined the faculty of
Purdue University Purdue University is a Public university#United States, public Land-grant university, land-grant research university in West Lafayette, Indiana, United States, and the flagship campus of the Purdue University system. The university was founded ...
in 1949. In 1975, he was appointed Graduate Dean and Assistant Vice President for Research at the
University of Nebraska A university () is an educational institution, institution of tertiary education and research which awards academic degrees in several Discipline (academia), academic disciplines. ''University'' is derived from the Latin phrase , which roughly ...
. In 1977, Leopold moved to the Boyce Thompson Institute for Plant Research (BTI) in Ithaca, New York as William H. Crocker Scientist. He is known for being a pioneer in the study of the plant hormone auxin, and later for work on desiccation tolerance in seeds and gravitropism. He is the author, with Paul Kriedemann, of a widely used textbook on plant growth and development. Seeds such as soybeans containing very high levels of
protein Proteins are large biomolecules and macromolecules that comprise one or more long chains of amino acid residue (biochemistry), residues. Proteins perform a vast array of functions within organisms, including Enzyme catalysis, catalysing metab ...
can undergo
desiccation Desiccation is the state of extreme dryness, or the process of extreme drying. A desiccant is a hygroscopic (attracts and holds water) substance that induces or sustains such a state in its local vicinity in a moderately sealed container. The ...
, yet survive and revive after water absorption. Leopold began studying this capability at BTI in the mid-1980s. He found soybeans and corn to have a range of soluble
carbohydrate A carbohydrate () is a biomolecule composed of carbon (C), hydrogen (H), and oxygen (O) atoms. The typical hydrogen-to-oxygen atomic ratio is 2:1, analogous to that of water, and is represented by the empirical formula (where ''m'' and ''n'' ...
s protecting the seed's cell viability by forming a glassy state rather than drying completely. Patents were awarded to him in the early 1990s on techniques for protecting "biological membranes" and proteins in the dry state. Using the knowledge gleaned from studying the preservation of proteins in dry soybeans, Leopold developed a method to preserve peptide hormones like insulin in the glassy state so that they can be pulverized into a powder and inhaled by diabetics as an alternative to self-injection. His research on soybeans led to techniques that allowed insulin to be dried and later processed into an inhalable insulin, named Exubera by Pfizer.


Personal life and death

Leopold was active in science and environmental issues from his retirement in 1990 until his death in 2009. Leopold, along with Ed Oyer, Thomas Eisner, Jim McConkey and Mary Woodson, was a founding member of the ''Preposthumous Society'' who together founded Greensprings Natural Cemetery Preserve. Leopold was the first member of the society to use it. He was the founding president of the Finger Lakes Land Trust in 1989, to preserve wild lands in the Finger Lakes region of New York. He founded the Tropical Forestry Initiative in 1993, which developed new methods to restore tropical forest from grazing lands in Costa Rica, and remained active until 2015. He was cofounder of the Aldo Leopold Society in 1982 to help people explore and apply Aldo Leopold's land ethic.


References


Works

*''Auxins and Plant Growth'' (1955, 1960) *''Plant Growth and Development'' (1964, 1975)


External links


Obituary Lansing StarUSFS film "Green Fire" on life and legacy of Aldo Leopold, father of CarlEulogy
given December 13, 2009 by Randy Wayne (biologist)
Finger Lakes Land TrustTropical Forestry Initiative
{{DEFAULTSORT:Leopold, A. Carl 1919 births 2009 deaths Purdue University faculty American people of German descent 21st-century American botanists American plant physiologists American textbook writers Harvard University alumni University of Wisconsin–Madison alumni University of Nebraska–Lincoln faculty