Downie bodies, also known as a type of A-type inclusion, are a type of inclusion body (protein aggregates) associated with

cowpox Cowpox is an infectious disease caused by Cowpox virus (CPXV). It presents with large blisters in the skin, a fever and swollen glands, historically typically following contact with an infected cow, though in the last several decades more often ...

. They are named for

Allan Watt Downie Allan Watt Downie FRS (5 September 1901 – 26 January 1988) was a Scottish microbiologist involved in the eradication of smallpox. He was elected a Fellow of the Royal Society Fellowship of the Royal Society (FRS, ForMemRS and HonFRS) is a ...

. A Downie body is different from a ''Downey cell'' which is a

reactive lymphocyte In immunology, reactive lymphocytes, variant lymphocytes, atypical lymphocytes, Downey cells or Türk cells are cytotoxic (CD8+) lymphocytes that become large as a result of antigen stimulation. Typically, they can be more than 30 μm in dia ...

. They are named for Hal Downey.

References

Viral diseases Histopathology {{Protein-stub