5,''N'',''N''-trimethyltryptamine (5,''N'',''N''-TMT; 5-TMT) is a
tryptamine
Tryptamine is an indolamine metabolite of the essential amino acid tryptophan. The chemical structure is defined by an indole—a fused benzene and pyrrole ring, and a 2-aminoethyl group at the second carbon (third aromatic atom, with the firs ...
derivative
In mathematics, the derivative is a fundamental tool that quantifies the sensitivity to change of a function's output with respect to its input. The derivative of a function of a single variable at a chosen input value, when it exists, is t ...
that is a
psychedelic
Psychedelics are a subclass of hallucinogenic drugs whose primary effect is to trigger non-ordinary mental states (known as psychedelic experiences or "trips") and a perceived "expansion of consciousness". Also referred to as classic halluci ...
drug. It was first made in 1958 by Edwin H. P. Young. In animal experiments it was found to be in between
DMT
Dimethyltryptamine (DMT), also known as ''N'',''N''-dimethyltryptamine (''N'',''N''-DMT), is a serotonergic hallucinogen and investigational drug of the tryptamine family that occurs naturally in many plants and animals, including humans. D ...
and
5-MeO-DMT
5-MeO-DMT (5-methoxy-''N'',''N''-dimethyltryptamine), also known as ''O''-methylbufotenin or mebufotenin (), is a naturally occurring psychedelic of the tryptamine family. It is found in a wide variety of plant species, and is also secreted by ...
in potency
which would suggest an active dosage for humans in the 20–60 mg range. Human psychoactivity for this compound has been claimed in reports on websites such as
Erowid
Erowid, also called Erowid Center, is a non-profit educational organization that provides information about psychoactive plants and chemicals.
Erowid documents legal and illegal substances, including their intended and adverse effects. Inform ...
but has not been independently confirmed.
Legal Status
United States
5,N,N-TMT is not scheduled at the federal level in the
United States
The United States of America (USA), also known as the United States (U.S.) or America, is a country primarily located in North America. It is a federal republic of 50 U.S. state, states and a federal capital district, Washington, D.C. The 48 ...
,
but it could be considered an analog of
5-MeO-DMT
5-MeO-DMT (5-methoxy-''N'',''N''-dimethyltryptamine), also known as ''O''-methylbufotenin or mebufotenin (), is a naturally occurring psychedelic of the tryptamine family. It is found in a wide variety of plant species, and is also secreted by ...
, in which case, sales or possession intended for human consumption could be prosecuted under the
Federal Analog Act
The Federal Analogue Act, , is a section of the United States Controlled Substances Act passed in 1986 which allows any chemical "substantially similar" to a controlled substance listed in Schedule I or II to be treated as if it were listed ...
.
See also
*
2,N,N-TMT
2,''N,N''-Trimethyltryptamine (2,''N,N''-TMT), also known as 2-methyl-''N'',''N''-dimethyltryptamine (2-Me-DMT), is a tryptamine derivative. It is not a psychedelic, but instead produces tactile enhancement and auditory distortion. The drug w ...
*
7,N,N-TMT
7,''N'',''N''-trimethyltryptamine (7-methyl-DMT, 7-TMT), is a tryptamine derivative which acts as an agonist of 5-HT2 receptors. In animal tests, both 7-TMT and its 5-methoxy derivative 5-MeO-7-TMT produced behavioural responses similar to those ...
*
5-Chloro-DMT
5-Chloro-''N'',''N''-dimethyltryptamine (5-chloro-DMT or 5-Cl-DMT) is a tryptamine derivative related to compounds such as 5-bromo-DMT and 5-fluoro-DMT. It acts as a serotonin receptor agonist and has primarily sedative effects in animal studie ...
*
5-Ethyl-DMT
5-Ethyl-''N'',''N''-dimethyltryptamine is a tryptamine derivative which acts as an agonist at the 5-HT1A and 5-HT1D serotonin receptors, with around 3x selectivity for 5-HT1D.
See also
* 5-Benzyloxytryptamine
* 5-Carboxamidotryptamine
* 5-Et ...
References
N,N-Dialkyltryptamines
Dimethylamino compounds
Psychedelic tryptamines
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