5-Cyclohexadecenone is a macrocyclic synthetic musk with the chemical formula C₁₆H₂₈O. It is an unsaturated

analog Analog or analogue may refer to: Computing and electronics * Analog signal, in which information is encoded in a continuous variable ** Analog device, an apparatus that operates on analog signals *** Analog electronics, circuits which use analo ...

cyclohexadecanone Cyclohexadecanone is an organic compound with the formula (CH2)15CO. It is a cyclic ketone, which is a minor component of the musk scent of the civet. Several related derivatives are also important in the fragrance industry, especially those ...

. It is also similar in chemical structure to the natural musk scents

civetone Civetone is a macrocyclic ketone and the main odorous constituent of civet oil. It is a pheromone sourced from the African civet. It has a strong musky odor that becomes pleasant at extreme dilutions. Civetone is closely related to muscone, the pr ...

and

muscone Muscone is an organic compound that is the primary contributor to the odor of musk. The chemical structure of muscone was first elucidated by Leopold Ružička. It consists of a 15-membered ring ketone with one methyl substituent in the 3-positi ...

. 5-Cyclohexadecenone has a strong musk scent with floral, amber, and civet tones. It is used as a substitute for natural musk in perfumes, cosmetics, and soaps. Trade names include Ambretone, Velvione, and TM-II. 5-Cyclohexadecenone can exist as either of two ''cis''/''trans'' isomers and the commercial product is typically a mixture of the two. It can be synthesized in a four-step sequence from cyclododecanone.

References

Macrocycles Ketones Perfume ingredients {{organic-compound-stub