4-Maleylacetoacetate (4-maleylacetoacetatic acid) is an intermediate in the metabolism of

tyrosine -Tyrosine or tyrosine (symbol Tyr or Y) or 4-hydroxyphenylalanine is one of the 20 standard amino acids that are used by cells to synthesize proteins. It is a conditionally essential amino acid with a polar side group. The word "tyrosine" is ...

. It is converted to fumarylacetoacetate by the

enzyme An enzyme () is a protein that acts as a biological catalyst by accelerating chemical reactions. The molecules upon which enzymes may act are called substrate (chemistry), substrates, and the enzyme converts the substrates into different mol ...

4-maleylacetoacetate cis-trans-isomerase In enzymology, maleylacetoacetate isomerase () is an enzyme that catalysis, catalyzes the chemical reaction :4-maleylacetoacetate \rightleftharpoons 4-fumarylacetoacetate This enzyme belongs to the family of isomerases, specifically Cis-trans is ...

. Gluthathione coenzymatically helps in conversion to fumarylacetoacetic acid.

See also