4-HO-DSBT
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4-HO-DsBT (4-hydroxy-''N,N''-di-''sec''-butyltryptamine) is a
tryptamine Tryptamine is an indolamine metabolite of the essential amino acid tryptophan. The chemical structure is defined by an indole—a fused benzene and pyrrole ring, and a 2-aminoethyl group at the second carbon (third aromatic atom, with the firs ...
derivative which acts as a
serotonin receptor 5-HT receptors, 5-hydroxytryptamine receptors, or serotonin receptors, are a group of G protein-coupled receptor and ligand-gated ion channels found in multiple tissues including the central and peripheral nervous systems. They mediate both ex ...
agonist An agonist is a chemical that activates a Receptor (biochemistry), receptor to produce a biological response. Receptors are Cell (biology), cellular proteins whose activation causes the cell to modify what it is currently doing. In contrast, an R ...
. It was first made by
Alexander Shulgin Alexander Theodore "Sasha" Shulgin (June 17, 1925 – June 2, 2014) was an American biochemist, broad researcher of synthetic psychoactive compounds, and author of works regarding these, who independently explored the organic chemistry and ph ...
and is mentioned in his book TiHKAL, but was never tested by him. However it has subsequently been tested ''in vitro'' and unlike the ''n''-butyl and isobutyl isomers which are much weaker, the ''s''-butyl derivative retains reasonable potency, with a similar 5-HT2A receptor affinity to MiPT but better selectivity over the 5-HT1A and 5-HT2B subtypes.


See also

*
4-HO-DiPT 4-HO-DiPT, also known as 4-hydroxy-''N'',''N''-diisopropyltryptamine or as iprocin, is a synthetic compound, synthetic psychedelic drug of the substituted tryptamine, tryptamine family. It is a higher homologous series, homologue of psilocin and ...
* 4-HO-DBT *
4-HO-McPeT 4-HO-McPeT (4-hydroxy-''N''-methyl-''N''-cyclopentyltryptamine) is a tryptamine derivative which has serotonergic effects. See also * 4-HO-DSBT * 4-HO-McPT * 4-HO-MPMI 4-HO-MPMI (also known as 4-Hydroxy-''N''-methyl-(α,''N''-trimethylene) ...
* 4-HO-PiPT * 5-MeO-DBT *
Dibutyltryptamine ''N'',''N''-Dibutyltryptamine (DBT) is a psychedelic drug belonging to the tryptamine family. DBT was synthesized by the chemist Alexander Shulgin and described in his book '' TiHKAL (Tryptamines i Have Known And Loved)''. Use and effects Shulg ...
*
N-t-Butyltryptamine ''N''-''t''-Butyltryptamine (NTBT) is a tryptamine derivative which has serotonergic effects. It is described by Alexander Shulgin as producing "a light-headed intoxication that is a totally pleasant buzz, but nothing more profound than that" at ...
* Robalzotan


References

N,N-Dialkyltryptamines 4-Hydroxytryptamines {{psychoactive-stub