4-DAMP (1,1-dimethyl-4-diphenylacetoxypiperidinium iodide) is a selective
muscarinic acetylcholine receptor
Muscarinic acetylcholine receptors (mAChRs) are acetylcholine receptors that form G protein-coupled receptor, G protein-coupled receptor complexes in the cell membranes of certain neurons and other Cell (biology), cells. They play several role ...
(mAChR) M3
antagonist
An antagonist is a character in a story who is presented as the main enemy or rival of the protagonist and is often depicted as a villain.M1 receptors but has preferential activity at the M3 receptor. It competitively binds to the acetylcholine binding site on mAChRs, causing right-ward shift in the dose response curves for mAChR agonists.