3-Hydroxybenzoate—CoA ligase (, ''3-hydroxybenzoyl-CoA synthetase'', ''3-hydroxybenzoate-coenzyme A ligase (AMP-forming)'', ''3-hydroxybenzoyl coenzyme A synthetase'', ''3-hydroxybenzoyl-CoA ligase'') is an
enzyme
An enzyme () is a protein that acts as a biological catalyst by accelerating chemical reactions. The molecules upon which enzymes may act are called substrate (chemistry), substrates, and the enzyme converts the substrates into different mol ...
with
systematic name
A systematic name is a name given in a systematic way to one unique group, organism, object or chemical substance, out of a specific population or collection. Systematic names are usually part of a nomenclature.
A semisystematic name or semitrivi ...
''3-hydroxybenzoate:CoA ligase (AMP-forming)''.
This enzyme
catalyses the following
chemical reaction
A chemical reaction is a process that leads to the chemistry, chemical transformation of one set of chemical substances to another. When chemical reactions occur, the atoms are rearranged and the reaction is accompanied by an Gibbs free energy, ...
: ATP + 3-hydroxybenzoate + CoA
AMP +
diphosphate
In chemistry, pyrophosphates are phosphorus oxyanions that contain two phosphorus atoms in a linkage. A number of pyrophosphate salts exist, such as disodium pyrophosphate () and tetrasodium pyrophosphate (), among others. Often pyrophosphate ...
+ 3-hydroxybenzoyl-CoA
The enzyme works equally well with
4-hydroxybenzoate
4-Hydroxybenzoic acid, also known as ''p''-hydroxybenzoic acid (PHBA), is a monohydroxybenzoic acid, a phenolic derivative of benzoic acid. It is a white crystalline solid that is slightly soluble in water and chloroform but more soluble in polar ...
.
References
External links
*
{{DEFAULTSORT:3-hydroxybenzoate-CoA ligase
EC 6.2.1