3-dehydroquinate synthase II (, ''DHQ synthase II'', ''MJ1249 (gene)'', ''aroB' (gene)'') is an
enzyme
Enzymes () are proteins that act as biological catalysts by accelerating chemical reactions. The molecules upon which enzymes may act are called substrate (chemistry), substrates, and the enzyme converts the substrates into different molecule ...
with
systematic name A systematic name is a name given in a systematic way to one unique group, organism, object or chemical substance, out of a specific population or collection. Systematic names are usually part of a nomenclature.
A semisystematic name or semitrivial ...
''2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate:NAD
+ oxidoreductase (deaminating)''.
This enzyme
catalyses the following
chemical reaction
A chemical reaction is a process that leads to the chemical transformation of one set of chemical substances to another. Classically, chemical reactions encompass changes that only involve the positions of electrons in the forming and break ...
: 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate + H
2O + NAD
+ 3-dehydroquinate + NH
3 + NADH + H
+
The enzyme was isolated from the
archaeon
Archaea ( ; singular archaeon ) is a domain of single-celled organisms. These microorganisms lack cell nuclei and are therefore prokaryotes. Archaea were initially classified as bacteria, receiving the name archaebacteria (in the Archaebact ...
''
Methanocaldococcus jannaschii
''Methanocaldococcus jannaschii'' (formerly ''Methanococcus jannaschii'') is a thermophilic methanogenic archaean in the class Methanococci. It was the first archaeon to have its complete genome sequenced. The sequencing identified many genes ...
''.
References
External links
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