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The 2000 Simpsonwood CDC conference (officially titled Scientific Review of Vaccine Safety Datalink Information) was a two-day meeting convened in June 2000 by the
Centers for Disease Control and Prevention The Centers for Disease Control and Prevention (CDC) is the national public health agency of the United States. It is a United States federal agency, under the Department of Health and Human Services, and is headquartered in Atlanta, Georgi ...
(CDC), held at the Simpsonwood Methodist retreat and conference center in Norcross, Georgia. The key event at the conference was the presentation of data from the Vaccine Safety Datalink examining the possibility of a link between the mercury compound thimerosol in vaccines and neurological problems in children who had received those vaccines. A 2005 article by
Robert F. Kennedy, Jr. Robert Francis Kennedy Jr. (born January 17, 1954) is an American environmental lawyer and author known for promoting anti-vaccine propaganda and conspiracy theories. Kennedy is a son of U.S. senator Robert F. Kennedy and a nephew of President ...
, published by ''
Rolling Stone ''Rolling Stone'' is an American monthly magazine that focuses on music, politics, and popular culture. It was founded in San Francisco, San Francisco, California, in 1967 by Jann Wenner, and the music critic Ralph J. Gleason. It was first kno ...
'' and
Salon.com ''Salon'' is an American politically progressive/liberal news and opinion website created in 1995. It publishes articles on U.S. politics, culture, and current events. Content and coverage ''Salon'' covers a variety of topics, including re ...
, focused on the Simpsonwood meeting as part of a conspiracy to withhold or falsify vaccine-safety information. However, Kennedy's article contained numerous major factual errors and, after a number of corrections, was ultimately retracted by Salon.com. Nonetheless, on the basis of Kennedy's claims, the conference gained notoriety in the
anti-vaccination movement Vaccine hesitancy is a delay in acceptance, or refusal, of vaccines despite the availability of vaccine services and supporting evidence. The term covers refusals to vaccinate, delaying vaccines, accepting vaccines but remaining uncertain abou ...
.


The conference

The conference was convened following a resolution by the Congress of the United States in 1997 requiring the
Food and Drug Administration The United States Food and Drug Administration (FDA or US FDA) is a List of United States federal agencies, federal agency of the United States Department of Health and Human Services, Department of Health and Human Services. The FDA is respon ...
(FDA) to review the thimerosal content of approved drugs and biologics. Three vaccines of primary interest were discussed: hepatitis B vaccine,
DPT vaccine The DPT vaccine or DTP vaccine is a class of combination vaccines against three infectious diseases in humans: diphtheria, pertussis (whooping cough), and tetanus. The vaccine components include diphtheria and tetanus toxoids and either kille ...
, and the
Hib vaccine The ''Haemophilus influenzae'' type B vaccine, also known as Hib vaccine, is a vaccine used to prevent ''Haemophilus influenzae'' type b (Hib) infection. In countries that include it as a routine vaccine, rates of severe Hib infections have d ...
. Attendees included experts in the fields of
autism The autism spectrum, often referred to as just autism or in the context of a professional diagnosis autism spectrum disorder (ASD) or autism spectrum condition (ASC), is a neurodevelopmental condition (or conditions) characterized by difficulti ...
, pediatrics, toxicology, epidemiology and vaccines. Also in attendance were approximately half a dozen public-health organisations and pharmaceutical companies, as well as eleven consultants to the CDC, a rapporteur, and a statistician. The meeting served as a prelude to vaccine policy meetings held by the Advisory Committee on Immunization Practices (ACIP), which sets U.S. vaccine policy for the CDC. The session was also to serve as the initial meeting of the ACIP work group on thimerosal and
immunization Immunization, or immunisation, is the process by which an individual's immune system becomes fortified against an infectious agent (known as the immunogen). When this system is exposed to molecules that are foreign to the body, called ''non-sel ...
. Presentations and supporting documents from the conference were subject to a
news embargo In journalism and public relations, a news embargo or press embargo is a request or requirement by a source that the information or news provided by that source not be published until a certain date or certain conditions have been met. They are of ...
until June 21, 2000, at which point they were published by the ACIP. Transcript: pp. 256–257 After the conference, researchers carried out a planned second phase to further analyze and clarify the study's preliminary findings. The results of this second analysis were published in 2003.


In the anti-vaccination movement

The June 20, 2005, issue of ''
Rolling Stone ''Rolling Stone'' is an American monthly magazine that focuses on music, politics, and popular culture. It was founded in San Francisco, San Francisco, California, in 1967 by Jann Wenner, and the music critic Ralph J. Gleason. It was first kno ...
'' contained an article written by
Robert F. Kennedy, Jr. Robert Francis Kennedy Jr. (born January 17, 1954) is an American environmental lawyer and author known for promoting anti-vaccine propaganda and conspiracy theories. Kennedy is a son of U.S. senator Robert F. Kennedy and a nephew of President ...
, entitled "
Deadly Immunity "Deadly Immunity" is an article written by Robert F. Kennedy, Jr. that appeared in the July 14, 2005 issue of ''Rolling Stone'' and, simultaneously, on the website ''Salon''. The article is focused on the 2000 Simpsonwood CDC conference and cla ...
". The article, which was also published on
Salon.com ''Salon'' is an American politically progressive/liberal news and opinion website created in 1995. It publishes articles on U.S. politics, culture, and current events. Content and coverage ''Salon'' covers a variety of topics, including re ...
, focused on the Simpsonwood conference, and alleged that government and private industry had colluded to "thwart the Freedom of Information Act" and "withhold" vaccine-safety findings from the public. Kennedy said that the Simpsonwood data linked thimerosal in vaccines to the rise in autism, but that the lead researcher later "reworked his data to bury the link between thimerosal and autism." However, Kennedy's article contained numerous errors, including overstating the amount of
ethylmercury Ethylmercury (sometimes ethyl mercury) is a cation composed of an organic CH3CH2- species (an ethyl group) bound to a mercury(II) centre, making it a type of organometallic cation, and giving it a chemical formula C2H5Hg+. The main source of eth ...
in vaccines, wrongly claiming that a researcher held a patent on one of the discussed vaccines, and erroneously claiming that the
rotavirus vaccine Rotavirus vaccine is a vaccine used to protect against rotavirus infections, which are the leading cause of severe diarrhea among young children. The vaccines prevent 15–34% of severe diarrhea in the developing world and 37–96% of se ...
contained thimerosal. Salon.com later said that the errors in the article "went far in undermining Kennedy’s exposé", and corrected it on five occasions. The publisher later retracted it in January 2011, stating that criticisms of the article and flaws in the science connecting autism and vaccines undermined its value. By the time the final study results discussed at Simpsonwood were published in 2003, the lead researcher, Thomas Verstraeten, had gone to work for
GlaxoSmithKline GSK plc, formerly GlaxoSmithKline plc, is a British multinational pharmaceutical and biotechnology company with global headquarters in London, England. Established in 2000 by a merger of Glaxo Wellcome and SmithKline Beecham. GSK is the ten ...
. Kennedy contended that the delay in publication gave Verstraeten sufficient time to fix the data around the CDC's alleged objective of obscuring a link between thimerosal and autism. Verstraeten denied the allegations, and published an account of the matter in the journal ''
Pediatrics Pediatrics ( also spelled ''paediatrics'' or ''pædiatrics'') is the branch of medicine that involves the medical care of infants, children, adolescents, and young adults. In the United Kingdom, paediatrics covers many of their youth until th ...
''. In September 2007, the U.S. Senate Committee on Health, Education, Labor and Pensions rejected allegations of impropriety against Verstraeten and the CDC. Addressing Kennedy's statements, the Committee found that: "Instead of hiding the impsonwooddata or restricting access to it, CDC distributed it, often to individuals who had never seen it before, and solicited outside opinion regarding how to interpret it. The transcript of these discussions was made available to the public."


See also

*
Thiomersal and vaccines Thiomersal (or thimerosal) is a mercury compound which is used as a preservative in some vaccines. Anti-vaccination activists promoting the incorrect claim that vaccination causes autism have asserted that the mercury in thiomersal is the cause. ...


Notes


References

* * Hosted by SafeMinds, {{DEFAULTSORT:Simpsonwood Cdc Conference Simpsonwood CDC conference, 2000 Simpsonwood CDC conference, 2000 Centers for Disease Control and Prevention Conspiracy theories in the United States 2000 conferences Thiomersal and vaccines 2000 in Georgia (U.S. state)