2-Picolylamine is an

organic compound Some chemical authorities define an organic compound as a chemical compound that contains a carbon–hydrogen or carbon–carbon bond; others consider an organic compound to be any chemical compound that contains carbon. For example, carbon-co ...

with the formula H₂NCH₂C₅H₄N. A colorless liquid, it is a common

bidentate ligand In coordination chemistry, a ligand is an ion or molecule with a functional group that binds to a central metal atom to form a coordination complex. The bonding with the metal generally involves formal donation of one or more of the ligand's ...

and a precursor to more complex multidentate ligands such as tris(2-pyridylmethyl)amine. It is usually prepared by hydrogenation of 2-cyano

pyridine Pyridine is a basic (chemistry), basic heterocyclic compound, heterocyclic organic compound with the chemical formula . It is structurally related to benzene, with one methine group replaced by a nitrogen atom . It is a highly flammable, weak ...

. One such complex is Baratta's catalyst RuCl₂(PPh₃)₂(ampy) (ampy = 2-picolylamine) for

transfer hydrogenation In chemistry, transfer hydrogenation is a chemical reaction involving the addition of hydrogen to a compound from a source other than molecular . It is applied in laboratory and industrial organic synthesis to saturate organic compounds and re ...

. Salts of the complex e(pyCH₂NH₂)₃sup>2+ exhibit

spin crossover Spin crossover (SCO) is a phenomenon that occurs in some metal Coordination complex, complexes wherein the Spin states (d electrons), spin state of the complex changes due to an external stimulus. The stimuli can include temperature, pressure or ...

behavior, whereby the complex switches from high to low spin configurations, depending on the temperature.

Safety

The oral in

quail Quail is a collective name for several genera of mid-sized birds generally placed in the order Galliformes. The collective noun for a group of quail is a flock, covey, or bevy. Old World quail are placed in the family Phasianidae, and New ...

is low, being 750 mg/kg.

References

{{DEFAULTSORT:Picolylamine, 2- 2-Pyridyl compounds Amines