2-''C''-Methyl--erythritol 4-phosphate (MEP) is an intermediate on the
MEP pathway
The non-mevalonate pathway—also appearing as the mevalonate-independent pathway and the 2-''C''-methyl-D-erythritol 4-phosphate/1-deoxy-D-xylulose 5-phosphate (MEP/DOXP) pathway—is an alternative metabolic pathway for the biosynthesis of the i ...
(non-mevalonate pathway) of isoprenoid precursor biosynthesis.
It is the first committed metabolite on that pathway on the route to
IPP IPP may refer to:
Organisations
* Independent Power Producer, electric power generator
* India Pride Project, recovering stolen Indian artefacts
* Istituto per la Protezione delle Piante (Institute of Plant Protection), Italy
* Max-Planck-Insti ...
and
DMAPP
Dimethylallyl pyrophosphate (DMAPP; or alternatively, dimethylallyl diphosphate (DMADP); also isoprenyl pyrophosphate) is an isoprenoid precursor. It is a product of both the mevalonate pathway and the MEP pathway of isoprenoid precursor biosynth ...
.
See also
*
DXP reductoisomerase
DXP reductoisomerase (1-deoxy-D-xylulose 5-phosphate reductoisomerase or DXR) is an enzyme that interconverts 1-deoxy-D-xylulose 5-phosphate (DXP) and 2-C-methyl-D-erythritol 4-phosphate (MEP).
Image:DOXP.png, 1-Deoxy-D-xylulose 5-phosphate
...
*
MEP pathway
The non-mevalonate pathway—also appearing as the mevalonate-independent pathway and the 2-''C''-methyl-D-erythritol 4-phosphate/1-deoxy-D-xylulose 5-phosphate (MEP/DOXP) pathway—is an alternative metabolic pathway for the biosynthesis of the i ...
(formerly known as the non-mevalonate pathway)
*
Fosmidomycin
Fosmidomycin is an antibiotic that was originally isolated from culture broths of bacteria of the genus ''Streptomyces''. It specifically inhibits DXP reductoisomerase, a key enzyme in the non-mevalonate pathway of isoprenoid biosynthesis. It is ...
References
External links
*
Organophosphates
Monosaccharide derivatives
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