Oxofluoxymesterone (developmental code name U-6596), or ketofluoxymesterone, is an
androgen
An androgen (from Greek ''andr-'', the stem of the word meaning ) is any natural or synthetic steroid hormone that regulates the development and maintenance of male characteristics in vertebrates by binding to androgen receptors. This includes ...
and
anabolic steroid
Anabolic steroids, also known as anabolic-androgenic steroids (AAS), are a class of drugs that are structurally related to testosterone, the main male sex hormone, and produce effects by binding to the androgen receptor (AR). Anabolism, Anaboli ...
(AAS) which was never marketed.
It was assessed in the treatment of
breast cancer
Breast cancer is a cancer that develops from breast tissue. Signs of breast cancer may include a Breast lump, lump in the breast, a change in breast shape, dimpling of the skin, Milk-rejection sign, milk rejection, fluid coming from the nipp ...
in women in the 1970s and showed effectiveness similar to that of other AAS.
The drug is the 11-
dehydrogenated analogue and a
metabolite
In biochemistry, a metabolite is an intermediate or end product of metabolism.
The term is usually used for small molecules. Metabolites have various functions, including fuel, structure, signaling, stimulatory and inhibitory effects on enzymes, c ...
of
fluoxymesterone
Fluoxymesterone, sold under the brand names Halotestin and Ultandren among others, is an androgen and anabolic steroid (AAS) medication which is used in the treatment of hypogonadism, low testosterone levels in men, delayed puberty in boys, breas ...
.
See also
*
Dihydrofluoxymesterone
References
Abandoned drugs
Tertiary alcohols
Anabolic–androgenic steroids
Androstanes
Diketones
Hepatotoxins
Hormonal antineoplastic drugs
Human drug metabolites
Organofluorides
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