11-Hydroxycannabinol (11-OH-CBN) is the main active metabolite of
cannabinol
Cannabinol (CBN) is a mildly psychoactive phytocannabinoid that acts as a low affinity partial agonist at both CB1 and CB2 receptors. This activity at CB1 and CB2 receptors constitutes interaction of CBN with the endocannabinoid system (ECS) ...
(CBN), one of the active components of
cannabis
''Cannabis'' () is a genus of flowering plants in the family Cannabaceae that is widely accepted as being indigenous to and originating from the continent of Asia. However, the number of species is disputed, with as many as three species be ...
, and has also been isolated from cannabis itself.
It is more potent than CBN itself, acting as an agonist of CB
1 with around the same potency as
THC, but is a weak antagonist at CB
2.
See also
*
11-Hydroxyhexahydrocannabinol
*
11-Hydroxy-THC
*
11-Hydroxy-Delta-8-THC
*
Cannabinodiol
References
Cannabinoids
Benzochromenes
Diols
Hydroxyarenes
Human drug metabolites
{{cannabinoid-stub