α-Santalol (''alpha''-santalol) is an

organic compound Some chemical authorities define an organic compound as a chemical compound that contains a carbon–hydrogen or carbon–carbon bond; others consider an organic compound to be any chemical compound that contains carbon. For example, carbon-co ...

that is classified as a

sesquiterpene Sesquiterpenes are a class of terpenes that consist of three isoprene units and often have the molecular formula C15H24. Like monoterpenes, sesquiterpenes may be cyclic or contain rings, including many combinations. Biochemical modifications s ...

. It comprises about 55% of the oil of

sandalwood Sandalwood is a class of woods from trees in the genus ''Santalum''. The woods are heavy, yellow, and fine-grained, and, unlike many other aromatic woods, they retain their fragrance for decades. Sandalwood oil is extracted from the woods. Sanda ...

, another less abundant component being

β-santalol β-Santalol is an organic compound that is classified as a sesquiterpene. It comprises about 20% of the oil of sandalwood, the major component being α-santalol. In 2002, about 60 tons of sandalwood oil were produced by steam distillation of the ...

. As of 2002, about 60 tons of

sandalwood oil Sandalwood oil is an essential oil obtained from the steam distillation of chips and billets cut from the heartwood of various species of sandalwood trees, mainly ''Santalum album'' (Indian sandalwood) and ''Santalum spicatum'' (Australian sanda ...

are produced annually by

steam distillation Steam distillation is a separation process that consists of distilling water together with other volatile and non-volatile components. The steam from the boiling water carries the vapor of the volatiles to a condenser; both are cooled and retu ...

of the heartwood of ''

Santalum album ''Santalum album'' is a small tropical tree, and the traditional source of sandalwood oil. It is native to Indonesia (Java and the Lesser Sunda Islands), the Philippines, and Western Australia. It is commonly known as the true sandalwood, white ...

''. It is a valued component for perfumes. Because of concerns about the sustainability of sandalwood tree cultivation, scientists have developed routes to α-santalol and

via fermentation, including using ''

Rhodobacter sphaeroides ''Rhodobacter sphaeroides'' is a kind of purple bacterium; a group of bacteria that can obtain energy through photosynthesis. Its best growth conditions are anaerobic phototrophy ( photoheterotrophic and photoautotrophic) and aerobic chemoh ...

''. BASF launched its version under their Isobionics brand in July 2020. The oil content varies greatly within the different sandalwood species. This level is typically highest in ''S. album'', '' S. paniculatum'' and '' S. yasi''. The scent profile also changes considerably between the different species' oils.

References

Perfume ingredients Primary alcohols Sesquiterpenes Cyclopropanes {{alcohol-stub ru:Санталол