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Wolf-dog Hybrid
A wolfdog is a canine produced by the mating of a domestic dog (''Canis familiaris'') with a gray wolf (''Canis lupus''), eastern wolf (''Canis lycaon''), red wolf (''Canis rufus''), or Ethiopian wolf (''Canis simensis'') to produce a hybrid. Admixture There are a range of experts who believe that they can tell the difference between a wolf, a dog, and a wolfdog, but they have been proven to be incorrect when providing their evidence before courts of law. Admixture between domestic dogs and other subspecies of gray wolves are the most common wolfdogs since dogs and gray wolves are considered the same species, are genetically very close and have shared vast portions of their ranges for millennia. Such admixture in the wild have been detected in many populations scattered throughout Europe and North America, usually occurring in areas where wolf populations have declined from human impacts and persecutions. At the same time, wolfdogs are also often bred in captivity for v ...
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Arctic Wolf
The Arctic wolf (''Canis lupus arctos''), also known as the white wolf, polar wolf, and the Arctic grey wolf, is a Subspecies of Canis lupus, subspecies of grey wolf native to the High Arctic tundra of Canada's Queen Elizabeth Islands, from Melville Island (Northwest Territories and Nunavut), Melville Island to Ellesmere Island. Unlike some populations that move between tundra and forest regions, Arctic wolves spend their entire lives north of the northern treeline. Their distribution to south is limited to the northern fringes of the Middle Arctic tundra on the southern half of Prince of Wales Island (Nunavut), Prince of Wales and Somerset Island (Nunavut), Somerset Islands. It is a medium-sized subspecies, distinguished from the northwestern wolf by its smaller size, whiter colouration, narrower Neurocranium, braincase,Goldman, E. A. (1964). Classification of wolves. In ''The Wolves of North America'' Part 2. Young, S. P. & Goldman, E. A. (Eds.) New York: Dover Publs. p. 430. ...
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Fédération Cynologique Internationale
The (; FCI; ) is the largest international federation of national kennel clubs and purebred registries. The FCI is based in Thuin, Belgium and has 98 members and contract partners (one from each country). History The FCI was founded in 1911 under the auspices of the kennel clubs of Austria, Belgium, France, Germany and the Netherlands. Its objective was to bring global uniformity to the breeding, exhibiting and judging of pure-bred dogs. It was disbanded in World War I and recreated in 1921 by Belgium and France. Since its foundation the FCI's membership has grown to include kennel clubs from the majority of countries worldwide, with members in Europe as well as Africa, the Americas, Asia and Oceania. Function The purpose of the FCI is to make sure that the pedigrees and judges are mutually recognised by all the FCI member countries. In contrast to national kennel clubs, the FCI is not a registry and does not issue pedigrees to individual dogs, with the issue of pedigrees and ...
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Apennines
The Apennines or Apennine Mountains ( ; or Ἀπέννινον ὄρος; or – a singular with plural meaning; )Latin ''Apenninus'' (Greek or ) has the form of an adjective, which would be segmented ''Apenn-inus'', often used with nouns such as ("mountain") or Greek (), but ''Apenninus'' is just as often used alone as a noun. The ancient Greeks and Romans typically but not always used "mountain" in the singular to mean one or a range; thus, "the Apennine mountain" refers to the entire chain and is translated "the Apennine mountains". The ending can vary also by gender depending on the noun modified. The Italian singular refers to one of the constituent chains rather than to a single mountain, and the Italian plural refers to multiple chains rather than to multiple mountains. are a mountain range consisting of parallel smaller chains extending the length of peninsular Italy. In the northwest they join the Ligurian Alps at Altare. In the southwest they end at Reggio di ...
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Italy
Italy, officially the Italian Republic, is a country in Southern Europe, Southern and Western Europe, Western Europe. It consists of Italian Peninsula, a peninsula that extends into the Mediterranean Sea, with the Alps on its northern land border, as well as List of islands of Italy, nearly 800 islands, notably Sicily and Sardinia. Italy shares land borders with France to the west; Switzerland and Austria to the north; Slovenia to the east; and the two enclaves of Vatican City and San Marino. It is the List of European countries by area, tenth-largest country in Europe by area, covering , and the third-most populous member state of the European Union, with nearly 59 million inhabitants. Italy's capital and List of cities in Italy, largest city is Rome; other major cities include Milan, Naples, Turin, Palermo, Bologna, Florence, Genoa, and Venice. The history of Italy goes back to numerous List of ancient peoples of Italy, Italic peoples—notably including the ancient Romans, ...
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Beta-defensin 3
Beta-defensin 3 is a protein that in humans is encoded by the ''DEFB3'' gene In biology, the word gene has two meanings. The Mendelian gene is a basic unit of heredity. The molecular gene is a sequence of nucleotides in DNA that is transcribed to produce a functional RNA. There are two types of molecular genes: protei .... HBD-3 was first isolated from human lesional psoriatic scales. RT-PCR showed HBD-3 to be expressed highly in skin, trachea, tongue and tonsils, with lower levels found salivary glands, uterus, kidney, bone marrow, thymus, colon, stomach, adenoid, pharynx, and larynx. References {{reflist Peripheral membrane proteins Defensins ...
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Protein
Proteins are large biomolecules and macromolecules that comprise one or more long chains of amino acid residue (biochemistry), residues. Proteins perform a vast array of functions within organisms, including Enzyme catalysis, catalysing metabolic reactions, DNA replication, Cell signaling, responding to stimuli, providing Cytoskeleton, structure to cells and Fibrous protein, organisms, and Intracellular transport, transporting molecules from one location to another. Proteins differ from one another primarily in their sequence of amino acids, which is dictated by the Nucleic acid sequence, nucleotide sequence of their genes, and which usually results in protein folding into a specific Protein structure, 3D structure that determines its activity. A linear chain of amino acid residues is called a polypeptide. A protein contains at least one long polypeptide. Short polypeptides, containing less than 20–30 residues, are rarely considered to be proteins and are commonly called pep ...
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Mutation
In biology, a mutation is an alteration in the nucleic acid sequence of the genome of an organism, virus, or extrachromosomal DNA. Viral genomes contain either DNA or RNA. Mutations result from errors during DNA or viral replication, mitosis, or meiosis or other types of damage to DNA (such as pyrimidine dimers caused by exposure to ultraviolet radiation), which then may undergo error-prone repair (especially microhomology-mediated end joining), cause an error during other forms of repair, or cause an error during replication ( translesion synthesis). Mutations may also result from substitution, insertion or deletion of segments of DNA due to mobile genetic elements. Mutations may or may not produce detectable changes in the observable characteristics ( phenotype) of an organism. Mutations play a part in both normal and abnormal biological processes including: evolution, cancer, and the development of the immune system, including junctional diversity. Mutati ...
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Adolph Murie
Adolph Murie (September 6, 1899 – August 16, 1974), the first scientist to study wolves in their natural habitat, was a naturalist, author, and wildlife biologist who pioneered field research on wolves, bears, and other mammals and birds in Arctic and sub-Arctic Alaska. He was also instrumental in protecting wolves from eradication and in preserving the biological integrity of the Denali National Park and the Arctic National Wildlife Refuge. In 1989 Professor John A. Murray of the English Department at the University of Alaska, Fairbanks received an NEH grant to inventory the extensive Adolph Murie written and slide archives at Rasmusson Library in the Arctic and Polar Collection. He wrote a forty-page report and biographical narrative of Adolph Murie, which remains unpublished but which is in his papers. Early life Adolf Winstrom was born on September 6, 1899, in Moorhead, Minnesota, the child of Ed and Marie Winstrom. In 1922, prior to completing college, Adolph Murie joined ...
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Teotihuacan
Teotihuacan (; Spanish language, Spanish: ''Teotihuacán'', ; ) is an ancient Mesoamerican city located in a sub-valley of the Valley of Mexico, which is located in the State of Mexico, northeast of modern-day Mexico City. Teotihuacan is known today as the site of many of the most architecturally significant Mesoamerican pyramids built in the pre-Columbian Americas, namely the Pyramid of the Sun and the Pyramid of the Moon. Although close to Mexico City, Teotihuacan was not a Mexica (i.e. Aztec) city, and it predates the Aztec Empire by many centuries. At its zenith, perhaps in the first half of the first millennium (1 CE to 500 CE), Teotihuacan was the largest city in the Americas, with a population of at least 25,000, but has been estimated at 125,000 or more, making it at least the sixth-largest city in the world during its epoch. The city covered   and 80 to 90 percent of the total population of the valley resided in Teotihuacan. Apart from the pyramids, Teotihu ...
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Sarloos Wolfdog
The Saarloos Wolfdog (, ) is a wolfdog Dog breed, breed originating from the Netherlands by the crossing of a German Shepherd with a Eurasian wolf, Siberian grey wolf in 1935. The offspring were then further crossed with German Shepherds. History Leendert Saarloos (1884–1969) was a Dutch Zoology, zoologist and dog breeder who believed that the German Shepherd had become too domesticated and wanted to breed back the more natural properties in order to derive a better working dog. In 1935, he bred a male German Shepherd (, ) to a female Eurasian grey wolf (''Canis lupus lupus'') from Siberia. He then bred the offspring back with German Shepherds to derive a dog with one quarter wolf blood. The result was a dog that was not useful as a working dog but as companion that is close to nature. The Dutch Kennel Club recognized the breed in 1975 as "Saarlooswolfdog", after its creator. In 1981, the breed was recognized by the Fédération Cynologique Internationale (FCI). Genetic e ...
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Gene Flow
In population genetics, gene flow (also known as migration and allele flow) is the transfer of genetic variation, genetic material from one population to another. If the rate of gene flow is high enough, then two populations will have equivalent allele frequencies and therefore can be considered a single effective population. It has been shown that it takes only "one migrant per generation" to prevent populations from diverging due to Genetic drift, drift. Populations can diverge due to Natural selection, selection even when they are exchanging alleles, if the selection pressure is strong enough. Gene flow is an important mechanism for transferring genetic diversity among populations. Migrants change the distribution of genetic diversity among populations, by modifying allele frequencies (the proportion of members carrying a particular variant of a gene). High rates of gene flow can reduce the genetic differentiation between the two groups, increasing homogeneity. Gene flow has b ...
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