Widow Maker (medicine)
The left anterior descending artery (LAD, or anterior descending branch), also called anterior interventricular artery (IVA, or anterior interventricular branch of left coronary artery) is a branch of the left coronary artery. It supplies the anterior portion of the Left Ventricle, left ventricle. It provides about half of the arterial supply to the left ventricle and is thus considered the most important vessel supplying the left ventricle. Vascular occlusion, Blockage of this artery is often called the ''widow-maker infarction'' due to a high risk of death. Structure Course It first passes at posterior to the pulmonary artery, then passes anteriorward between that pulmonary artery and the Atrium (heart), left atrium to reach the anterior interventricular sulcus, along which it descends to the notch of cardiac apex. In 78% of cases, it reaches the apex of the heart. Although rare, multiple anomalous courses of the LAD have been described. These include the origin of the artery ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Left Coronary Artery
The left coronary artery (LCA, also known as the left main coronary artery, or left main stem coronary artery) is a coronary artery that arises from the aorta above the left cusp of the aortic valve, and supplies blood to the left side of the heart muscle. The left coronary artery typically runs for 10–25 mm, then bifurcates into the left anterior descending artery, and the left circumflex artery. The part that is between the aorta and the bifurcation only is known as the left main artery (LM), while the term "LCA" might refer to just the left main, or to the left main and all its eventual branches. Structure Variation Sometimes, an additional artery arises at the bifurcation of the left main artery, forming a trifurcation; this extra artery is called the ''ramus'' or ''intermediate artery''. A "first septal branch" is sometimes described. Additional images File:Coronary arteries 1.jpg, Left coronary artery File:Cardiac vessels.png, Cardiac vessels File:Gray50 ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Aortic Sinus
An aortic sinus, also known as a sinus of Valsalva, is one of the anatomic dilations of the ascending aorta, which occurs just above the aortic valve. These widenings are between the wall of the aorta and each of the three cusps of the aortic valve. The aortic sinuses cause eddies which prevent the valve cusps from touching the internal surface of the aorta and obstructing the openings of the coronary arteries. Structure There are generally three aortic sinuses, one anterior and two posterior sinuses. These give rise to coronary arteries: * The left aortic or left posterior aortic sinus gives rise to the left coronary artery; * The right aortic or anterior aortic sinus gives rise to the right coronary artery; * The posterior aortic or right posterior aortic sinus usually gives rise to no vessels. It is often known as the ''non-coronary'' sinus. The aortic sinuses are typically more prominent than the pulmonary sinuses. Clinical significance If the coronary arteries aris ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Kevin Smith
Kevin Patrick Smith (born August 2, 1970) is an American film director, producer, writer, and actor. He came to prominence with the low-budget buddy comedy film ''Clerks (film), Clerks'' (1994), which he wrote, directed, co-produced, and acted in as the character Silent Bob of stoner duo Jay and Silent Bob. These characters also appeared in Smith's later films ''Mallrats'' (1995), ''Chasing Amy'' (1997), ''Dogma (film), Dogma'' (1999), ''Jay and Silent Bob Strike Back'' (2001), ''Clerks II'' (2006), ''Jay and Silent Bob Reboot'' (2019), and ''Clerks III'' (2022) which are set primarily in his home state of New Jersey. While not strictly sequential, the films have crossover plot elements, character references, and a shared canon (fiction), canon known as the "View Askewniverse", named after Smith's production company View Askew Productions, which he co-founded with Scott Mosier. Other non-"View Askewniverse" film written and directed by Smith include the comedy-drama ''Jersey Girl ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Tim Russert
Timothy John Russert (May 7, 1950 – June 13, 2008) was an American television journalist and lawyer who appeared for more than 16 years as the longest-serving moderator of NBC's '' Meet the Press''. He was a senior vice president at NBC News and Washington bureau chief, and also hosted an eponymous CNBC/MSNBC weekend interview program. He was a frequent correspondent and guest on NBC's '' The Today Show'' and '' Hardball''. Russert covered several presidential elections, and he presented the NBC News/''Wall Street Journal'' survey on the ''NBC Nightly News'' during the 2008 U.S. presidential election. ''Time'' magazine included Russert in its list of the 100 most influential people in the world in 2008. Russert was posthumously revealed as a 30-year source for syndicated columnist Robert Novak. Early life Russert was born in Buffalo, New York, the son of Elizabeth "Betty" (née Seeley; January 9, 1929 – August 14, 2005), a homemaker, and Timothy Joseph "Big Russ" Russert ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Angioplasty
Angioplasty, also known as balloon angioplasty and percutaneous transluminal angioplasty, is a minimally invasive procedure, minimally invasive endovascular surgery, endovascular Medical procedure, procedure used to widen narrowed or obstructed arteries or veins, typically to treat arterial atherosclerosis. A deflated balloon attached to a catheter (a balloon catheter) is passed over a guide-wire into the stenosis, narrowed blood vessel, vessel and then inflated to a fixed size. The balloon forces expansion of the blood vessel and the surrounding muscular wall, allowing an improved blood flow. A stent may be inserted at the time of ballooning to ensure the vessel remains open, and the balloon is then deflated and withdrawn. Angioplasty has come to include all manner of Blood vessel, vascular interventions that are typically performed percutaneously. Uses and indications Coronary angioplasty A coronary angioplasty is a therapeutic procedure to treat the stenotic (narrow ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Coronary Artery Bypass Surgery
Coronary artery bypass surgery, also known as coronary artery bypass graft (CABG, pronounced "cabbage"), is a surgical procedure to treat coronary artery disease (CAD), the buildup of plaques in the arteries of the heart. It can relieve chest pain caused by CAD, slow the progression of CAD, and increase life expectancy. It aims to bypass narrowings in heart arteries by using arteries or veins harvested from other parts of the body, thus restoring adequate blood supply to the previously ischemic (deprived of blood) heart. There are two main approaches. The first uses a cardiopulmonary bypass machine, a machine which takes over the functions of the heart and lungs during surgery by circulating blood and oxygen. With the heart in cardioplegic arrest, harvested arteries and veins are used to connect across problematic regions—a construction known as surgical anastomosis. In the second approach, called the off-pump coronary artery bypass (OPCAB), these anastomoses are cons ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Platelets
Platelets or thrombocytes () are a part of blood whose function (along with the coagulation factors) is to react to bleeding from blood vessel injury by clumping to form a blood clot. Platelets have no cell nucleus; they are fragments of cytoplasm from megakaryocytes which reside in bone marrow or lung tissue, and then enter the circulation. Platelets are found only in mammals, whereas in other vertebrates (e.g. birds, amphibians), thrombocytes circulate as intact mononuclear cells. One major function of platelets is to contribute to hemostasis: the process of stopping bleeding at the site where the lining of vessels (endothelium) has been interrupted. Platelets gather at the site and, unless the interruption is physically too large, they plug the hole. First, platelets attach to substances outside the interrupted endothelium: ''adhesion''. Second, they change shape, turn on receptors and secrete chemical messengers: ''activation''. Third, they connect to each other throu ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Myocardial Infarction
A myocardial infarction (MI), commonly known as a heart attack, occurs when Ischemia, blood flow decreases or stops in one of the coronary arteries of the heart, causing infarction (tissue death) to the heart muscle. The most common symptom is retrosternal Angina, chest pain or discomfort that classically radiates to the left shoulder, arm, or jaw. The pain may occasionally feel like heartburn. This is the dangerous type of acute coronary syndrome. Other symptoms may include shortness of breath, nausea, presyncope, feeling faint, a diaphoresis, cold sweat, Fatigue, feeling tired, and decreased level of consciousness. About 30% of people have atypical symptoms. Women more often present without chest pain and instead have neck pain, arm pain or feel tired. Among those over 75 years old, about 5% have had an MI with little or no history of symptoms. An MI may cause heart failure, an Cardiac arrhythmia, irregular heartbeat, cardiogenic shock or cardiac arrest. Most MIs occur d ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Angiography
Angiography or arteriography is a medical imaging technique used to visualize the inside, or lumen, of blood vessels and organs of the body, with particular interest in the arteries, veins, and the heart chambers. Modern angiography is performed by injecting a radio-opaque contrast agent into the blood vessel and imaging using X-ray based techniques such as fluoroscopy. With time-of-flight (TOF) magnetic resonance it is no longer necessary to use a contrast. The word itself comes from the Greek words ἀνγεῖον ''angeion'' 'vessel' and γράφειν ''graphein'' 'to write, record'. The film or image of the blood vessels is called an ''angiograph'', or more commonly an ''angiogram''. Though the word can describe both an arteriogram and a venogram, in everyday usage the terms angiogram and arteriogram are often used synonymously, whereas the term venogram is used more precisely. The term angiography has been applied to radionuclide angiography and newer vascular ima ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Papillary Muscle
The papillary muscles are muscles located in the ventricles of the heart. They attach to the cusps of the atrioventricular valves (also known as the mitral and tricuspid valves) via the chordae tendineae and contract to prevent inversion or prolapse of these valves on systole (or ventricular contraction). Structure There are five total papillary muscles in the heart; three in the right ventricle and two in the left ventricle. The anterior, posterior, and septal papillary muscles of the right ventricle each attach via chordae tendineae to the tricuspid valve. The anterolateral and posteromedial papillary muscles of the left ventricle attach via chordae tendineae to the mitral valve. Blood supply to the left ventricle The mitral valve papillary muscles in the left ventricle are called the anterolateral and posteromedial muscles. * Anterolateral muscle blood supply: left anterior descending artery - diagonal branch (LAD) and left circumflex artery - obtuse marginal bra ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Apex Of The Heart
The heart is a muscular organ found in humans and other animals. This organ pumps blood through the blood vessels. The heart and blood vessels together make the circulatory system. The pumped blood carries oxygen and nutrients to the tissue, while carrying metabolic waste such as carbon dioxide to the lungs. In humans, the heart is approximately the size of a closed fist and is located between the lungs, in the middle compartment of the chest, called the mediastinum. In humans, the heart is divided into four chambers: upper left and right atria and lower left and right ventricles. Commonly, the right atrium and ventricle are referred together as the right heart and their left counterparts as the left heart. In a healthy heart, blood flows one way through the heart due to heart valves, which prevent backflow. The heart is enclosed in a protective sac, the pericardium, which also contains a small amount of fluid. The wall of the heart is made up of three layers: epica ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |