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Urine Flow Rate
Urine flow rate or urinary flow rate is the volumetric flow rate of urine during urination. It is a measure of the quantity of urine excreted in a specified period of time (per second or per minute). It is measured with uroflowmetry, a type of flow measurement. The letters "V" (for volume) and "Q" (a conventional symbol for flow rate) are both used as a symbol for urine flow rate. The V often has a dot (overdot), that is, V̇ ("V-dot"). Qmax indicates the maximum flow rate. Qmax is used as an indicator for the diagnosis of enlarged prostate. A lower Qmax may indicate that the enlarged prostate puts pressure on the urethra, partially occluding it. Uroflowmetry is performed by urinating into a special urinal, toilet, or disposable device that has a measuring device built in. The average rate changes with age. Clinical usage Changes in the urine flow rate can be indicative of kidney, prostate or other renal disorders. Similarly, by measuring urine flow rate, it is possible to calcu ...
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Urethra
The urethra (: urethras or urethrae) is the tube that connects the urinary bladder to the urinary meatus, through which Placentalia, placental mammals Urination, urinate and Ejaculation, ejaculate. The external urethral sphincter is a striated muscle that allows voluntary control over urination. The Internal urethral sphincter, internal sphincter, formed by the involuntary smooth muscles lining the bladder neck and urethra, receives its nerve supply by the Sympathetic nervous system, sympathetic division of the autonomic nervous system. The internal sphincter is present both in males and females. Structure The urethra is a fibrous and muscular tube which connects the urinary bladder to the external urethral meatus. Its length differs between the sexes, because it passes through the penis in males. Male In the human male, the urethra is on average long and opens at the end of the external urethral meatus. The urethra is divided into four parts in men, named after the lo ...
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Renal Physiology
Renal physiology (Latin language, Latin ''renes'', "kidneys") is the study of the physiology of the kidney. This encompasses all functions of the kidney, including maintenance of acid-base balance; regulation of fluid balance; regulation of sodium, potassium, and other electrolytes; clearance (medicine), clearance of toxins; absorption of glucose, amino acids, and other small molecules; regulation of blood pressure; production of various hormones, such as erythropoietin; and activation of vitamin D. Much of renal physiology is studied at the level of the nephron, the smallest functional unit of the kidney. Each nephron begins with a #Filtration, filtration component that filters the blood entering the kidney. This filtrate then flows along the length of the nephron, which is a tubular structure lined by a single layer of specialized cell (biology), cells and surrounded by capillary, capillaries. The major functions of these lining cells are the reabsorption of water and small mol ...
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Urodynamics
Urodynamic testing or urodynamics is a study that assesses how the urinary bladder, bladder and urethra are performing their job of storing and releasing urine. Urodynamic tests can help explain symptoms such as: * Urinary incontinence, incontinence * frequent urination * sudden, strong urges to urinate but nothing comes out * problems starting a urine stream * painful urination * problems emptying the bladder completely (Vesical tenesmus, Vesical tenesmus, detrusor failure) * recurrent urinary tract infections Urodynamic tests are usually performed in urology, gynecology, OB/GYN, internal medicine, and primary care offices. Urodynamics will provide the physician with the information necessary to diagnose the cause and nature of a patient's incontinence, thus giving the best treatment options available. Urodynamics is typically conducted by urologists or urogynecologists. Purpose of testing The tests are most often arranged for men with enlarged prostate glands, and for women ...
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Meta-analysis
Meta-analysis is a method of synthesis of quantitative data from multiple independent studies addressing a common research question. An important part of this method involves computing a combined effect size across all of the studies. As such, this statistical approach involves extracting effect sizes and variance measures from various studies. By combining these effect sizes the statistical power is improved and can resolve uncertainties or discrepancies found in individual studies. Meta-analyses are integral in supporting research grant proposals, shaping treatment guidelines, and influencing health policies. They are also pivotal in summarizing existing research to guide future studies, thereby cementing their role as a fundamental methodology in metascience. Meta-analyses are often, but not always, important components of a systematic review. History The term "meta-analysis" was coined in 1976 by the statistician Gene V. Glass, Gene Glass, who stated ''"Meta-analysis refers t ...
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Benign Prostate Hyperplasia
Benign prostatic hyperplasia (BPH), also called prostate enlargement, is a noncancerous increase in size of the prostate gland. Symptoms may include frequent urination, trouble starting to urinate, weak stream, urinary retention, inability to urinate, or urinary incontinence, loss of bladder control. Complications can include urinary tract infections, bladder stones, and chronic kidney problems. The cause is unclear. Risk factors include a family history, obesity, type 2 diabetes, not enough exercise, and erectile dysfunction. Medications like pseudoephedrine, anticholinergics, and calcium channel blockers may worsen symptoms. The underlying mechanism involves the prostate pressing on the urethra thereby making it difficult to pass urine out of the bladder. Diagnosis is typically based on symptoms and Physical examination, examination after ruling out other possible causes. Treatment options include lifestyle changes, medications, a number of procedures, and surgery. In th ...
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Ageing
Ageing (or aging in American English) is the process of becoming older until death. The term refers mainly to humans, many other animals, and fungi; whereas for example, bacteria, perennial plants and some simple animals are potentially biologically immortal. In a broader sense, ageing can refer to single cells within an organism which have ceased dividing, or to the population of a species. In humans, ageing represents the accumulation of changes in a human being over time and can encompass physical, psychological, and social changes. Reaction time, for example, may slow with age, while memories and general knowledge typically increase. Of the roughly 150,000 people who die each day across the globe, about two-thirds die from age-related causes. Current ageing theories are assigned to the damage concept, whereby the accumulation of damage (such as DNA oxidation) may cause biological systems to fail, or to the programmed ageing concept, whereby the internal processes (e ...
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Benign Prostatic Hyperplasia
Benign prostatic hyperplasia (BPH), also called prostate enlargement, is a noncancerous increase in size of the prostate gland. Symptoms may include frequent urination, trouble starting to urinate, weak stream, urinary retention, inability to urinate, or urinary incontinence, loss of bladder control. Complications can include urinary tract infections, bladder stones, and chronic kidney problems. The cause is unclear. Risk factors include a family history, obesity, type 2 diabetes, not enough exercise, and erectile dysfunction. Medications like pseudoephedrine, anticholinergics, and calcium channel blockers may worsen symptoms. The underlying mechanism involves the prostate pressing on the urethra thereby making it difficult to pass urine out of the bladder. Diagnosis is typically based on symptoms and Physical examination, examination after ruling out other possible causes. Treatment options include lifestyle changes, medications, a number of procedures, and surgery. In th ...
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Volumetric Flow Rate
In physics and engineering, in particular fluid dynamics, the volumetric flow rate (also known as volume flow rate, or volume velocity) is the volume of fluid which passes per unit time; usually it is represented by the symbol (sometimes \dot V). Its SI unit is cubic metres per second (m3/s). It contrasts with '' mass flow rate'', which is the other main type of fluid flow rate. In most contexts a mention of "rate of fluid flow" is likely to refer to the volumetric rate. In hydrometry, the volumetric flow rate is known as '' discharge''. The volumetric flow rate across a unit area is called '' volumetric flux'', as defined by Darcy's law and represented by the symbol . Conversely, the integration of a volumetric flux over a given area gives the volumetric flow rate. Units The SI unit is cubic metres per second (m3/s). Another unit used is standard cubic centimetres per minute (SCCM). In US customary units and imperial units, volumetric flow rate is often expressed as ...
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Dot (diacritic)
When used as a diacritic mark, the term dot refers to the glyphs "combining dot above" (, and "combining dot below" ( which may be combined with some letters of the extended Latin alphabets in use in a variety of languages. Similar marks are used with other scripts. Overdot Language scripts or transcription schemes that use the dot above a letter as a diacritical mark: * In some forms of Arabic romanization, stands for '' ghayn'' (غ). * The Latin orthography for Chechen includes ''ċ'', ''ç̇'', ''ġ'', ''q̇'' and ''ẋ'', corresponding to Cyrillic ''цӏ'', ''чӏ'', ''гӏ'', ''къ'' and ''хь'' and representing , , , and respectively. * Traditional Irish typography, where the dot denotes lenition, and is called a or "dot of lenition": ''ḃ ċ ḋ ḟ ġ ṁ ṗ ṡ ṫ''. Alternatively, lenition may be represented by a following letter ''h'', thus: ''bh ch dh fh gh mh ph sh th''. In Old Irish orthography, the dot was used only for ''ḟ ṡ'', while the fol ...
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Flow Measurement
Flow measurement is the quantification of bulk fluid movement. Flow can be measured using devices called flowmeters in various ways. The common types of flowmeters with industrial applications are listed below: * Obstruction type (differential pressure or variable area) * Inferential (turbine type) * Electromagnetic * Positive displacement meter, Positive-displacement flowmeters, which accumulate a fixed volume of fluid and then count the number of times the volume is filled to measure flow. * Fluid dynamic (vortex shedding) * Anemometer * Ultrasonic flow meter * Mass flow meter (Coriolis force). Flow measurement methods other than positive-displacement flowmeters rely on forces produced by the flowing stream as it overcomes a known constriction, to indirectly calculate flow. Flow may be measured by measuring the velocity of fluid over a known area. For very large flows, tracer methods may be used to deduce the flow rate from the change in concentration of a dye or radioisotope. ...
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